MLB Game Preview: San Francisco Giants (24-15) vs. Minnesota Twins (19-20)

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Game Details

  • Date: Saturday, May 10, 2025
  • Time: 7:15 PM ET
  • Venue: Target Field, Minneapolis, MN
  • Broadcast: ESPN, Bally Sports North, NBC Sports Bay Area

The San Francisco Giants (24-15) take on the Minnesota Twins (19-20) in the second game of a three-game series at Target Field. The Twins secured a 3-1 victory in the series opener, extending their season-best six-game winning streak. San Francisco looks to bounce back and even the series, while Minnesota aims to continue their strong home form.

Team Form & Key Storylines

Twins’ Home Dominance

Minnesota has been exceptional at home, boasting a 13-6 record at Target Field. Their pitching staff has been solid, ranking sixth in MLB with 9.2 strikeouts per nine innings. The Twins have won seven straight home games, outscoring opponents by nine runs in their last ten contests.

Giants’ Road Performance

San Francisco has been strong on the road, holding a 12-10 away record. Their offense has been productive, ranking sixth in the NL with 40 home runs. However, they struggled against Chris Paddack’s dominant pitching in Game 1, managing just one run on three hits.

Head-to-Head History

This is the second meeting of the season between these teams. The Twins took the series opener, but San Francisco has historically performed well against Minnesota, winning five of their last ten matchups.

Key Matchups to Watch

Byron Buxton vs. Giants Pitching

Buxton has been Minnesota’s offensive leader, recording 17 extra-base hits (five doubles, three triples, nine home runs). His ability to drive in runs and create scoring opportunities will be crucial for the Twins.

Jung Hoo Lee vs. Twins Pitching

Lee has been one of San Francisco’s most consistent hitters, tallying 11 doubles, two triples, four home runs, and 23 RBIs. His ability to get on base and generate offense will be key for the Giants.

Starting Pitchers: Logan Webb vs. Joe Ryan

  • Giants:Logan Webb (4-2, 2.61 ERA, 56 strikeouts in 48.1 innings)
    • Webb has been dominant, ranking No. 1 in MLB with a 2.95 FIP since 2021.
    • He pitched seven innings of one-run ball in his last outing against Colorado.
  • Twins: Joe Ryan (2-2, 4.26 ERA, 38 strikeouts in 38 innings)
  • Ryan has been solid, allowing two runs or fewer in each of his last three starts.

Game Odds

San Francisco Giants      7

Minnesota Twins             – 115

Odds Courtesy of Sports Odds Direct as of Friday, May 9, 2025

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