FBS-CFB Game Preview: Oklahoma Sooners (5-1) vs. South Carolina Gamecocks (3-3)

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Venue & Game Details

Location: Williams-Brice Stadium, Columbia, SC

Kickoff: 12:45 p.m. ET

Conference: SEC inter-divisional matchup

Broadcast: SEC Network / Fubo streaming

Weather Forecast: Columbia, SC – ~71°F at kickoff, partly cloudy, winds 6–10 mph,

Team Recent Form

Oklahoma Sooners:

Wins: SMU, Houston, Tennessee, Auburn, Missouri

Loss: Texas (23–6, Red River Rivalry)

Trend: Strong defense, but QB John Mateer struggled vs. Texas with 3 INTs.

South Carolina Gamecocks:

Wins: Kentucky, Akron, Vanderbilt

Losses: LSU (20–10), Alabama, Georgia

Trend: Offense ranks 123rd nationally (310 YPG), but defense is solid (19.0 PPG allowed, 32nd FBS).

Injury Report

Oklahoma:

QB John Mateer – Probable (hand soreness)

WR Isaiah Sategna – Probable (hamstring)

South Carolina:

QB LaNorris Sellers – Probable (ankle)

WR Vandrevius Jacobs – Questionable (ankle)

Key Player Matchups

QB John Mateer (OU): 1,417 yards, 6 TDs, 6 INTs – must rebound against a defense that thrives on turnovers.

WR Isaiah Sategna (OU): 420 yards, 3 TDs – deep threat vs. SC’s secondary.

QB LaNorris Sellers (SC): 1,010 yards, 4 TDs, 2 INTs – dual-threat but inconsistent.

RB Rahsul Faison (SC): 231 yards, 3 TDs – faces OU’s 10th-ranked rush defense (84.8 YPG allowed).

DL Dylan Stewart (SC): 3.5 sacks, 9 TFL – key to pressuring Mateer.

Series History

This is the second-ever meeting between Oklahoma and South Carolina.

In 2024, South Carolina stunned OU in Norman 35–9, sparking a late-season turnaround.

Betting Trends:

Oklahoma is 5-1 ATS this season.

South Carolina is 3-3 ATS.

The Under has hit in 4 of OU’s 6 games.

South Carolina is 2-1 at home this season.

Historical Betting Results

OU has covered in 5 of 6 games in 2025.

South Carolina is 1-3 ATS in SEC play.

Average margin in OU’s wins: +18.6 points.

Game Odds

Oklahoma Sooners                         – 4

South Carolina Gamecocks          42.5

Odds Courtesy of Sports Odd Direct as of Friday, October 17, 2025