The Toronto Blue Jays (12-10) and Houston Astros (10-10) are set to open a three-game series on Monday, April 21, 2025, at Daikin Park in Houston. Both teams are looking to gain momentum as they approach the end of April, with the Astros coming off back-to-back wins for the first time this season.

Game Details
- Date: Monday, April 21, 2025
- Time: 8:10 PM ET
- Venue: Daikin Park, Houston
- TV Broadcast: SN1, SCHN
- Series Status: Game 1 of 3
Team Overview & Key Players
Houston Astros (10-10, 4th in AL West)
The Astros have struggled with consistency early in the season but are beginning to find their rhythm. Their pitching staff ranks ninth in MLB with a 3.63 ERA, while their offense has been slow to start, ranking 23rd in home runs (17) and 27th in slugging percentage (.334).
Key Players
- Isaac Paredes (INF) – Batting .250 with three home runs and seven RBIs over his last 10 games.
- Jose Altuve (2B) – Veteran leader; hitting .305 with three home runs.
- Hunter Brown (SP) – Set to start; holds a 2-1 record with a 1.50 ERA and 22 strikeouts in 24.2 innings.
Toronto Blue Jays (12-10, 4th in AL East)
The Blue Jays have been solid offensively, ranking fourth in MLB with a .259 team batting average. Their pitching staff has also been strong, averaging 9.6 strikeouts per nine innings (5th in MLB).
Key Players
- Vladimir Guerrero Jr. (1B) – Batting .305 with six doubles and 10 RBIs.
- Bo Bichette (SS) – Has four doubles and 14 hits over his last 10 games.
- Kevin Gausman (SP) – Set to start; holds a 2-1 record with a 2.49 ERA and 20 strikeouts in 25.1 innings.
Game 1 Pitching Matchup
Pitcher | Team | Record | ERA | Last Start |
---|---|---|---|---|
Hunter Brown | Astros | 2-1 | 1.50 | 6.0 IP, 0 ER vs. Cardinals |
Kevin Gausman | Blue Jays | 2-1 | 2.49 | 6.0 IP, 2 ER vs. Braves |
Brown has been dominant early in the season, while Gausman remains one of Toronto’s most reliable arms.
Game Outlook & Predictions
- Astros’ Strategy: Expect Houston to rely on pitching, with Brown aiming to control the game early.
- Blue Jays’ Adjustments: Toronto must capitalize on scoring opportunities and limit strikeouts against Brown.
- X-Factor: Vladimir Guerrero Jr.’s ability to drive in runs could be the difference-maker.
Game Odds
Toronto Blue Jays 7.5
Houston Astros – 135
Odds Courtesy of Sports Odds Direct as of Sunday, April 20, 2025