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MLB Game Preview: San Diego Padres (16-6) vs. Detroit Tigers (13-9)

The San Diego Padres (16-6) and Detroit Tigers (13-9) are set to open a three-game interleague series on Monday, April 21, 2025, at Comerica Park in Detroit. Both teams enter the matchup as division leaders, making this a compelling battle between two strong contenders.

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Game Details

  • Date: Monday, April 21, 2025
  • Time: 6:40 PM ET
  • Venue: Comerica Park, Detroit
  • TV Broadcast: Bally Sports Detroit, Bally Sports San Diego
  • Series Status: Game 1 of 3

Team Overview & Key Players

San Diego Padres (16-6, 1st in NL West)

The Padres have been one of the most dominant teams in the National League, leading MLB with a .346 team on-base percentage. Their pitching staff has also been elite, ranking second in MLB with a 2.74 ERA.

Key Players

  • Fernando Tatis Jr. (RF) – Leads the team with eight home runs and 10 extra-base hits.
  • Manny Machado (3B) – A consistent force at the plate, hitting .275 with five home runs.
  • Luis Arraez (1B) – Batting .274 with two home runs over his last 10 games.
  • Randy Vasquez (SP) – Set to start; holds a 1-1 record with a 1.74 ERA.

Detroit Tigers (13-9, 1st in AL Central)

The Tigers have been strong at home, boasting an 8-2 record at Comerica Park. Their offense ranks 11th in MLB with a .246 team batting average, while their pitching staff has a 2.66 ERA over the last 10 games.

Key Players

  • Spencer Torkelson (1B) – Leads Detroit with seven home runs and 21 RBIs.
  • Kerry Carpenter (OF) – Batting .288 with two doubles and a home run over his last 10 games.
  • Keider Montero (SP) – Set to start; holds a 0-1 record with a 9.00 ERA.

Game 1 Pitching Matchup

PitcherTeamRecordERALast Start
Randy VasquezPadres1-11.745.0 IP, 1 ER vs. Cubs
Keider MonteroTigers0-19.005.0 IP, 5 ER vs. Brewers

Vasquez has been solid in his first few starts, while Montero is looking to bounce back from a rough outing against Milwaukee.

Game Outlook & Predictions

  • Padres’ Strategy: Expect San Diego to rely on power hitting, with Tatis Jr. and Machado leading the charge.
  • Tigers’ Adjustments: Detroit must limit home runs and capitalize on scoring opportunities against Vasquez.
  • X-Factor: Spencer Torkelson’s ability to drive in runs could be the difference-maker.

Game Odds

San Diego Padres                             8

Detroit Tigers                                    – 130

Odds Courtesy of Sports Odds Direct as of Sunday, April 20, 2025

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