The Cleveland Guardians and Pittsburgh Pirates are set to clash in an intriguing MLB regular-season matchup on April 20, 2025, at PNC Park in Pittsburgh, Pennsylvania. With both teams looking to gain momentum early in the season, this game promises to be a competitive battle.

Game Details
- Date: April 20, 2025
- Time: 1:35 PM ET
- Venue: PNC Park, Pittsburgh
- Season Phase: Regular Season
Team Performance & Key Players
Cleveland Guardians
The Guardians have been solid offensively, with Steven Kwan and Kyle Manzardo leading the charge. Kwan has been consistent at the plate, delivering key hits, while Manzardo has shown power-hitting ability, including a recent home run against Pittsburgh. José Ramírez remains a crucial piece in Cleveland’s lineup, providing both offensive production and veteran leadership.
Pittsburgh Pirates
The Pirates have had a mixed start to the season, with Oneil Cruz and Jack Suwinski being key contributors. Cruz’s speed and power make him a dangerous offensive weapon, while Suwinski has been reliable in clutch situations. Paul Skenes, Pittsburgh’s young ace, has been a standout performer, though he struggled in his last outing against Cleveland.
Pitching Matchup
Cleveland is expected to start Logan Allen (1-1, 2.30 ERA), who has been effective in limiting runs. Pittsburgh will counter with Mitch Keller (1-2, 4.30 ERA), who is looking to bounce back after a few inconsistent starts. Keller’s ability to control the strike zone will be key in containing Cleveland’s hitters.
Game Odds
Cleveland Guardians 8
Pittsburgh Pirates – 112
Odds Courtesy of Sports Odds Direct as of Saturday, April 19, 2025