MLB Game Preview: Milwaukee Brewers (48-29) vs. Cincinnati Reds (37-41)

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Cincinnati Reds logo

CINCINNATI – The Milwaukee Brewers continue their division road swing Wednesday night when they face the Cincinnati Reds at Great American Ball Park. First pitch is scheduled for 7:10 p.m. ET, with Cooper Drohan set to start for Milwaukee against Rhett Lowder for Cincinnati.

Milwaukee enters at 48–29, holding one of the National League’s best records and looking to extend its lead in the NL Central. Cincinnati, at 37–41, is trying to stay within striking distance of the Wild Card race after an inconsistent June.

Venue

Great American Ball Park — Cincinnati, Ohio

First pitch: 7:10 p.m. ET

Surface: Natural grass

Dimensions: 328–404–325 (one of MLB’s most hitter‑friendly parks)

Weather

  • Temperature: 81°F
  • Wind: 9 mph blowing out to right-center
  • Humidity: 68%
  • Chance of rain: 15%

Conditions favor hitters, especially left‑handed power.

Probable Pitchers

Milwaukee: LHP Cooper Drohan

Drohan has shown steady improvement, leaning on a mid‑90s fastball and a sharp slider. His strikeout rate has climbed in June, but he has struggled at times with walks and deep counts. This will be his first career start at Great American Ball Park.

Cincinnati: RHP Rhett Lowder

Lowder has been one of Cincinnati’s most reliable young arms, featuring a heavy sinker and strong ground‑ball profile. He has been particularly effective at home, allowing two runs or fewer in four of his last five starts in Cincinnati.

Injury Report

Milwaukee Brewers

  • Christian Yelich — ACTIVE
  • William Contreras — ACTIVE
  • Rhys Hoskins — ACTIVE
  • Jackson Chourio — OUT (quad)
  • DL Hall — OUT (knee)

Cincinnati Reds

  • Elly De La Cruz — ACTIVE
  • Spencer Steer — ACTIVE
  • Jeimer Candelario — ACTIVE
  • Hunter Greene — OUT (shoulder)
  • TJ Friedl — OUT (hamstring)

Team Records & Recent Form

Milwaukee Brewers (48–29)

  • Last 10: 7–3
  • Trend: Offense surging; rotation stabilizing
  • Strength: Plate discipline, bullpen depth
  • Weakness: Occasional defensive lapses

Cincinnati Reds (37–41)

  • Last 10: 4–6
  • Trend: Pitching competitive; offense inconsistent
  • Strength: Speed, athleticism, home‑run potential
  • Weakness: Strikeout rate, bullpen volatility

Key Player Matchups

Elly De La Cruz (CIN) vs Cooper Drohan (MIL)

De La Cruz’s elite bat speed and ability to hit left‑handed pitching make him Cincinnati’s most dangerous weapon. Drohan’s slider away will be the key pitch.

Christian Yelich (MIL) vs Rhett Lowder (CIN)

Yelich has strong splits against sinker‑heavy right‑handers. Lowder must keep the ball down to avoid damage in a hitter‑friendly park.

William Contreras (MIL) vs Reds Bullpen

Contreras’ ability to hit late‑inning velocity gives Milwaukee a major advantage if the game is close.

Series History

  • Season series: Brewers lead 3–2
  • At Great American Ball Park: Brewers have won 8 of last 12
  • Recent trend: Milwaukee has outscored Cincinnati 27–19 across their last six meetings

Betting Trends

Milwaukee Brewers

  • 6–2 in last eight road games
  • Over has hit in 5 of last 7
  • 5–1 in Drohan’s last six starts

Cincinnati Reds

  • 4–1 in Lowder’s last five home starts
  • Under has hit in 6 of last 9
  • 3–7 in last 10 vs teams above .500

Game Odds

Milwaukee Brewers       – 126

Cincinnati Reds                 9.5

Odds Courtesy of Sports Odds Direct as of Tuesday, June 23, 2026

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