Venue, Date & Start Time
Location: Chase Field, Phoenix, AZ
First Pitch: 6:40 PM local time
Weather Outlook (Phoenix, AZ)
Temperature: 86°F at gametime
Wind: Light W winds (approx. 12 mph)
Conditions: Warm, dry desert air — typically hitter‑friendly unless roof is closed
Injury Report
Chicago White Sox
Chris Murphy (RP) — 15‑Day IL, returns Apr 23
Austin Hays (LF) — 10‑Day IL, returns Apr 24
Jonathan Cannon (SP) — 15‑Day IL, returns Apr 28
Kyle Teel (C) — 10‑Day IL, returns May 1
Prelander Berroa (RP) — 60‑Day IL, returns May 24
Arizona Diamondbacks
Carlos Santana (1B) — 10‑Day IL, returns Apr 24
Gabriel Moreno (C) — 10‑Day IL, returns Apr 25
Tyler Locklear (1B) — 10‑Day IL, returns May 18
Pavin Smith (1B) — 60‑Day IL, returns May 29
Cristian Mena (RP) — 60‑Day IL, returns Jun 1
Probable Pitching Matchup
Chicago — LHP Anthony Kay (1–0, 2.60 ERA)
WHIP: 1.27
IP: 17.1 | H: 13 | K: 12 | BB: 9 | HR: 2
Arizona — LHP Eduardo Rodriguez (1–0, 1.96 ERA)
WHIP: 1.22
IP: 23.0 | H: 19 | K: 14 | BB: 9 | HR: 2
Pitching Edge: Diamondbacks, with Rodriguez carrying a sub‑2.00 ERA and stronger command profile.
Team Records & Recent Form
Chicago White Sox (9–14)
Last 5: W 11–5, W 7–4, L 7–6 (F/11), W 9–2, L 5–3
Season Stats:
AVG: .218
Runs: 93
HR: 28
OBP: .312
ERA: 4.84
WHIP: 1.46
Arizona Diamondbacks (13–10)
Last 5: L 11–5, L 10–4, W 6–2, W 6–3, W 8–5 (F/10)
Season Stats:
AVG: .242
Runs: 104
HR: 20
OBP: .297
ERA: 4.32
WHIP: 1.30
Key Player Matchups
Chicago Hitters
Munetaka Murakami: 9 HR, 17 RBI, .234 AVG (team HR & RBI leader)
Chase Meidroth: .253 AVG, .344 OBP (team batting leader)
Arizona Hitters
Corbin Carroll: .288 AVG, .391 OBP, .575 SLG, 16 RBI (team offensive engine)
Ketel Marte: 4 HR, 9 RBI
Matchup Lens: Chicago brings more raw power (28 HR vs. Arizona’s 20), but Arizona has the more efficient contact and on‑base profile.
Series History & Context
4/21: White Sox beat Diamondbacks 11–5 behind a breakout offensive performance.
White Sox lead the series 1–0.
Arizona has lost two straight after a three‑game win streak.
Game Odds
Chicago White Sox 9.5
Arizona Diamondbacks – 156
Odds Courtesy of Sports Odds Direct as of Tuesday, April 21, 2026
