FBS-CFB Game Preview: Michigan State Spartans (3-3) vs. Indiana Hoosiers (6-0)

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Venue & Game Details

Location: Memorial Stadium, Bloomington, IN

Kickoff: 3:30 p.m. ET

Conference: Big Ten East vs. Big Ten East

Broadcast: Peacock (streaming)

Weather Forecast: Bloomington, IN – ~63°F at kickoff, partly cloudy, winds 6–10 mph,

Team Recent Form

Indiana Hoosiers:

Wins: Oregon (30–20), Iowa (20–15), Illinois (63–10), Old Dominion, Kennesaw State, Indiana State

Trend: Indiana is averaging 44.8 PPG (4th nationally) and allowing just 11.3 PPG (4th nationally).

Michigan State Spartans:

Wins: Western Michigan, Boston College, Youngstown State

Losses: USC (45–31), Nebraska (38–27), UCLA (38–13)

Trend: Spartans have lost three straight, allowing 40.3 PPG in Big Ten play.

Injury Report

Michigan State:

QB Aidan Chiles – Questionable (ankle/upper body)

OG Kristian Phillips – Questionable (leg)

TE Michael Masunas – Questionable (undisclosed)

DE Jalen Thompson, DT Ben Roberts, S Nikai Martinez – Game-time decisions

Indiana:

No major injuries reported; QB Fernando Mendoza and RB Roman Hemby expected to start.

Key Player Matchups

QB Fernando Mendoza (Indiana): 1,423 yards, 17 TDs, 2 INTs, 71.2% completion.

RB Roman Hemby (Indiana): 421 yards, 2 TDs – faces MSU defense allowing 264 rushing YPG in Big Ten play.

WR Elijah Sarratt (Indiana): 509 yards, 7 TDs – matchup nightmare for MSU’s depleted secondary.

QB Aidan Chiles (MSU): 1,019 yards, 9 TDs, 3 INTs – questionable, backup Alessio Milivojevic may start.

RB Makhi Frazier (MSU): 383 yards, 2 TDs – must establish run to keep Indiana’s offense off the field.

Series History

Michigan State leads all-time series 51–17–2.

Last meeting (2024): Indiana won 47–10.

Indiana has covered in 9 of last 12 as a home favorite.

Betting Trends:

Indiana is 4-2 ATS in 2025.

Michigan State is 3-3 ATS, but 0-3 in Big Ten play.

Indiana is 9-3 ATS as a home favorite under Curt Cignetti.

Historical Betting Results

Indiana has covered in 3 of last 4 vs. MSU.

The Over has hit in 2 of last 3 meetings.

Average margin of victory in Indiana’s last two wins: +22 points.

Game Odds

Michigan State Spartans               49.5

Indiana Hoosiers                              – 26.5

Odds Courtesy of Sports Odd Direct as of Friday, October 17, 2025

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