Game Details
- Matchup: Chicago Cubs (46–33) vs. St. Louis Cardinals (44–36)
- Date: Wednesday, June 25, 2025
- First Pitch: 7:45 PM ET
- Venue: Busch Stadium, St. Louis, MO
- Broadcast: Marquee Sports Network, Bally Sports Midwest, MLB.TV
Game Context & Series Recap
The Cardinals have taken the first two games of this three-game set, including a thrilling 8–7 win on Tuesday. St. Louis has now won 8 of its last 10 games, while the Cubs have dropped 5 of their last 6, despite entering the series atop the NL Central.
This is the third meeting of the season between the two clubs, with St. Louis holding a 2–0 edge. The Cubs are looking to avoid a sweep and regain momentum heading into a weekend series against Houston.
Probable Pitchers
Chicago Cubs: Matthew Boyd (6–3, 2.84 ERA)
- 85.2 IP, 79 K, 1.14 WHIP
- Coming off 5 IP, 2 ER vs. Seattle
- 10 quality starts in 15 outings
- 1–1 with a 2.12 ERA in 3 career starts vs. Cardinals
St. Louis Cardinals: Erick Fedde (3–6, 3.54 ERA)
- 84.2 IP, 55 K, 1.30 WHIP
- Last start: 5 IP, 1 ER vs. White Sox
- 6 quality starts in 15 appearances
- 0–1 with a 6.33 ERA in 4 career appearances vs. Cubs
Players to Watch
Chicago Cubs
- Pete Crow-Armstrong: 21 HR, 60 RBI – 3-game hitting streak
- Seiya Suzuki: 2 HR, 3 RBI in last 5 games – 21 HR on the season
- Nico Hoerner: .294 AVG – team leader in batting average
St. Louis Cardinals
- Brendan Donovan: .310 AVG – 87 hits, team’s most consistent bat
- Willson Contreras: 10 HR, 50 RBI – leads team in both categories
- Lars Nootbaar: 11 HR – 4-game hitting streak entering Wednesday
Team Stats & Trends
| Category | Cubs | Cardinals |
|---|---|---|
| Record | 46–33 | 44–36 |
| Road/Home Record | 21–18 (road) | 26–15 (home) |
| Team ERA | 3.89 (16th MLB) | 3.90 (17th MLB) |
| Batting Average | .255 (7th MLB) | .255 (6th MLB) |
| Runs Scored | 426 (2nd MLB) | 374 (7th MLB) |
| Home Runs | 113 (4th MLB) | 78 (20th MLB) |
The Cubs are 28–11 when favored by –131 or more. The Cardinals are 7–1 in their last 8 games overall.
Matthew Boyd’s consistency and the Cubs’ offensive firepower give them the edge in a close contest. Expect a bounce-back performance from Chicago’s bullpen and a strong outing from Pete Crow-Armstrong.
How to Watch Cubs vs Cardinals – June 25, 2025
- TV Channels: Marquee Sports Network (Cubs), Bally Sports Midwest (Cardinals)
- Streaming: MLB.TV, FuboTV (regional restrictions may apply)
- Radio: 670 The Score (Cubs), KMOX 1120 AM (Cardinals)
Game Odds
Chicago Cubs – 155
St. Louis Cardinals 8.5
Odds Courtesy of Sports Odds Direct as of Tuesday, June 24, 2025
