MLB Game Preview: Chicago Cubs (66-48) vs. St. Louis Cardinals (58-58)

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St. Louis Cardinals logo

Game Details

  • Time: 7:15 PM CT / 8:15 PM ET
  • Venue: Busch Stadium, St. Louis, MO
  • Broadcast: MLB Network, Marquee Sports Network
  • Weather: Hot, 90°F, winds blowing out to left field

Team Overview

Chicago Cubs

  • Record: 66–48 (2nd in NL Central)
  • Recent Form: 5–5 in last 10 games
  • Key Players:
    • Kyle Tucker: 21 doubles, 4 triples, 18 HR
    • Nico Hoerner: 13-for-37, 1 HR in last 10 games
    • Ian Happ: 8 hits in last 9 games, 136 career HR vs RHP
  • Pitcher: Matthew Boyd (11–4, 2.34 ERA, 1.03 WHIP, 118 K)

Boyd has been one of the Cubs’ most consistent arms, and Chicago is 28–10 when not allowing a home run.

St. Louis Cardinals

  • Record: 58–58 (4th in NL Central)
  • Recent Form: 4–6 in last 10 games
  • Key Players:
    • Alec Burleson: .279 AVG, 14 HR, 50 RBI
    • Masyn Winn: 11-for-37, 3 doubles, 1 HR in last 10 games
    • Iván Herrera: .869 OPS since returning from IL
  • Pitcher: Michael McGreevy (3–2, 5.08 ERA, 1.23 WHIP, 23 K)

McGreevy has struggled against left-handed hitters, allowing a .301 AVG and ranking in the bottom 15% in strikeout rate.

Head-to-Head Snapshot

Season SeriesResult
2025Cubs lead 4–3
Last MeetingCubs won 6–4

This marks the 8th meeting of the season between these longtime rivals.

Pitching Matchup – August 8

TeamPitcherStats (2025)
CubsMatthew Boyd11–4, 2.34 ERA, 118 K
CardinalsMichael McGreevy3–2, 5.08 ERA, 23 K

Boyd has thrown 130.2 innings this season—his most since 2019—while McGreevy has been vulnerable to lefty bats like Happ and Busch.

Game Odds

Chicago Cubs                     – 156

St. Louis Cardinals           8.5

Odds Courtesy of Sports Odd Direct as of Thursday, August 7, 2025