MLB Game Preview: Pittsburgh Pirates (14-11) vs. Milwaukee Brewers (13-11)

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Milwaukee Brewers logo

Venue: American Family Field — Milwaukee, WI

First Pitch is scheduled for 7:40 PM ET (4:40 PM PT)

Coverage: ESPN Unlimited / MLB.TV

Weather Outlook — Milwaukee, WI

Temperature: ~68°F at game time

Conditions: Mild, partly cloudy

Impact: Neutral hitting environment; roof may be closed depending on conditions.

Injury Report

Pittsburgh Pirates

Dominic Fletcher — 7‑Day IL (Apr 25)

Anthony Solometo — 7‑Day IL (May 1)

Jared Triolo — 10‑Day IL (May 1)

Jared Jones — 60‑Day IL (May 25)

Sean Sullivan — 60‑Day IL (Jun 1)

Milwaukee Brewers

J.B. Bukauskas — 7‑Day IL (Apr 26)

Jackson Chourio — 10‑Day IL (May 1)

Jared Koenig — 15‑Day IL (May 3)

Quinn Priester — 15‑Day IL (May 8)

Andrew Vaughn — 10‑Day IL (May 12)

Injury Edge: Slightly Brewers — Pirates have more long‑term pitching losses.

Probable Pitching Matchup

Pittsburgh — Paul Skenes (RHP)

Record: 3–1

ERA: 3.27

WHIP: 0.91

K/BB: 23 K / 7 BB

HR Allowed: 2

Milwaukee — Brandon Woodruff (RHP)

Record: 2–0

ERA: 3.42

WHIP: 0.93

K/BB: 20 K / 4 BB

HR Allowed: 3

Pitching Edge: Slightly Pirates — Skenes’ elite WHIP and strikeout profile give him a narrow advantage.

Team Records & Recent Form

Pittsburgh Pirates (14–11)

Last 5: L, W, L, W, L

Team Stats: .250 AVG, 122 R, 27 HR, .335 OBP, .391 SLG, 3.33 ERA (3rd in MLB)

Road Record: 6–6

Milwaukee Brewers (13–11)

Last 5: L, L, W, L, W

Team Stats: .239 AVG, 120 R, 19 HR, .342 OBP, .366 SLG, 3.93 ERA

Home Record: 7–5

Form Edge: Even — both teams alternating wins and losses.

Key Player Matchups

Pittsburgh

Oneil Cruz: 8 HR, .284 AVG, 23 RBI

Ryan O’Hearn: .325 AVG, .417 OBP, .513 SLG

Milwaukee

Brice Turang: .280 AVG, 18 RBI, 4 HR

William Contreras: .291 AVG, .371 OBP

Matchup Note: Cruz vs. Woodruff is the marquee duel — elite power vs. elite command.

Series & Trend Notes

Brewers rank 7th in MLB in runs scored (124).

Pirates rank 10th in HR (27) and 11th in AVG (.250).

Game Odds

Pittsburgh Pirates            – 136

Milwaukee Brewers       7

Odds Courtesy of Sports Odds Direct as of Thursday, April 23, 2026