Venue, Date & Time
Location: UB Stadium, Buffalo, New York (Capacity: 29,000)
Kickoff: 3:30 PM ET
Broadcast: ESPN+
Weather Forecast (Buffalo, NY)
Conditions: Partly cloudy, mild
Temperature: ~74°F (23°C) at kickoff
Wind: 5 mph WNW
Impact: Ideal football weather; minimal effect on passing/kicking
Injury Report
Connecticut Huskies
RB Mel Brown – Out (collarbone)
TE Juice Vereen – Questionable
Buffalo Bulls
TE Ryan Daly – Out for season
WR Bobby Mays – Questionable
WR Dwayne Early Jr. – Questionable
RB Terrance Shelton Jr. – Questionable
Key Player Matchups
QB Joe Fagnano (UConn, 1,046 yds, 6 TD, 0 INT) vs. QB Ta’Quan Roberson (Buffalo, 662 yds, 5 TD, 2 INT)
Fagnano has been efficient and turnover-free; Roberson adds mobility (165 rush yds, 2 TD).
RB Cam Edwards (UConn, 500 yds, 5 TD, 6.8 YPC) vs. RB Al-Jay Henderson (Buffalo, 274 yds, 4 TD)
Edwards is the Huskies’ offensive engine; Henderson is Buffalo’s versatile back.
WR Skyler Bell (UConn, 445 yds, 3 TD) vs. WR Victor Snow (Buffalo, 206 yds, 3 TD)
Bell has five straight games with 75+ yds; Snow is Roberson’s top red-zone target.
LB Bryun Parham (UConn, 28 TKL, 5.5 sacks) vs. LB Khalil Murdock (Buffalo, 34 TKL, 2 sacks)
Both linebackers are defensive leaders and disruptors.
Recent Team Forms
UConn Huskies (2-2)
W 31–25 vs. Ball State
L 44–41 OT @ Delaware
L 27–20 OT @ Syracuse
W 59–13 vs. CCSU
Trend: Three of four games decided by one score; offense averaging 37.8 PPG.
Buffalo Bulls (2-2)
L 21–17 vs. Troy
W 31–28 @ Kent State
W 45–6 vs. St. Francis (PA)
L 23–10 @ Minnesota
Trend: Defense solid (19.5 PPG allowed), but offense inconsistent late in games.
Conference Context
UConn: FBS Independent, looking to build bowl eligibility resume.
Buffalo: MAC East member, aiming to rebound after Troy loss.
Cross-Conference Note: A Group of 5 vs. Independent clash with bowl implications.
Series History
All-time H2H: UConn leads 17–5
Current Streak: UConn won last meeting (2024)
Largest Margin: UConn 55–0 (1997)
Trend: UConn has historically dominated, winning 8 straight from 2002–2012.
Betting Trends
UConn:
1–2–1 ATS in 2025
3 of 4 games Over the total
11–1 SU last 12 as favorite
Buffalo:
2–2 ATS in 2025
2 of 4 games Over the total
3–0 ATS last 3 as underdog
Historical Betting Results
2024: UConn -6.5 covered, won 24–14 (Under 47.5)
2019: Buffalo -3 covered, won 31–17 (Under 52.5)
2013: UConn -7 covered, won 41–12 (Over 49.5)
2008: UConn -6.5 covered, won 45–17 (Over 50.5)
Game Odds
Connecticut Huskies – 3.5
Buffalo Bulls 50.5
Odds Courtesy of Sports Odd Direct as of Friday, September 26, 2025
