Venue & Event Details
Location: Notre Dame Stadium, South Bend, IN
Kickoff: 3:30 PM EST
Broadcast: NBC / Peacock
Weather Forecast
Temperature: 47°F at kickoff, dropping into low 40s by evening
Conditions: Cloudy skies, winds 10–12 mph
Impact: Passing efficiency may be slightly challenged; rushing and short-yardage execution favored
Injury Report
Syracuse: QB Rickie Collins (probable, 85 yards, 2 INTs vs Miami); RB Yasin Willis (healthy, 558 yards, 4 TDs); WR Johntay Cook II (healthy, 518 yards, 2 TDs).
Notre Dame: QB CJ Carr (healthy, 2,487 yards, 21 TDs, 6 INTs, 67.3% completion); RB Jeremiyah Love (healthy, 1,135 yards, 14 TDs); WR Malachi Fields (healthy, 596 yards, 5 TDs).
Key Player Matchups
CJ Carr (Notre Dame QB) vs Syracuse Secondary: Carr’s efficiency and poise will test a defense ranked 124th nationally in pass defense (267.1 YPG allowed).
Jeremiyah Love (Notre Dame RB) vs Syracuse Front Seven: Love’s explosive rushing (7 yards per carry) against a unit allowing 163.5 rushing YPG (95th nationally).
Johntay Cook II (Syracuse WR) vs Notre Dame CBs: Cook is Syracuse’s top playmaker but faces a defense ranked 17th nationally in scoring defense (18.4 PPG allowed).
Recent Team Forms
Syracuse: Lost 38–10 vs Miami (Nov. 8); offense struggled with only 85 passing yards.
Notre Dame: Beat Pittsburgh 37–15 (Nov. 15); Carr threw for 212 yards and 2 TDs, Love rushed for 147 yards and 1 TD.
Series History
All-time: Notre Dame leads 7–3 vs Syracuse.
Last meeting: Notre Dame won 41–24 in 2022 at the Carrier Dome.
Betting Trends:
Syracuse is 1–4 in last 5 games.
Notre Dame is 4–1 in last 5 games.
Overs have hit in 3 of last 5 Notre Dame games.
Historical Betting Results
Notre Dame has covered in 4 of last 6 games.
Syracuse has failed to cover in 3 of last 5 games.
Notre Dame has won 5 of last 6 head-to-head matchups.
Prediction: Notre Dame 45 – Syracuse 13
Game Odds
Syracuse Orange 50.5
Notre Dame Fighting Irish – 36.5
Odds Courtesy of Sports Odd Direct as of Friday, November 21, 2025
