First Pitch: 7:10 PM CT
Venue: Guaranteed Rate Field — Chicago, Illinois
Probable Pitchers: RHP Joe Ryan (MIN) vs. RHP Seth Burke (CWS)
Venue Profile — Guaranteed Rate Field
- Location: South Side, Chicago
- Dimensions: LF 330 ft, CF 400 ft, RF 335 ft
- Park Factor: One of the most HR-friendly parks in the American League.
- Surface: Kentucky bluegrass
- Notes: Warm weather + light winds often create a launchpad effect for right-handed power.
Weather Forecast
- Temperature: 74–77°F at first pitch
- Wind: 8–12 mph blowing out to left-center
- Humidity: 58%
- Precipitation: <5%
- Impact:
- Boost for right-handed power hitters (Buxton, Lewis, Vaughn, Eloy).
- Slightly elevated run-scoring environment.
Injury Report
Minnesota Twins
- Carlos Correa — Day-to-day (heel)
- Max Kepler — 10‑day IL (oblique)
- Jhoan Duran — 15‑day IL (shoulder)
- Brock Stewart — 60‑day IL (lat)
Chicago White Sox
- Luis Robert Jr. — OUT (hamstring)
- Yoán Moncada — 10‑day IL (back)
- Garrett Crochet — 15‑day IL (forearm)
- Michael Kopech — 60‑day IL (elbow)
Team Records & Recent Form
Minnesota Twins (26–28)
- Last 10: 5–5
- Road Record: 11–15
- Run Differential: –9
- Trend: Offense inconsistent; pitching stabilizing behind Ryan and Ober.
Chicago White Sox (27–26)
- Last 10: 6–4
- Home Record: 15–11
- Run Differential: +4
- Trend: Lineup producing despite injuries; bullpen shaky late.
Pitching Matchup Breakdown
MIN — RHP Joe Ryan
- 2026 Stats: 3.77 ERA | 1.18 WHIP | 9.1 K/9
- Profile:
- Four-seam fastball with elite carry (92–94 mph).
- Splitter/changeup combo keeps LHB off balance.
- Fly-ball pitcher — vulnerable in HR-friendly parks.
- Matchup Notes:
- Guaranteed Rate Field is dangerous for his profile.
- White Sox right-handed bats (Vaughn, Eloy) match up well.
CWS — RHP Seth Burke
- 2026 Stats: 4.02 ERA | 1.29 WHIP | 7.8 K/9
- Profile:
- Sinker/slider righty with good command.
- Generates ground balls but can be hit hard when slider flattens.
- Struggles vs. lineups with multiple RH power bats.
- Matchup Notes:
- Twins’ right-handed core (Lewis, Buxton, Miranda) is a tough matchup.
- Burke’s sinker moves into Lewis’ launch angle sweet spot.
Key Player Matchups
Twins Hitters vs. Burke
- Royce Lewis: Elite vs. sinkers; HR threat with wind blowing out.
- Byron Buxton: Crushes sliders from RHP; speed adds pressure.
- Jose Miranda: Hot bat; excellent vs. low-velo breaking balls.
White Sox Hitters vs. Ryan
- Andrew Vaughn: Perfect matchup vs. Ryan’s rising fastball.
- Eloy Jiménez: Loves high fastballs; HR candidate.
- Colson Montgomery: Patient LHB who can force deep counts.
Series History
- 2025 Season: Twins won 11–8.
- 2026 Season (so far): White Sox lead 2–1.
- At Guaranteed Rate Field (last 3 years): Twins 13–12.
- Trend: Tight, competitive series with frequent overs.
Betting Trends
Minnesota Twins
- 4–1 in last 5 Ryan road starts
- Over is 6–2 in last 8 games
- Twins 7–3 in last 10 vs. AL Central
Chicago White Sox
- 5–2 in last 7 home games
- Over is 8–3 in last 11 games
- White Sox 6–1 in last 7 vs. losing teams
Head-to-Head
- Over is 7–2 in last 9 meetings
- Road team is 5–1 in last 6 matchups
Game Odds
Minnesota Twins – 115
Chicago White Sox 7.5
Odds Courtesy of Sports Odds Direct as of Monday, May 25, 2026
