First pitch 9:40 p.m. ET (6:40 p.m. PT)
Venue: T-Mobile Park, Seattle, Washington
This is the opener of a four-game series between two AL West clubs playing out the final week of the regular season. The Angels sit last in the division with a poor overall record and weak road mark. The Mariners are third in the AL West, still mathematically alive for a long-shot postseason push or better seeding positioning, and they hold a solid home record.
Starting Pitchers
Angels: RHP Grayson Rodriguez (4-8, 5.96 ERA, 1.54 WHIP, 83 K in 93.2 IP over 19 starts). Rodriguez has battled inconsistency and elevated run prevention numbers this season after previous promise.
Mariners: RHP Bryan Woo (12-9, 3.92 ERA, 1.08 WHIP, 167 K in 167.2 IP over 29 starts). Woo has been a reliable innings-eater with strong control and strikeout ability, posting solid recent form including scoreless or low-run outings.
Woo holds a clear advantage in ERA, WHIP, strikeouts, and overall reliability against Rodriguez’s higher ERA and walk issues.
Current Weather Forecast (T-Mobile Park / Seattle)
Mostly cloudy with a slight chance of rain or showers, high near 61-62°F during the day, cooling into the mid-to-upper 50s by first pitch. Light north/northeast winds around 5-8 mph. Humidity moderate to high; possible light precipitation later in the evening. Roof status may be considered depending on conditions (T-Mobile Park has a retractable roof). Cool, typical late-September Pacific Northwest evening.
Injury Reports
Angels (notable):
Nolan Schanuel (1B, side/intercostal), Kyren Paris (2B, finger), Gustavo Campero (OF, hamstring) – 10-day IL.
Samy Natera Jr. (P, forearm), George Klassen (P, back) – 15-day IL.
Longer-term: Yoan Moncada (3B, knee), Jack Kochanowicz (P, elbow), Anthony Rendon (3B, hip), others on 60-day IL.
Mariners (notable):
Emerson Hancock (SP, groin), Cole Wilcox (RP, oblique) – 15-day IL.
Brendan Donovan (INF, head/concussion) – 7-day IL.
Longer-term: Luke Raley (OF, elbow), Colt Emerson (INF, wrist), Matt Brash (RP, lat), Will Wilson (INF, thumb), Nick Davila (P, shoulder), and several others on 60-day IL. Andres Muñoz has been day-to-day with a leg issue in some reports.
Both teams are dealing with significant absences that thin depth, particularly in the Angels’ position-player group and the Mariners’ bullpen/rotation depth.
Key Player vs. Player Matchups / Notable Performers
Zach Neto / Mike Trout / Wade Meckler (Angels) – Neto provides power and production from shortstop; Trout remains a threat when healthy; Meckler has shown recent contact ability.
Randy Arozarena / Julio Rodríguez / Cal Raleigh / Dominic Canzone / J.P. Crawford (Mariners) – Arozarena leads in average and power; Rodríguez offers speed and contact; Raleigh and Canzone add middle-order pop; Crawford sets the table.
Woo’s strong command and strikeout stuff vs. the Angels’ lower-powered, strikeout-prone lineup will be key, while Rodriguez must limit damage against Seattle’s more balanced attack.
Recent Team Forms
Angels: Roughly 1-4 or 4-6 in recent stretches; poor road performance (26-51 range) and low run production overall.
Mariners: Around 3-2 or 5-5 in last 5-10; better at home (41-36 range) with recent wins including an extra-innings victory over Houston.
Series History (2026)
Mariners hold a slight edge in the season series (reports around 5-4). Competitive earlier matchups have featured both low-scoring pitching duels and higher-output games. This begins the final series between the clubs.
Betting Trends
Unders have been relevant in cooler Pacific Northwest nights and with Woo’s efficiency. Public money leans heavily toward the Mariners as favorites.
Game Odds
Los Angeles Angels 7
Seattle Mariners – 200
Odds Courtesy of Sports Odds Direct as of Wednesday, September 23, 2026
