NFL Game Preview: San Francisco 49ers (6-0-0) vs. Atlanta Falcons (2-4-0)

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Atlanta Falcons logo

FOX: Kenny Albert, Greg Olsen, Pam Oliver (field reporter)

Kickoff is scheduled for 1:00 PM ET

Mercedes-Benz Stadium | Referee: Clay Martin

Regular Season: SF leads series, 48-32-1 (home team won past 3) Last reg. season meeting: 10/19/25: ATL 10 at SF 20

Kyle Shanahan (SF) vs. Opp. (incl. postseason): 2-2 Reg. Season: 88-67 (.568) Kevin Stefanski (ATL) vs. Opp. (incl. postseason): 1-1 Reg. Season: 47-60 (.439

San Francisco Last Game: W, 23-17 vs. WAS (Week 6

Atlanta Last Game: L, 31-23 vs. CHI (Week 6)

49ERS NOTES

• 49ERS are 6-0 for 4th time in franchise history (1984, 1990 & 2019). • QB BROCK PURDY completed 21 of 29 pass atts. (72.4 pct.) for 264 yards & TD for 111.9 rating & had 28 rush yards in Week 6. Ranks tied-1st with 14 TD passes in 2026. Has 2+ TD passes in 5 of his past 6. Aims for 3rd in row on road with 2+ TD passes & 90+ rating. • RB CHRISTIAN MCCAFFREY had 117 scrimmage yards (64 rush, 53 rec.) & 2 rush TDs in Week 6. Ranks 2nd with 13,519 scrimmage yards (7,939 rush, 5,580 rec.) since 2017 & tied-2nd with 105 scrimmage TDs (69 rush, 36 rec.). Had 201 scrimmage yards (129 rush, 72 rec.) & 2 rush TDs in last meeting. Aims for 6th in row vs. Atl. with 130+ scrimmage yards. • WR MIKE EVANS had 3 receptions for team-high 94 yards in Week 6. Has 111 career TD receptions, tied with HOFer Tony Gonzalez for 9th-most in NFL history. Aims for 4th in row with 75+ rec. yards. Had 6 catches for 132 yards in last meeting. Has 5+ receptions in 4 of his past 5 vs. Atl. • TE GEORGE KITTLE had 5 catches for 69 yards & TD in Week 6. Has TD catch in 4 of his past 5. Ranks tied-3rd with 5 TD catches this season. Has 80+ rec. yards in 3 of his past 4 vs. Atl. • LB FRED WARNER had 8 tackles in Week 6. Ranks 3rd with 58 tackles in 2026. Aims for 4th in row vs. Atl. with 9+ tackles. Has PD in 2 of his past 3 vs. Atl. • LB JADEN DUGGER (rookie) led team with career-high 11 tackles in Week 6. Aims for 3rd in row with 9+ tackles. • DL MYKEL WILLIAMS had 1st sack of season in Week 6. • DL GRACEN HALTON (rookie) had sack in Week 6. Aims for 3rd in row with sack. Ranks 2nd among rookies with 5 TFL this season. • DL OSA ODIGHIZUWA had sack in Week 6. Aims for 3rd in row with sack. • CB DEOMMODORE LENOIR had PD in last meeting. • S MALIK MUSTAPHA had PD in Week 6. Aims for 4th in row with PD

FALCONS NOTES

• QB MICHAEL PENIX passed for 225 yards & 3 TDs for 108.8 rating in Week 6. Aims for 5th in row with 220+ pass yards & TD pass. Has 100+ rating in 4 of his past 5. Aims for 3rd in row at home with TD pass. Had 241 pass yards & TD pass in last meeting. • RB BIJAN ROBINSON has 115+ scrimmage yards in 3 of his past 4. Ranks 1st with 785 scrimmage yards (641 rush, 144 rec.) this season. Had 92 scrimmage yards (52 rec., 40 rush) & TD catch in last meeting. • WR DRAKE LONDON has 95+ rec. yards in 3 of his past 4. • WR JAHAN DOTSON led team with 87 rec. yards & had TD catch in Week 6. Has TD reception in 2 of his past 3. • TE KYLE PITTS had 2 TD receptions in Week 6 & aims for 3rd in row with TD catch. Has 60+ rec. yards in 2 of his past 3 vs. SF. • DL BRANDON DORLUS had sack, 2 TFL & PD in Week 6. Had TFL in last meeting. • DL LACALE LONDON had 5 tackles & sack in Week 6 & aims for 3rd in row with 5+ tackles. • DL GERVON DEXTER aims for 3rd in row with TFL. • CB MIKE HUGHES had 7 tackles & TFL in Week 6. Aims for 3rd in row with 6+ tackles. Has TFL in 2 of his past 3. Had 5 tackles & PD in last meeting. Aims for 3rd in row vs. SF with PD. • CB C.J. HENDERSON has 8+ tackles in 2 of his past 3. Has PD in 5 of his past • 6. Only player with 6+ PD, FF & FR this season. • CB AVIEON TERRELL (rookie) had season-high 5 tackles in Week 6. • S JESSIE BATES had 7 tackles & FF in Week 6. Aims for 3rd in row with 6+ tackles. 1 of 3 (Elijah Ponder & Gracen Halton) with FF & FR-TD this season. Had 10 tackles in last meeting & aims for 4th in row vs. SF with 9+ tackles. • S XAVIER WATTS had TFL in Week 6. Has 5+ tackles in 4 of his past 5. Had 9 tackles in last meeting.

Game Odds

San Francisco 49ers        – 2.5

Atlanta Falcons                 50

Odds Courtesy of Sports Odd Direct as of Saturday, October 24, 2026

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