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MLB Game Preview: Chicago White Sox (10-26) vs. Kansas City Royals (21-16)

Date: May 7, 2025
Time: 7:40 PM ET
Venue: Kauffman Stadium, Kansas City, MO
Broadcast: NBC Sports Chicago, Bally Sports Kansas City

Matchup Overview

The Chicago White Sox (10-26) and Kansas City Royals (21-16) meet for the third game of their four-game series, with Kansas City holding a 2-0 series lead after a 4-3 walk-off victory on Tuesday night. The Royals have now won nine straight games at Kauffman Stadium against the White Sox, their longest home winning streak against Chicago in franchise history.

Starting Pitchers

Chicago White Sox – Jonathan Cannon (2-3, 4.26 ERA, 5.35 K/9)

  • Last Start: 6 innings, 2 earned runs vs. Houston.
  • Season Stats: 4.26 ERA, 1.38 WHIP, .267 opponent batting average.
  • Analysis: Cannon has struggled on the road, posting a 6.35 ERA in away games. He’ll need to limit Kansas City’s aggressive hitters to keep Chicago competitive.

Kansas City Royals – Michael Wacha (1-4, 3.52 ERA, 7.1 K/9)

  • Last Start: 6 innings, 1 earned run vs. Cleveland.
  • Season Stats: 3.52 ERA, 1.19 WHIP, .232 opponent batting average.
  • Analysis: Wacha has been solid despite his losing record, keeping opponents off balance with his changeup. He posted a 1.33 ERA in four starts against the White Sox last season.

Key Players to Watch

Chicago White Sox

  • Luis Robert Jr. – Batting .231 with six home runs, looking to spark Chicago’s offense.
  • Miguel Vargas12-for-38 over his last 10 games, providing consistency.
  • Josh Rojas – Delivered an RBI single in Game 2, continuing his strong season.

Kansas City Royals

  • Bobby Witt Jr. – Hit the game-winning RBI single in Game 2, proving clutch.
  • Salvador Perez – Batting .285 with seven home runs, leading Kansas City’s offense.
  • Maikel Garcia – Has six stolen bases, adding speed to the Royals’ lineup.

Game Storylines & Predictions

1. Can Chicago End Its Losing Streak in Kansas City?

The White Sox have lost nine straight games at Kauffman Stadium, their longest road losing streak against the Royals. They’ll need a strong pitching performance from Cannon to break the trend.

2. Royals’ Home Dominance

Kansas City has been 13-5 at home, using their pitching depth to control games. If Wacha dominates, they could extend their winning streak.

3. Pitching Duel – Cannon vs. Wacha

Cannon has struggled on the road, while Wacha has historically pitched well against Chicago. If Wacha limits baserunners, Kansas City should take Game 3.

Game Odds

Chicago White Sox          8

Kansas City Royals           – 225

Odds Courtesy of Sports Odds Direct as of Tuesday, May 6, 2025

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