MLB NL Division Series Game 2 Preview: San Diego Padres (0-1) vs. Milwaukee Brewers (1-0)

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American Family Field, Milwaukee, Wisconsin
First pitch: 4:00 p.m. ET
TV: FS1

This is Game 2 of the National League Division Series. Milwaukee took Game 1 by a 3-2 score on Saturday (home runs from Jackson Chourio and William Contreras). The Brewers own the best regular-season record in baseball (103-59) and a strong home mark (55-26). The Padres (91-71) reached the NLDS by sweeping the Cubs in the Wild Card Series and enter needing a road win to even the best-of-five.

Starting Pitchers

Padres: RHP Michael King (12-10, 3.21 ERA, 1.18 WHIP, 159 K in regular season). Strong postseason form so far (1-0, 0.00 ERA in limited work). Command-oriented right-hander who can miss bats and induce weak contact.

Brewers: RHP Logan Henderson (11-3, 2.47 ERA, 0.84 WHIP, high K/9). Excellent regular-season numbers with strong strikeout and walk rates; making his postseason debut.

Current/Projected Lineups

Padres (typical recent/projected order):
Fernando Tatis Jr. (RF)
Dustin Harris (LF)
Manny Machado (3B)
Ty France (1B)
Jackson Merrill (CF)
Xander Bogaerts (SS)
Ethan Salas or Luis Campusano (C)
Austin Hays / Miguel Andujar / Gavin Sheets (DH options)
Jake Cronenworth (2B)

Brewers (typical recent/projected order):
Jackson Chourio (LF/CF)
Brice Turang (2B)
William Contreras (C)
Jake Bauers (1B)
Christian Yelich (DH)
Garrett Mitchell / Sal Frelick (OF)
Cooper Pratt / Joey Ortiz (IF)
David Hamilton or similar (utility)

Injury Reports

Padres:

Jeremiah Estrada (RP) – Shoulder (15-day IL).

Casey Mize (SP) – Ankle (15-day IL).

Lucas Giolito (SP) – Elbow (60-day IL).

Ramón Laureano (OF) – Hip (60-day IL).

Luis Rengifo (INF/OF) – Knee (60-day IL).

Walker Buehler (SP) – Paternity list (expected back around Oct. 6).

Other long-term absences include Bryan Hoeing and Rodolfo Durán.

Brewers:

Brandon Woodruff (SP) – Shoulder (60-day IL; working toward possible late-postseason return).

Grant Anderson (RP) – Biceps (15-day IL).

Quinn Priester (SP), Angel Zerpa (RP), Brian Fitzpatrick (RP) – 60-day IL (various).

Andrew Vaughn recently activated from IL (illness).

Both bullpens have depth but are navigating some key absences.

Weather Forecast

Sunny and pleasant. High near 65–68°F with northwest winds 5–15 mph. Clear skies overnight (lows mid-40s). No precipitation expected. American Family Field has a retractable roof, but conditions favor an open-air game with mild temperatures ideal for baseball.

Recent Team Forms

Padres: Strong late-season run and a Wild Card sweep of the Cubs. They have been productive offensively in stretches (power from Tatis, Machado, Merrill) and showed resilience after the Game 1 loss. Postseason ERA has been excellent early.

Brewers: Elite regular season, finished with a strong stretch (including 15 of final 18 wins in some reports), and took Game 1 at home. Best team batting average in MLB during the regular season; strong home performance and pitching depth. Last 10 games overall have been dominant.

Series History

Padres led the regular-season series 4-3 heading into the playoffs. Recent meetings were competitive; Milwaukee took the most recent (Game 1 of this series). Brewers have been excellent at home overall. This is the second of a potential five-game series (Games 3–4 in San Diego if necessary).

Key Player vs. Player Matchups

Michael King vs. Brewers lineup (Chourio, Turang, Contreras, Yelich, Bauers): King must limit hard contact from Milwaukee’s contact-and-power mix. Chourio has been hot recently.

Logan Henderson vs. Padres lineup (Tatis, Machado, Merrill, Bogaerts, France): Henderson’s command and strikeout ability will be tested by San Diego’s veteran hitters who can punish mistakes. Tatis remains a high-impact threat.

Bullpen battles: Both sides have high-leverage arms; late-inning matchups (especially with potential closer availability) will be critical in a tight series.

Defense & baserunning: Milwaukee’s infield (Turang, Pratt/Ortiz) grades highly; Padres rely on athleticism from Tatis, Merrill, and Cronenworth.

Game Odds

San Diego Padres             7

Milwaukee Brewers       – 132

Odds Courtesy of Sports Odds Direct as of Saturday, October 3, 2026

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