Kickoff: 3:30 PM ET (2:30 PM CT)
Venue: Vaught-Hemingway Stadium, Oxford, Mississippi
Broadcast: ESPN
Weather Forecast (Oxford, MS)
Temperature: ~84°F (29°C) at kickoff
Conditions: Partly cloudy, humid, light winds (5–8 mph)
Impact: Classic September SEC weather. Heat and humidity could test Tulane’s depth in the second half.
Injury Report
Tulane Green Wave (AAC):
QB Jake Retzlaff (245 yards passing, 111 rushing yards, 4 rushing TDs vs. Duke) healthy and starting.
RB Zuberi Mobley (82 yards, 2 TDs vs. South Alabama) available.
WR Shazz Preston (95 yards vs. Duke) healthy.
No major defensive absences reported, though secondary depth has been tested.
#17 Ole Miss Rebels (SEC):
QB Trinidad Chambliss (353 yards passing, 62 rushing yards, 3 total TDs vs. Arkansas) healthy and leading the offense.
RB Kewan Lacy (44 yards, 1 TD vs. Arkansas) available.
WR Harrison Wallace III (92 yards, 1 TD vs. Arkansas) active.
Defense intact, led by LB Suntarine Perkins.
Key Player Matchups
QB Jake Retzlaff (Tulane) vs. Ole Miss Linebackers
Retzlaff’s dual-threat ability (111 rushing yards, 4 TDs vs. Duke) makes him Tulane’s X-factor.
WR Shazz Preston (Tulane) vs. Ole Miss Secondary
Preston’s big-play ability (31.7 yards per catch vs. Duke) will test the Rebels’ corners.
QB Trinidad Chambliss (Ole Miss) vs. Tulane Pass Rush
Chambliss is efficient and mobile; Tulane must pressure him to avoid a shootout.
RB Kewan Lacy (Ole Miss) vs. Tulane Front Seven
Lacy’s ability to grind out tough yards will be key to controlling tempo.
Recent Team Form
Tulane Green Wave (3–0, AAC)
8/30/25: W 23–3 vs. Northwestern
9/6/25: W 33–31 vs. South Alabama
9/13/25: W 34–27 vs. Duke
Trend: Offense versatile with Retzlaff’s dual-threat play; defense bend-but-don’t-break.
#17 Ole Miss Rebels (3–0, SEC)
8/30/25: W 63–7 vs. Georgia State
9/6/25: W 30–23 @ Kentucky
9/13/25: W 41–35 vs. Arkansas
Trend: Offense explosive (averaging 44.7 PPG), defense vulnerable but opportunistic.
Series History
Ole Miss leads the all-time series 71–15–2.
Last meeting: 2023, Ole Miss defeated Tulane 37–20 in New Orleans.
Tulane has not beaten Ole Miss since 1989.
Betting Trends
Ole Miss:
2–1 ATS in 2025.
Overs hit in all 3 games.
14 straight non-conference home wins; covered in last 7 such games.
Tulane:
2–1 ATS in 2025.
Overs hit in 2 of 3 games.
0–5 SU in last 5 vs. AP-ranked opponents.
Head-to-Head:
Ole Miss has won 13 straight vs. Tulane.
Last Tulane cover came in 2021.
Historical Betting Results
Ole Miss: Reliable ATS at home in non-conference play; strong first-half team (won first half in last 14 non-conference home games).
Tulane: Historically struggles ATS vs. ranked Power Five opponents but has covered 3 of last 4 vs. Top 15 teams in September.
SEC vs. AAC: SEC teams cover ~65% of the time in these matchups.
Game Odds
Tulane Green Wave 61
Mississippi Rebels – 13
Odds Courtesy of Sports Odd Direct as of Friday, September 19, 2025
