NFL Game Preview: Arizona Cardinals (1-4-0) vs. Los Angeles Rams (2-3-0)

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Los Angeles Rams logo

FOX: Kenny Albert, Greg Olsen, Pam Oliver (field reporter)

Kickoff is scheduled for 4:05 PM ET

SoFi Stadium | Referee: Clay Martin

Regular Season: LAR leads series, 51-41-2 (LAR won past 3)

Last reg. season meeting: 1/4/26: ARI 20 at LAR 37

Mike LaFleur (ARI) vs. Opp. (incl. postseason): 0-0 Reg. Season: 1-4 (.200)

Sean McVay (LAR) vs. Opp. (incl. postseason): 16-3 Reg. Season: 94-60 (.610)

Arizona Last Game: L, 45-21 vs. DET (Week 5)

LA Rams Last Game: L, 37-34 vs. BUF (OT) (Week 5)

CARDINALS NOTES

• QB JACOBY BRISSETT passed for 292 yards & 3 TDs for 91.8 rating in Week 5. Aims for 18th in row with TD pass. Has 280+ pass yards in 2 of his past 3. Passed for 243 yards & 2 TDs in last meeting. Aims for 4th in row vs. LAR with 2+ TD passes. • RB JEREMIYAH LOVE leads all rookies with 245 rush yards this season & ranks tied-2nd with 2 scrimmage TDs. Is only rookie RB with 100+ scrimmage yards in a single game this season. • WR KENDRICK BOURNE had 5 receptions for team-high 70 yards in Week 5. • WR MICHAEL WILSON has 7+ receptions & 85+ rec. yards in 2 of his past 3. Aims for 7th in row on road with 5+ receptions & 50+ rec. yards. Had 5 receptions for 99 yards & TD in last meeting. Aims for his 3rd in row vs. LAR with 95+ rec. yards & TD catch. • TE TREY MCBRIDE had 9 catches for 66 yards & TD in Week 5. Has 389 career receptions since 2022, most catches by a TE in 1st 5 seasons in NFL history. Leads all TEs with 42 receptions & ranks 3rd with 308 rec. yards this season. Has 75+ rec. yards in 2 of his past 3 on road. Aims for 6th in row vs. LAR with 5+ receptions. • TE TEAGAN QUITORIANO had career-high 2 rec. TDs last week. • LB BARON BROWNING had 2 FFs & sack in Week 5. Has TFL in 2 of his past 3. • LB JOSH SWEAT has sack in 2 of his past 3 vs. LAR. • LB MACK WILSON had 7 tackles last week & has 7+ tackles in 3 of his past 4. • DL ROY LOPEZ had sack in Week 5. Aims for his 3rd in row with TFL. • CB DENZEL BURKE had 6 tackles in Week 5. Aims for his 3rd in row on road with PD. Aims for his 3rd in row vs. LAR with 5+ tackles. • S BUDDA BAKER led team with 11 tackles & had sack in Week 5. Had 9 tackles & 2 TFL in last meeting. Has 7+ tackles in 4 of his past 5 vs. LAR. Ranks 1st among DBs with 1,039 tackles since 2017.

RAMS NOTES

• QB MATTHEW STAFFORD completed 40 of 54 atts. (74.1 pct.) for 383 yards & 3 TDs for 111.9 rating in Week 5. Has 457 career TD passes, incl. playoffs, 6th-most in NFL history. Is 1st player in NFL history with 150+ TD passes with 2 teams (282 with Det; 150 with LAR). Aims for his 5th in row with 315+ pass yards. Aims for 3rd in row vs. Ari. with 3+ TD passes. • RB KYREN WILLIAMS had 76 scrimmage yards (49 rush, 27 rec.) & rush TD in Week 5. Aims for his 5th in row with 75+ scrimmage yards & 3rd in row with rush TD. Has 70+ scrimmage yards in 5 of his past 6 vs. Ari. & TD in 5 of his past 6 vs. Ari. Aims for 3rd in row at SoFi Stadium with TD. • RB BLAKE CORUM had rush TD in Week 5. Aims for 3rd in row at SoFi Stadium with 70+ scrimmage yards. Rushed for 128 yards & 2 TDs in 2025 Week 14 meeting. • WR DAVANTE ADAMS had 2 TD receptions last week. Has 121 career rec. TDs, tied with HOFer Larry Fitzgerald for 6th-most in NFL history. Ranks tied-4th with 4 TD catches this season. Aims for his 3rd in row at SoFi Stadium with 2+ rec. TD. Ranks 3rd with 13,074 rec. yards since 2014. • WR PUKA NACUA led team with career-high 17 receptions for 138 yards & had TD catch in Week 5, 2nd-most catches in a single game in team history. Ranks 3rd with 4,528 rec. yards since 2023. Aims for his 3rd in row with 125+ rec. yards. Aims for his 4th in row vs. Ari. with 75+ rec. yards. • TE TYLER HIGBEE had 5 receptions for 83 yards in Week 5. • LB NATE LANDMAN led team with 13 tackles & 2 FFs in Week 5, only player to do so in a single game this season. • LB BYRON YOUNG aims for 4th in row vs. Ari. with sack. • DE AARON DONALD had FR in Week 5. • CB TRENT MCDUFFIE & S QUENTIN LAKE rank tied-2nd with 7 PD each in 2026. • S KAM CURL had 8 tackles & TFL in Week 5. Has PD in 2 of his past 3 vs. Ari. • S KAMREN KINCHENS aims for 5th in row with 6+ tackles.

Game Odds

Arizona Cardinals            51.5

Los Angeles Rams            -12.5

Odds Courtesy of Sports Odd Direct as of Saturday, October 17, 2026

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