MLB Game Preview: Cincinnati Reds (16-8) vs. Tampa Bay Rays (12-11)

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Tampa Bay Rays

First Pitch: 1:10 PM ET

Venue: Tropicana Field, One Tropicana Drive, St. Petersburg, FL

Weather Outlook — St. Petersburg, FL

Temperature: ~80°F at gametime

Wind: ~11 mph E

Hourly trend: 77° at 4 PM → 82° by 7 PM

Injury Report

Cincinnati Reds

Nick Lodolo (finger) — threw 50 pitches in simulated game, trending toward return.

Tampa Bay Rays

Josh Staumont (RP) — 7‑Day IL

Alex Young (RP) — OUT

José Trevino (C) — 10‑Day IL

Nick Lodolo (SP) — 15‑Day IL (listed on ESPN injury feed)

Caleb Ferguson (RP) — 15‑Day IL

Team Records & Recent Form

Cincinnati Reds (16–8)

Away Record: 10–2

Streak: W5 (swept MIN, won first two vs TB)

Recent Scores: 12–6 W, 6–1 W, 7–4 W, 5–4 W, 2–1 W

Team Stats:

4.0 runs/game

.207 AVG

27 HR

3.47 ERA

.227 OAV

Tampa Bay Rays (12–11)

Home Record: 4–4

Streak: L3 (two losses to CIN, one to PIT)

Recent Scores: 6–12 L, 1–6 L, 3–6 L, 8–7 W, 1–5 L

Team Stats:

4.8 runs/game

.255 AVG

19 HR

4.86 ERA

.232 OAV

Probable Pitching Matchup

Cincinnati — Brandon Williamson (LHP)

2–1, 4.35 ERA, 1.35 WHIP

20.2 IP, 15 H, 12 K, 13 BB, 3 HR allowed

Tampa Bay — Nick Martinez (RHP)

0–1, 2.45 ERA, 1.23 WHIP

22.0 IP, 20 H, 14 K, 7 BB, 3 HR allowed

Key Player Matchups

Cincinnati Reds

Elly De La Cruz: 3‑for‑6, 2 HR, 5 RBI, SB, 3 R on Apr 21 — explosive form.

Sal Stewart: .299 AVG, 24 RBI — team leader.

Chase Burns: 2.57 ERA — rotation anchor.

Tampa Bay Rays

Jonathan Aranda: HR + 3 RBI on Apr 21.

Junior Caminero: 5 HR, .261 AVG — primary power threat.

Chandler Simpson: .323 AVG — table‑setter.

Series History

Reds lead the current series 2–0, winning 6–1 and 12–6.

Reds have won five straight overall; Rays have lost three straight.

Betting Trends

Reds: W5, averaging 6.4 runs/game during streak (inference from scores).

Rays: L3, allowing 24 runs in last two games.

Reds bullpen: 76.9% save rate, 20 holds (2nd in MLB).

Game Odds

Cincinnati Reds                 8.5

Tampa Bay Rays                – 143

Odds Courtesy of Sports Odds Direct as of Tuesday, April 21, 2026