The Seattle Mariners (12-10) and Boston Red Sox (13-11) are set to open a three-game series on Tuesday, April 22, 2025, at Fenway Park in Boston. The Mariners enter the matchup riding a strong stretch, having won four consecutive series and going 9-3 over their last 12 games. Meanwhile, the Red Sox have been solid at home, boasting a 7-4 record at Fenway Park.

Game Details
- Date: Tuesday, April 22, 2025
- Time: 6:45 PM ET
- Venue: Fenway Park, Boston, MA
- TV Broadcast: NESN, ROOT Sports NW
- Series Status: First meeting of the season
Team Overview & Key Players
Boston Red Sox (13-11, 4th in AL East)
The Red Sox have been consistent offensively, ranking seventh in the AL with 24 home runs. Their pitching staff has been middle-of-the-pack, posting a 4.04 team ERA, which ranks 15th in MLB.
Key Players
- Wilyer Abreu (OF) – Batting .274 with five doubles, four home runs, and 15 RBIs.
- Trevor Story (INF) – Hitting .337 with five home runs, providing a strong offensive presence.
- Brayan Bello (SP) – Set to start; making his season debut after recovering from a shoulder strain.
Seattle Mariners (12-10, 3rd in AL West)
The Mariners have been one of the hottest teams in baseball, winning four straight series and outscoring opponents by 21 runs over their last 10 games. Their pitching staff has been solid, ranking 12th in MLB with a 3.78 ERA.
Key Players
- Cal Raleigh (C) – Leads the Mariners with nine home runs, providing power in the lineup.
- Jorge Polanco (INF) – Batting .324 over his last 10 games, adding consistency.
- Bryce Miller (SP) – Set to start; holds a 1-2 record with a 3.43 ERA, looking to build on his strong outing against Cincinnati.
Game 1 Pitching Matchup
Pitcher | Team | Record | ERA | Last Start |
---|---|---|---|---|
Brayan Bello | Red Sox | 0-0 | N/A | First start of the season |
Bryce Miller | Mariners | 1-2 | 3.43 | 5.0 IP, 0 ER vs. Reds |
Bello is making his season debut after a rehab stint in the minors, while Miller is looking to continue his strong form after a scoreless outing against Cincinnati.
Game Outlook & Predictions
- Red Sox’s Strategy: Expect Boston to rely on power hitting, with Abreu and Story leading the charge.
- Mariners’ Adjustments: Seattle must capitalize on Bello’s rustiness and maintain their strong pitching.
- X-Factor: Bryce Miller’s ability to control Boston’s lineup could be the difference-maker.
Game Odds
Seattle Mariners 9
Boston Red Sox – 130
Odds Courtesy of Sports Odds Direct as of Monday, April 21, 2025