MLB Game Preview: Chicago Cubs (47-33) vs. St. Louis Cardinals (44-37)

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St. Louis Cardinals logo

With the Cardinals holding a 2–1 series lead, the Cubs aim to even the set and maintain their slim division lead.

Game Details

  • Matchup: Chicago Cubs (47–33) vs. St. Louis Cardinals (44–37)
  • Venue: Busch Stadium, St. Louis, MO
  • Time: 2:15 PM ET
  • Broadcast: Marquee Sports Network, Bally Sports Midwest

Starting Pitchers

Cubs: Shota Imanaga (3–2, 2.82 ERA)

Returning from a hamstring injury, Imanaga makes his first start since early May. The Japanese lefty was dominant before the setback, posting a 2.82 ERA with 34 strikeouts in 38.1 innings. His deceptive fastball and pinpoint control will be tested against a red-hot Cardinals lineup.

Cardinals: Andre Pallante (5–3, 4.48 ERA)

Pallante has been steady in the rotation, though he’s allowed 3+ earned runs in three of his last four starts. He’ll need to keep the ball down against a Cubs team that ranks top-5 in slugging vs. right-handed pitching.

Players to Watch

Chicago Cubs

  • Pete Crow-Armstrong: Batting .272 with 21 HRs, 61 RBIs, and 20 doubles. He’s the Cubs’ most dynamic offensive weapon.
  • Kyle Tucker: 15-for-36 over his last 10 games with 3 HRs and 3 doubles.
  • Seiya Suzuki: Launched a 3-run homer earlier in the series and is heating up at the plate.

St. Louis Cardinals

  • Nolan Arenado: 10 HRs, 11 doubles, and a .255 average. A proven clutch performer in rivalry games.
  • Alec Burleson: 12-for-41 with 4 HRs in his last 10 games.
  • Masyn Winn: Hit a 2-run homer in Game 2 and continues to impress with his glove and bat.

Key Stats & Trends

  • Cubs are 22–18 on the road, but have lost 5 of their last 6 games.
  • Cardinals are 26–16 at home and have won 7 of their last 8 overall.
  • Over has hit in 2 of the 3 games in this series so far.
  • Cubs rank 3rd in MLB in team batting average (.256); Cardinals are 4th in the NL (.255).

Game Odds

Chicago Cubs                     – 137

St Louis Cardinals            9

Odds Courtesy of Sports Odds Direct as of Wednesday, June 25, 2025

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MLB Editor
Profile: A dedicated Major League Baseball analyst with a comprehensive understanding of the sport’s strategic, statistical, and developmental layers. This columnist delivers in‑depth coverage that blends advanced metrics, scouting insight, and historical context to illuminate the trends shaping today’s game. Background: With extensive experience following MLB at both the team and league levels, the columnist has contributed to national sports outlets, digital platforms, and radio segments focused on roster construction, player evaluation, and organizational philosophy. A background in sports journalism and analytics supports a disciplined approach to breaking down performance, interpreting data, and tracking long‑term competitive cycles. Signature Coverage Areas: Game previews and pitching‑matchup analysis Advanced statistical breakdowns and sabermetric insights Prospect evaluation, farm‑system trends, and player development Trade‑deadline movement, free‑agency analysis, and front‑office strategy Historical context and postseason features Style & Approach: The writing emphasizes clarity, accuracy, and accessibility — translating complex data and tactical nuance into insights that resonate with both traditional fans and analytically minded readers. Each column reflects a commitment to balanced reporting, thoughtful evaluation, and a deep appreciation for the evolving landscape of Major League Baseball.