Dodger Stadium (UNIQLO Field), Los Angeles, California
First pitch: 10:10 p.m. ET (7:10 p.m. PT)
TV: SportsNet LA / Padres.TV
The Dodgers lead the NL West by a comfortable margin and are rolling with a strong recent stretch. The Padres are firmly in wild-card position and have been hot themselves. This is Game 2 of a three-game series; Los Angeles won the opener 7-0 on Tuesday. The Dodgers lead the season series 8-3 (and are 4-1 at home against San Diego this year).
Probable Pitchers
Padres: LHP Robbie Ray (overall around 13-8, 3.60 ERA across teams; 3-2, 5.22 ERA in limited starts with San Diego after the trade deadline). The veteran lefty has struggled with walks since joining the Padres but brings strikeout ability.
Dodgers: RHP Yoshinobu Yamamoto (14-8, 2.51 ERA, strong WHIP and strikeout numbers). One of the league’s top pitchers this season, he has dominated in September and owns strong career numbers against San Diego (including limited runs allowed in prior 2026 matchups).
Current Weather Forecast
Partly cloudy to clear and warm. Highs in the upper 70s to mid-80s°F earlier in the day, temperatures in the mid-to-upper 70s around first pitch, light southwest winds, low humidity, and near-zero chance of precipitation. Classic late-summer Dodger Stadium conditions.
Injury Reports
Padres:
DH Miguel Andujar (10-day IL, wrist)
1B/OF Gavin Sheets (10-day IL, foot)
RP Jason Adam (shoulder)
RP Jeremiah Estrada (shoulder)
SP Lucas Giolito (60-day IL, elbow)
Longer-term absences including OF Luis Rengifo and others.
Dodgers:
SP Blake Snell (day-to-day, groin)
C Dalton Rushing (10-day IL, elbow)
OF Andy Pages (10-day IL, hand) in some reports
Multiple longer-term IL arms (Roki Sasaki, others)
Shohei Ohtani is expected to return from the IL for this game (as a hitter only).
Key Rosters / Notable Players
Padres: RF Fernando Tatis Jr. (hot recently with power), 3B Manny Machado, CF Jackson Merrill, SS Xander Bogaerts, INF Jake Cronenworth, and a balanced lineup with speed.
Dodgers: DH/OF Shohei Ohtani (returning, 30 HR before IL), 1B Freddie Freeman, SS Mookie Betts, 3B Max Muncy, OF Teoscar Hernández / Kyle Tucker, C Will Smith, and a deep, high-powered offense.
Key Player vs. Player Matchups
Yamamoto’s elite command and stuff will challenge a Padres lineup that relies on Tatis and Machado for production.
Ray (lefty) faces a Dodgers group featuring left-handed threats like Freeman and Ohtani (upon return).
Dodger Stadium’s pitcher-friendly tendencies and the late start favor strong starting pitching.
Recent Team Forms
Padres: Excellent (roughly 8-2 in last 10 before the series opener loss; strong overall late-season surge). Road record around 38-41.
Dodgers: Outstanding (7-3 in last 10, longer winning streaks). Dominant home record (51-28 range) and best record in the NL West.
Series History
12th–13th meetings of 2026 (Dodgers lead 8-3; lead current series 1-0 after the 7-0 shutout). Los Angeles has controlled most of the season series, especially at home.
Betting Trends
Yamamoto’s superiority and the Dodgers’ home dominance create a clear edge, though the high juice on the favorite limits value. Recent series opener stayed under some projections.
Game Odds
San Diego Padres 8
Los Angeles Dodgers – 214
Odds Courtesy of Sports Odds Direct as of Tuesday, September 22, 2026
