Venue & Game Info
Stadium: FirstBank Stadium, 2601 Jess Neely Drive, Nashville, TN 37240
Kickoff: 3:30 PM ET (2:30 PM CT local)
Broadcast: ESPN
Weather Forecast: Sunny, 66°F at kickoff, light winds (5–7 mph), no precipitation expected.
Team Recent Form
Missouri Tigers:
Last game: 23-17 win vs. Auburn
Offense: 39.0 PPG (12th nationally), 487.3 YPG (10th)
Defense: 16.7 PPG allowed (16th), 239.0 YPG allowed (5th)
Strength: Elite rushing attack (244.9 YPG, 7th nationally) and top-5 defense.
Vanderbilt Commodores:
Last game: 31-24 win vs. LSU
Offense: 41.4 PPG (8th), 457.7 YPG (24th)
Defense: 20.0 PPG allowed (33rd), 315.0 YPG allowed (29th)
Strength: Dual-threat QB Diego Pavia and efficient third-down offense (55.7%, 2nd nationally).
Injury Report
Missouri: No major injuries reported.
Vanderbilt: WR Jefferson, DB Hinton, WR Dickey – OUT (undisclosed).
Key Player Matchups
QB Beau Pribula (Mizzou): 1,622 yards, 11 TD, 7 INT, plus 6 rushing TDs.
RB Ahmad Hardy (Mizzou): 840 yards, 11 TD – red-zone workhorse.
WR Kevin Coleman Jr. (Mizzou): 449 yards, 1 TD – explosive playmaker.
QB Diego Pavia (Vandy): 1,569 yards, 15 TD, 4 INT, plus 438 rushing yards and 4 TDs.
RB Sedrick Alexander (Vandy): 364 yards, 6 TD – versatile back.
WR Eli Stowers (Vandy): 355 yards, 2 TD – reliable target.
Series History
Missouri leads the all-time series 10–5.
Missouri has won 4 straight vs. Vanderbilt, including a 38-21 win in 2024.
At Nashville: Missouri has won 3 of last 4.
Betting Trends
Missouri: 5-2 ATS this season; 4 of 7 games OVER.
Vanderbilt: 5-2 ATS; 4 of 7 games OVER.
Head-to-Head: Missouri 4-0 SU last 4 vs. Vanderbilt; 3-1 ATS in that span.
Historical Betting Results: Missouri has covered in 9 of last 13 overall; Vanderbilt 3-1 ATS in last 4 home games.
Projection: Missouri 31 – Vanderbilt 27
Game Odds
Missouri Tigers 53.5
Vanderbilt Commodores – 2.5
Odds Courtesy of Sports Odd Direct as of Friday, October 24, 2025
