MLB Game Preview: Kansas City Royals (73-72) vs. Cleveland Guardians (74-70)

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Cleveland Guardians logo

Venue & Game Details

  • First Pitch: 6:40 PM ET
  • Venue: Progressive Field, 2401 Ontario Street, Cleveland, OH 44115
  • Broadcast: Bally Sports Kansas City, Bally Sports Great Lakes, MLB.TV

Weather Forecast (Cleveland, OH)

  • Kickoff Temp: ~74°F (23°C)
  • Conditions: Partly cloudy, light southwest wind (6–8 mph)
  • Impact: Minimal — ideal baseball weather with no significant wind or rain expected.

Injury Report

Cleveland Guardians:

  • Nic Enright (elbow) — 15-day IL
  • Lane Thomas (foot) — 10-day IL
  • Will Brennan (forearm), Andrew Walters (lat), Ben Lively (forearm), John Means (elbow), Sam Hentges (shoulder) — 60-day IL

Kansas City Royals:

  • Bobby Witt Jr. (back) — Day-to-day
  • Seth Lugo (back), Jonathan India (wrist), Bailey Falter (biceps), Hunter Harvey (abductor), Steven Cruz (shoulder) — 15-day IL
  • Kris Bubic (rotator cuff), Cole Ragans (rotator cuff), Alec Marsh (shoulder), James McArthur (elbow) — 60-day IL

Recent Form (Last 5 Games)

Guardians: W-W-W-W-W — Riding a five-game win streak, outscoring opponents 27–13.
Royals: L-L-L-W-W — Offense cooled, averaging 3.0 runs per game in last five.

Series History

  • 2025 Season Series: Guardians lead 6–4
  • All-Time: Royals lead 740–713
  • Trend: Cleveland has taken 4 of the last 6 meetings this year.

Key Player Matchups

  • Probable Pitchers:
    • KC: Noah Cameron (7–6, 3.03 ERA, 88 K) — Rookie lefty with strong command, 7–4 team record in his last 11 starts.
    • CLE: Joey Cantillo (4–3, 3.73 ERA, 87 K) — Left-hander allowing 1 ER or fewer in 3 of last 4 starts.
  • Impact Bats:
  • KC: Vinnie Pasquantino — 29 HR, .467 SLG; Michael Massey — 11-for-32 last 10 games.
  • CLE: José Ramírez — .283 AVG, 27 HR, 27 2B; Steven Kwan — .349 AVG last 10 games.

Betting Trends

  • Guardians are 7-3 in last 10 games ATS
  • Royals are 2-8 in last 10 road games vs. AL Central
  • Under is 6-2 in Guardians’ last 8 home games
  • Royals are 41-14 when not allowing a home run

Game Odds

Kansas City Royals           8.5

Cleveland Guardians      – 158

Odds Courtesy of Sports Odds Direct as of Tuesday, September 9, 2025