MLB Game Preview: Cincinnati Reds (20-14) vs. Chicago Cubs (22-12)

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Venue: Wrigley Field — Chicago, Illinois

First Pitch: 7:40 PM ET / 6:40 PM CT / 4:40 PM PT

Surface: Natural grass

Broadcast: Marquee Sports Network, Bally Sports Ohio, MLB.TV

WEATHER REPORT — WRIGLEY FIELD

Temperature: 58–62°F at first pitch

Wind: Blowing out to left‑center at 14–18 mph — major boost for right‑handed power

Humidity: 55%

Precipitation: <10% chance

Ballpark Impact:

Classic Wrigley “wind‑out” game

Expect elevated run scoring

Fly‑ball pitchers at a disadvantage

INJURY REPORT

Cincinnati Reds

Elly De La Cruz (SS)Probable, minor quad tightness

Christian Encarnacion‑Strand (1B)Out, wrist injury

Hunter Greene (SP)Out, shoulder fatigue

Alexis Díaz (CL)Probable, light workload management

Chicago Cubs

Seiya Suzuki (RF)Probable, oblique tightness

Dansby Swanson (SS)Questionable, ankle soreness

Justin Steele (SP)Out, forearm strain

Adbert Alzolay (RP)Out, elbow inflammation

TEAM RECORDS & PERFORMANCE

Cincinnati Reds (20–14)

Run Differential: +18

Road Record: 10–7

Last 10 Games: 6–4

Offense: 4.92 runs/game

Pitching: 4.21 ERA

Bullpen: 3.88 ERA (top‑12 MLB)

Chicago Cubs (22–12)

Run Differential: +35

Home Record: 12–6

Last 10 Games: 7–3

Offense: 5.01 runs/game

Pitching: 3.89 ERA

Bullpen: 3.71 ERA (top‑10 MLB)

RECENT TEAM FORM

Cincinnati Reds

Offense hot: 5.3 runs/game over last 8

De La Cruz and Steer driving production

Rotation inconsistent without Greene

Bullpen strong in late innings

Chicago Cubs

Offense surging: 5.6 runs/game over last 7

Suzuki and Bellinger heating up

Pitching staff stabilizing despite injuries

Excellent situational hitting

PROBABLE STARTING PITCHERS

Cincinnati — Graham Ashcraft (RHP)

2026 Season: 3–2, 4.11 ERA, 1.29 WHIP

Strengths: Heavy sinker, induces ground balls

Weaknesses: Vulnerable when elevated — dangerous in wind‑out games

Vs. Cubs: 4.02 career ERA

Chicago — Jordan Wicks (LHP)

2026 Season: 4–1, 3.66 ERA, 1.24 WHIP

Strengths: Changeup effectiveness, good command

Weaknesses: Hard contact vs. right‑handed hitters

Vs. Reds: First career start vs. Cincinnati

KEY PLAYER MATCHUPS

1. Elly De La Cruz (CIN) vs. Jordan Wicks (CHC)

De La Cruz crushes left‑handed pitching

Wicks must keep the ball down to avoid extra‑base damage Edge: Reds

2. Cody Bellinger (CHC) vs. Graham Ashcraft (CIN)

Bellinger thrives vs. sinkerballers

Wind out boosts his HR probability Edge: Cubs

3. Spencer Steer (CIN) vs. Cubs Bullpen

Steer’s contact profile plays well in Wrigley

Cubs’ bullpen strong but vulnerable to right‑handed power Edge: Even

4. Ian Happ (CHC) vs. Wrigley Conditions

Happ’s switch‑hitting power plays well with wind out Edge: Cubs

SERIES HISTORY

2025–26 Season Series: Reds lead 7–6

Last 10 Meetings: Even (5–5)

At Wrigley Field: Cubs have won 4 of last 6

Games often high‑scoring due to park factors and division familiarity.

BETTING TRENDS

Cincinnati Reds

6–3 in last 9 road games

Over is 5–2 in last 7

4–1 in last 5 vs. NL Central

Chicago Cubs

7–2 in last 9 home games

Over is 6–3 in last 9

8–3 in last 11 vs. teams above .500

Game Odds

Cincinnati Reds                 11.5

Chicago Cubs                     – 207

Odds Courtesy of Sports Odds Direct as of Sunday, May 3, 2026