Venue & Game Details
Stadium: Lucas Oil Stadium, Indianapolis, Indiana
Kickoff: 4:25 p.m. ET (3:25 p.m. local)
Broadcast: CBS: Andrew Catalon, Charles Davis, Jason McCourty, AJ Ross (field reporter)
Conference Matchup: AFC South divisional game
Weather Forecast
Conditions: Indoor stadium – no weather impact
Outside Indianapolis: 61°F, partly cloudy
Injury Report
Titans:
WR Calvin Ridley (hamstring) – Questionable
CB L’Jarius Sneed (quad) – Doubtful
DT Jeffery Simmons (hamstring) – Questionable
WR Bryce Oliver (knee) – Questionable
LB Arden Key (quad) – Questionable
Colts:
WR Josh Downs (concussion) – Questionable
DE Tyquan Lewis (groin) – Questionable
DE Samson Ebukam (knee) – Questionable
CB Kenny Moore II (Achilles) – Questionable
CB Charvarius Ward (concussion) – Out (IR)
Key Player Matchups
Cam Ward (TEN QB): Rookie with 1,356 yards, 4 TD, 5 INT; sacked 30 times in 7 games. Faces Indy’s opportunistic defense.
Jonathan Taylor (IND RB): Leads NFL with 697 rushing yards and 10 TDs; scored 3 TDs vs. Titans in Week 3.
Daniel Jones (IND QB): 1,790 yards, 10 TD, 3 INT; thriving in Shane Steichen’s system.
Titans O-line vs. Colts Pass Rush: Tennessee has allowed the 2nd-most sacks in NFL; Indy’s front could dominate.
Recent Team Forms
Titans: Lost 31-13 to Patriots; offense averaging 13.7 PPG (last in NFL). Defense giving up 27.4 PPG.
Colts: Beat Chargers 38-24; offense averaging 33.1 PPG (1st in NFL). Defense allowing 20.0 PPG (9th).
Series History
All-time: Colts lead 40-22
Last Meeting (Week 3, 2025): Colts 41, Titans 20 in Nashville
Trend: Colts have won 5 straight; Titans last won in 2022
Betting Trends:
Titans: 2-5 ATS, 4-3 O/U
Colts: 5-2 ATS, 4-3 O/U
Colts are 3-1 ATS at home; Titans 2-2 ATS on road
Historical Betting Results
2025 (Week 3): Colts -6, won 41-20 (Over 42.5)
2024 (Dec): Colts -4, won 38-30 (Over 42.5)
2024 (Oct): Colts +2.5, won 20-17 (Under 41.5)
2023 (Dec): Colts -1, won 31-28 OT (Over 42)
2022 (Oct): Titans +2.5, won 19-10 (Under 43)
Projected Score: Colts 34, Titans 13
TITANS NOTES:
• QB CAM WARD (rookie) completed 25 of 34 atts. (73.5 pct.) for 255 yards & TD in Week 7. Aims for his 3rd in row with 220+ pass yards & TD. Completed 23 of 38 atts. (60.5 pct.) for 219 yards & TD in last meeting. • RB TONY POLLARD had 61 scrimmage yards (43 rec., 18 rush) last week. Has 45+ scrimmage yards in each of his 7 games this season. Had 59 scrimmage yards (45 rush, 14 rec.) & rush TD in Week 3 meeting. • RB TYJAE SPEARS had 66 scrimmage yards (39 rec., 27 rush) & 2 rush TDs in his last game vs. Ind. (12/22/24). • WR CHIMERE DIKE (rookie) had 4 catches for 70 yards & 1st-career TD last week. Had career-high 162 kick-return yards in last meeting. • WR ELIC AYOMANOR (rookie) had TD catch in Week 3 meeting. • TE CHIG OKONKWO aims for his 3rd in row vs. Ind. with 5+ catches & 65+ rec. yards. • DT JEFFERY SIMMONS has 3.5 sacks & 7 TFL in his past 4. Had 9 tackles & sack in last road meeting (12/22/24). • DT T’VONDRE SWEAT had 6 tackles & 1st sack of season in Week 7. • LB CODY BARTON has 6+ tackles in 3 of his 4 road games this season. Aims for his 3rd in row vs. Ind. with 6+ tackles. • LB CEDRIC GRAY led team with 10 tackles in Week 7. Aims for his 5th in row with 10+ tackles. Has TFL in 3 of his past 4. • LB DRE’MONT JONES aims for his 3rd in row with sack. • LB JIHAD WARD had 1st sack of season last week. Has PD in 2 of his past 3. • S XAVIER WOODS had 2nd-career sack in Week 7. Has 4+ tackles in 5 of his past 6. Had 6 tackles & PD in last meeting. • S AMANI HOOKER had 6 tackles last week. Had 5 tackles & 2 PD in Week 3 meeting. • S QUANDRE DIGGS had 7 tackles in Week 7. Has 6+ tackles in 3 of his past 4 vs. Ind.
COLTS NOTES:
• COLTS lead NFL in scoring offense (33.1 ppg) & rush TDs (16). • QB DANIEL JONES passed for 288 yards & 2 TDs vs. 0 INTs with 113.4 rating in Week 7. Is 3rd QB since 1950 with 100+ rating in 6 of 1st 7 starts with team. Aims for his 4th in row with 210+ pass yards, 100+ rating & 2+ TD passes. Passed for 228 yards & TD with 113.4 rating in last meeting. • RB JONATHAN TAYLOR led team with 132 scrimmage yards (94 rush, 38 rec.) & 3 rush TDs. Leads NFL with 10 rush TDs in 2025. Is 3rd player in past 20 seasons with 3 games with 3+ rush TDs in a season. Aims for his 3rd in row vs. Ten. with 110+ scrimmage yards & 3 rush TDs. • WR MICHAEL PITTMAN had 7 catches for 58 yards & TD in Week 7. Has TD catch in 4 of his past 5. Had 6 catches for 73 yards & TD in last meeting. • WR ALEC PIERCE led team with 98 rec. yards & had 5 catches last week. • TE TYLER WARREN had 4 catches for 69 yards & TD in Week 7. Is 3rd rookie tight end in SB era with TD in 4 consecutive games. Aims for his 5th in row with 4+ catches. • DT DEFOREST BUCKNER had 5 tackles & 2 sacks last week. Has sack in 2 of his past 3. Aims for his 5th in row vs. Ten. with 5+ tackles. Has PD in 2 of his past 3 vs. Ten. • DE LAIATU LATU had 3 tackles & sack in Week 7. Has TFL in 3 of his past 4. • LB ZAIRE FRANKLIN had 5 tackles & PD last week. Has 5+ tackles in 6 games this season. Aims for his 3rd in row vs. division with 6+ tackles & PD. • CB KENNY MOORE had season-high 8 tackles & PD in Week 7. Has PD in 3 of his past 4. Had INT-TD in last meeting. • S CAM BYNUM had season-high 8 tackles last week. Has PD in 3 of his 4 at home this season. • S NICK CROSS had 6 tackles & INT in Week 7. Has PD in 2 of his past 3. Had 7 tackles & TFL in last meeting.
Game Odds
Tennessee Titans 47.5
Indianapolis Colts – 14.5
Odds Courtesy of Sports Odd Direct as of Saturday, October 25, 2025
