Venue & Game Details
Location: Notre Dame Stadium, South Bend, IN
Kickoff: 7:30 p.m. ET (NBC / Peacock)
Conference: Independent (Notre Dame) vs. Big Ten (USC)
Weather Forecast: ~58°F at kickoff, partly cloudy, light winds 5–8 mph,
Team Recent Form
Notre Dame:
Wins: NC State (36–7), Kentucky, Wake Forest, UConn
Losses: Miami (FL), Alabama
Trend: Irish averaging 40.0 PPG (14th nationally), defense allowing 20.8 PPG (47th).
USC:
Wins: Michigan (31–13), Arizona, Stanford, others
Loss: Penn State
Trend: Trojans averaging 45.5 PPG (3rd nationally), defense allowing 21.3 PPG (51st).
Injury Report
Notre Dame:
WR Jordan Faison – Probable (ankle)
RB Jeremiyah Love – Healthy, leads team in rushing
USC:
QB Jayden Maiava – Healthy, 71.9% completion rate
RB Waymond Jordan – Probable (shoulder)
Key Player Matchups
QB CJ Carr (ND): 1,622 yards, 13 TDs, 3 INTs, 66.5% completion.
RB Jeremiyah Love (ND): 530 yards, 8 TDs – versatile runner and receiver.
WR Jordan Faison (ND): 376 yards, 2 TDs – reliable target.
QB Jayden Maiava (USC): 1,852 yards, 13 TDs, 2 INTs, 71.9% completion.
RB Waymond Jordan (USC): 576 yards, 5 TDs – explosive runner.
WR Makai Lemon (USC): 682 yards, 6 TDs – game-breaking receiver.
Series History
Notre Dame leads the all-time series 50–38–5.
Last meeting (2024): Notre Dame won 48–20 in Los Angeles.
USC has not won in South Bend since 2011.
Betting Trends:
Both teams are 3-3 ATS this season.
Notre Dame is 2-1 ATS as a favorite of 9+ points.
USC has not been an underdog yet in 2025.
The Over has hit in 2 of USC’s last 3 games.
Historical Betting Results
Notre Dame has covered in 2 of last 3 vs. USC.
The Over has cashed in 3 of last 5 meetings.
Average margin of victory in last two ND wins: +19.5 points.
Game Odds
USC Trojans 60.5
Notre Dame Fighting Irish – 10.5
Odds Courtesy of Sports Odd Direct as of Friday, October 17, 2025
