MLB Game Preview: Cleveland Guardians (37-35) vs. San Francisco Giants (41-33)

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The Cleveland Guardians and San Francisco Giants close out their three-game interleague series on Thursday, June 19, 2025, at Oracle Park in San Francisco. With the Guardians eyeing a sweep and the Giants desperate to snap a four-game skid, this matinee finale is shaping up to be a pivotal clash for two playoff hopefuls.

Game Details

  • Matchup: Cleveland Guardians (37–35) vs. San Francisco Giants (41–33)
  • Date: Thursday, June 19, 2025
  • Time: 4:05 PM ET
  • Venue: Oracle Park, San Francisco, CA
  • Broadcast: NBCS-BA, Bally Sports Great Lakes, MLB.tv

Probable Pitchers

  • Guardians: Gavin Williams (5–3, 3.89 ERA)
  • Giants: Logan Webb (6–5, 2.58 ERA)

Williams has been solid in June, allowing just five earned runs over 16.2 innings across three starts. However, his 12.9% walk rate and elevated xERA suggest some regression may be looming. Webb, meanwhile, has been dominant at home and enters with the 5th-best ERA among qualified starters, backed by MLB’s top-ranked bullpen.

Team Trends

  • Guardians: Have won the first two games of the series despite tallying just 13 total hits. Their defense and timely power—like Daniel Schneemann’s three-run homer—have been the difference.
  • Giants: Have outhit Cleveland 16–13 in the series but are just 1-for-19 with runners in scoring position. They’ve now lost four straight.

Players to Watch

  • José Ramírez (Guardians): Slashing .319/.543/.879 with 13 HR and 29 extra-base hits. His extreme flyball profile matches well against Webb’s groundball tendencies.
  • Steven Kwan (Guardians): Batting .298 with 14 doubles and elite defense. He’s 0-for-6 in the series but made a game-saving throw Tuesday.
  • Rafael Devers (Giants): 15 HR, 59 RBI, and a .505 SLG. He’s 2-for-8 since joining the Giants but remains a key power threat.
  • Heliot Ramos (Giants): Team-best .284 AVG and .465 SLG. Quiet in the series but capable of sparking the offense.
  • Wilmer Flores (Giants): 11 HR and a .459 xSLG vs. righties. He’s struggled lately but has favorable splits against Williams.

Betting Odds & Insights

  • Trend to Know: The Giants are 14–3 when hitting 2+ home runs, but the Guardians are 23–4 when scoring 5+ runs.

Final Thoughts

The Guardians are poised for their first sweep since April, while the Giants are reeling and in need of a spark. With Logan Webb on the mound and Gavin Williams showing signs of vulnerability, expect a tight, low-scoring affair. If San Francisco can finally cash in with runners in scoring position, they may salvage the finale—but Cleveland’s defense and clutch hitting have been the difference so far.

Game Odds

Cleveland Guardians      7

San Francisco Giants      – 181

Odds Courtesy of Sports Odds Direct as of Wednesday, June 18, 2025