MLB Game Preview: Chicago White Sox (22-44) vs. Houston Astros (36-29)

The Chicago White Sox (22-44) travel to Daikin Park to face the Houston Astros (36-29) in the first game of a three-game series on Tuesday, June 10, 2025. The Astros return home after a 4-2 road trip, while the White Sox aim to build momentum following a seven-game homestand.

Game Details

• Matchup: Chicago White Sox vs. Houston Astros
• Date: Tuesday, June 10, 2025
• Time: 8:10 PM ET
• Venue: Daikin Park (Houston, TX)
• Broadcast: Space City Home Network, 790 AM, 93.3 FM

Team Breakdown & Key Players

Chicago White Sox (22-44)

• Last Game: The White Sox split a four-game series with the AL Central-leading Tigers and won two of three against the Royals.
• Key Players:
  • Miguel Vargas (3B) – Leads the team with nine home runs and 29 RBI, ranking 65th in MLB in homers.
  • Chase Meidroth (SS) – Batting .299, with five doubles and two home runs.
  • Shane Smith (SP) – Expected starter with a 2-3 record and 2.45 ERA, looking to build on his 5 1/3 scoreless innings in his last outing.
• Strengths: Young talent, aggressive baserunning.
• Weaknesses: Road struggles, pitching inconsistency.

Houston Astros (36-29)

• Last Game: The Astros lost 4-2 to the Guardians, but won the first two games of the series.
• Key Players:
  • Jeremy Peña (SS) – Batting .316, with nine home runs and 32 RBI, ranking 65th in MLB in homers.
  • Isaac Paredes (3B) – Provides power with 14 home runs and 38 RBI, ranking 14th in MLB in homers.
  • Lance McCullers Jr. (SP) – Expected starter with a 1-1 record and 4.44 ERA, looking for his second win since 2022.
• Strengths: Home-field advantage, strong bullpen.
• Weaknesses: Strikeout rate, occasional defensive lapses.

Matchup Analysis & Betting Insights

• Head-to-Head: The Astros have won two of three matchups against the White Sox this season.
• Game Strategy:
  • White Sox: Need Smith to limit runs while relying on their young hitters.
  • Astros: Must capitalize on Chicago’s pitching struggles and generate early offense.

Game Odds

Chicago White Sox          7.5

Houston Astros                 – 175

Odds Courtesy of Sports Odds Direct as of Monday, June 9, 2025