MLB Game Preview: San Francisco Giants (6-12) vs. Cincinnati Reds (11-7)

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Cincinnati Reds logo

First Pitch: 9:40 AM PT / 12:40 PM ET

Venue: Great American Ball Park — Cincinnati, Ohio

Weather Outlook

Temperature: ~73°F at first pitch

Wind: ~14 mph SSW

Conditions: Partly cloudy, warm, slightly hitter‑friendly environment

Team Records & Recent Form

San Francisco Giants (6–12)

Last 5: L 8–3, L 2–1, L 6–2, L 6–2, W 6–3

Season stats:

.243 AVG, 55 R, 145 H, 9 HR, .287 OBP, .353 SLG

4.41 ERA, 1.40 WHIP, 72 BB, 158 K, .247 OBA

Cincinnati Reds (11–7)

Last 5: W 8–3, W 2–1, L 9–6, W 7–3, L 10–2

Season stats:

.207 AVG, 64 R, 122 H, 21 HR, .304 OBP, .346 SLG

3.81 ERA, 1.36 WHIP, 81 BB, 140 K, .232 OBA

Form Edge: Cincinnati — winners of two straight vs. SF and 6–4 in their last 10.

Injury Report

Giants

Sam Hentges (RP) — 15‑day IL, Apr 17

Joel Peguero (RP) — 15‑day IL, Apr 17

Harrison Bader (LF) — 10‑day IL, Apr 22

Parks Harber (3B) — 7‑day IL, Apr 27

Jared Oliva (OF) — 10‑day IL, Jun 1

Reds

Emilio Pagán (RP) — Day‑to‑day, Apr 16

Alex Young (RP) — OUT, Apr 16

Jose Trevino (C) — 10‑day IL, Apr 20

Josh Staumont (RP) — 7‑day IL, Apr 21

Nick Lodolo (SP) — 15‑day IL, Apr 24

Probable Starting Pitchers

San Francisco — RHP Landen Roupp (2–1, 3.24 ERA, 1.14 WHIP)

16.2 IP, 14 H, 18 K, 5 BB, 0 HR allowed

Road ERA: 0.75 in two starts

Cincinnati — RHP Chase Burns (1–1, 3.31 ERA, 1.29 WHIP)

16.1 IP, 13 H, 18 K, 8 BB, 3 HR allowed

Allowed 5 ER in last home start

Pitching Edge: Slightly San Francisco — Roupp has been excellent on the road and has dominated Reds hitters historically (.214 opponent AVG).

Key Player Matchups

Giants Hitters vs. Burns

Luis Arraez: .333 AVG vs. Burns (21–63)

Willy Adames: 3 HR, .257 AVG vs. Burns

Rafael Devers: .229 AVG vs. Burns

Matt Chapman: .271 AVG, 7 RBI vs. Burns

Reds Hitters vs. Roupp

Elly De La Cruz: 6 HR, 11 RBI, .282 AVG vs. Roupp

Sal Stewart: 7 HR, 17 RBI, .323 AVG vs. Roupp

Eugenio Suárez: 3 HR, 9 RBI vs. Roupp

Series History & Context

Reds lead the series 2–0 with wins of 2–1 and 8–3.

Stewart hit two 3‑run HRs on April 15.

Reds seeking a three‑game sweep.

Betting Trends

Reds have hit the Under in 27 of their last 50 home games (+8.2 units).

Giants rank 30th in MLB in runs per game (3.1).

Reds rank 26th (3.6).

Game Odds

San Francisco Giants      8

Cincinnati Reds                 – 131

Odds Courtesy of Sports Odds Direct as of Wednesday, April 15, 2026