MLB Game Preview: St. Louis Cardinals (46-38) vs. Cleveland Guardians (40-41)

First pitch is set for 12:05 p.m. ET, with coverage on FOX Sports and MLB.tv.

Matchup	St. Louis Cardinals vs Cleveland Guardians
Date & Time	Sunday, June 29, 2025 – 12:05 p.m. ET
Venue	Progressive Field, Cleveland, OH
Broadcast	FOX Sports, MLB.tv

This is the series finale of a three-game interleague set. The Cardinals are looking to complete a sweep, while the Guardians aim to salvage a win at home.

Team Form & Trends

St. Louis Cardinals (46–38, 2nd in NL Central)

• Recent Form: 9 wins in last 12 games
• Offensive Surge: Averaging 5.1 runs per game during win streak
• Key Stat: 8th in MLB in scoring (4.71 runs/game)

Cleveland Guardians (41–41, 2nd in AL Central)

• Recent Form: Lost 4 of last 5 games
• Offensive Struggles: Ranked 25th in MLB in runs per game (3.74)
• Key Stat: Shut out in 2 of last 3 games

Starting Pitchers

Matthew Liberatore (LHP, STL)

• Record: 5–3 ERA: 3.89 WHIP: 1.28
• Last Start: 7 IP, 2 ER, 5 K vs Cubs (Win)
• Trend: Back-to-back quality starts; Cardinals have won his last 3 outings

Logan Allen (LHP, CLE)

• Record: 4–6 ERA: 4.30 WHIP: 1.36
• Last Start: 5.2 IP, 4 ER vs Blue Jays (Loss)
• Trend: Opponents hitting .291 vs him from the left side

Key Hitters to Watch

St. Louis Cardinals

• Brendan Donovan: .302 AVG, 6 HR, 31 RBI – team’s most consistent bat
• Alec Burleson: .300 AVG on the road, 2 HR, 5 RBI in last 5 games
• Lars Nootbaar: Team-high 11 HR, .267 AVG in last 5 games

Cleveland Guardians

• José Ramírez: .312 AVG, 13 HR, 38 RBI – team leader in all major categories
• Steven Kwan: .300 AVG, 18 doubles – elite contact hitter
• Carlos Santana: 9 HR, 36 BB – veteran presence with power

Head-to-Head & Betting Insights

• Cardinals have won 4 straight vs Guardians and 5 of last 7 overall
• St. Louis is 16–8 when favored by -124 or more this season
• Cleveland is 2–6 in its last 8 series and ranks 25th in team OPS