FBS-CFB Game Preview:Arizona Wildcats (4-2) vs. Houston Cougars (5-1)

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Venue & Game Details

Location: TDECU Stadium, Houston, TX

Kikoff: 12:00 p.m. ET / 11:00 a.m. CT

Conference: Big 12 matchup

Broadcast: FS1 / Fubo streaming

Weather Forecast: Houston – ~82°F at kickoff, humid, partly cloudy, winds 7–10 mph, ~20% chance of showers

Team Recent Form

Arizona Wildcats:

Last game: Lost 33–27 (2OT) to BYU.

Trend: Averaging 32.2 PPG (50th nationally), allowing 18.5 PPG (27th).

Strength: Top-15 defense in yards allowed (275.7 YPG).

Houston Cougars:

Last game: Beat Oklahoma State 39–17.

Trend: Averaging 29.2 PPG (66th), allowing 17.5 PPG (23rd).

Strength: Top-25 defense (306.5 YPG allowed).

Injury Report

Arizona: No major injuries reported; QB Noah Fifita and RB Ismail Mahdi expected to start.

Houston: RB Stacy Sneed – Probable (ankle); WR Amare Thomas – Healthy, coming off 157-yard game vs. OSU.

 Key Player Matchups

QB Noah Fifita (Arizona): 1,560 yards, 15 TDs, 4 INTs, 62.7% completion.

RB Ismail Mahdi (Arizona): 403 yards, 1 TD – versatile runner.

WR Jayin Whatley (Arizona): 328 yards, 3 TDs – reliable target.

QB Conner Weigman (Houston): 1,216 yards, 8 TDs, 2 INTs, 61.5% completion.

RB Dean Connors (Houston): 438 yards, 4 TDs – physical runner.

WR Amare Thomas (Houston): 441 yards, 2 TDs – deep threat.

Series History

Arizona leads all-time series 1–0.

Last meeting (2024): Arizona won 27–3 in Tucson.

This is the first Big 12 meeting between the programs.

Betting Trends:

Houston is 5-1 ATS this season.

Arizona is 4-2 ATS, but 0-2 ATS as an underdog.

The Under has hit in 3 of Arizona’s 6 games.

Houston is 94.7% red-zone efficiency (18th nationally).

Historical Betting Results

Arizona has covered in 3 of last 5 games.

Houston has covered in 5 of 6 games this season.

Average combined score in last 3 Arizona games: 55.3 points.

Average combined score in last 3 Houston games: 49.0 points.

Game Odds

Arizona Wildcats             – 2.5

Houston Cougars             47.5

Odds Courtesy of Sports Odd Direct as of Friday, October 17, 2025