Venue & Game Info
Stadium: L&N Federal Credit Union Stadium, Louisville, KY
Kickoff: 7:30 PM ET
Broadcast: ACC Network
Weather Forecast: Clear skies, 63°F at kickoff, light winds (5–7 mph), no precipitation expected.
Team Recent Form
Louisville Cardinals:
Last game: 24-21 win vs. Miami (FL)
Offense: 34.0 PPG, 397.8 YPG (282 pass, 116 rush)
Defense: 21.0 PPG allowed, 274 YPG allowed (20th vs. pass, 22nd vs. run)
Strength: Balanced attack, elite defense, +4 turnover margin.
Boston College Eagles:
Last game: 38-23 loss vs. UConn
Offense: 27.1 PPG, 372.6 YPG (272 pass, 100 rush)
Defense: 33.9 PPG allowed, 397.3 YPG allowed (116th vs. pass, 61st vs. run)
Weakness: -5 turnover margin, poor red-zone efficiency.
Injury Report
Louisville: No major injuries reported; WR Chris Bell (probable).
Boston College: Multiple defensive players questionable (DB Amari Jackson, LB Daveon Crouch, DT Owen Stoudmire).
Key Player Matchups
QB Miller Moss (LOU): 1,606 yards, 9 TD, 4 INT, 66.2% completion.
RB Isaac Brown (LOU): 447 yards, 3 TD, 7.5 YPC vs. Miami.
WR Chris Bell (LOU): 638 yards, 6 TD – had 136 yards, 2 TD vs. Miami.
QB Dylan Lonergan (BC): 1,394 yards, 9 TD, 3 INT, 67% completion.
RB Jordan McDonald (BC): 431 yards, 5 TD – 123 yards vs. UConn.
WR Lewis Bond (BC): 505 yards, 0 TD – reliable possession receiver.
Series History
All-time: Boston College leads 7–6.
Recent: Louisville has won 3 of last 4 vs. BC.
Last meeting: Louisville 56, Boston College 28 (2023).
Betting Trends
Louisville: 2-4 ATS this season; 0-2 ATS as 25.5+ point favorite.
Boston College: 2-5 ATS; 0-4 SU as underdog.
Totals: Louisville 3 of 6 OVER; BC 4 of 7 OVER.
Head-to-Head: Louisville 3-1 SU last 4 vs. BC; 3 of last 4 OVER.
Game Odds
Boston College Eagles 54.5
Louisville Cardinals – 25.5
Odds Courtesy of Sports Odd Direct as of Friday, October 24, 2025
