MLB Game Preview: Seattle Mariners (11-15) vs. St. Louis Cardinals (14-10)

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St. Louis Cardinals logo

Venue: Busch Stadium — St. Louis, MO

First Pitch I scheduled for 5:15 PM ET

Broadcast: MLB.TV, Cardinals.TV, Mariners.TV

Weather Outlook — St. Louis, MO

Temperature: ~71°F at game time

Wind: ~7 mph WSW

Conditions: Mild, partly sunny

Impact: Slightly hitter‑friendly due to warm air and light wind

Injury Report

Seattle Mariners

Victor Robles — 10‑Day IL (Apr 24)

Patrick Wisdom — 10‑Day IL (Apr 25)

Brendan Donovan — 10‑Day IL (Apr 28)

Teddy McGraw — OUT (May 1)

Bryce Miller — 15‑Day IL (May 22)

St. Louis Cardinals

Matt Pushard — 15‑Day IL (Apr 24)

Hunter Dobbins — 15‑Day IL (Apr 30)

Lars Nootbaar — 60‑Day IL (May 26)

Ixan Henderson — 60‑Day IL (May 29)

Victor Santos — 60‑Day IL (Jun 1)

Injury Edge: Slightly Cardinals — Seattle is missing more MLB‑level contributors.

Probable Pitching Matchup

Seattle — George Kirby (RHP)

Record: 3–2

ERA: 2.97

WHIP: 1.05

K/BB: 27 / 8

HR Allowed: 4

St. Louis — Andre Pallante (RHP)

Record: 2–1

ERA: 4.05

WHIP: 1.45

K/BB: 12 / 11

HR Allowed: 2

Pitching Edge: Mariners — Kirby has been significantly sharper with elite command and efficiency.

Team Records & Recent Form

Seattle Mariners (11–15)

Last 5: W, L, L, W, W

Offense: .226 AVG, 101 R, 193 H, 25 HR, .320 OBP, .363 SLG

Pitching: 3.42 ERA (6th in MLB), 1.22 WHIP

St. Louis Cardinals (14–10)

Last 5: L, W, L, W, W

Offense: .228 AVG, 112 R, 182 H, 27 HR, .320 OBP, .372 SLG

Pitching: 4.77 ERA, 1.43 WHIP

Form Edge: Cardinals — stronger home performance (7–5) and more consistent run scoring.

Key Player Matchups

Seattle

Luke Raley: 5 HR, .292 AVG, 13 RBI

Randy Arozarena: .290 AVG, .385 OBP

Cal Raleigh: 14 RBI, 5 HR

St. Louis

Jordan Walker: 8 HR, .292 AVG, 16 RBI

Alec Burleson: 17 RBI

Matchup Note: Walker vs. Kirby is the marquee duel — Walker’s power vs. Kirby’s elite strike‑throwing.

Series & Trend Notes

Mariners rank 25th in runs per game (3.9).

Cardinals rank top‑10 in HR (27).

Game Odds

Seattle Mariners              – 163

St. Louis Cardinals           7.5

Odds Courtesy of Sports Odds Direct as of Thursday, April 23, 2026