MLB Game Preview: Washington Nationals (19-22) vs. Cincinnati Reds (22-19)

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Cincinnati Reds logo

First Pitch: 6:40 p.m. ET / 3:40 p.m. PT

Venue: Great American Ball Park — Cincinnati, Ohio

Surface: Kentucky bluegrass

Capacity: 42,319

Weather Forecast (Cincinnati, OH)

Great American Ball Park is one of MLB’s most hitter‑friendly parks; weather will further influence run environment.

  • Temperature: 70–73°F at first pitch
  • Wind: 10–14 mph blowing out to right-center
  • Humidity: ~62%
  • Rain: 0% — clear, warm spring evening
  • Weather Impact:
    • Significant boost for left-handed power
    • Ball carries extremely well in these conditions
    • Expect a hitter-friendly environment

Injury Report

Washington Nationals

  • CJ Abrams — Healthy
  • Lane Thomas — Day-to-day (ankle soreness)
  • Joey Meneses — Healthy
  • Josiah Gray — OUT (elbow inflammation)
  • Hunter Harvey — Healthy (available in bullpen)

Cincinnati Reds

  • Elly De La Cruz — Healthy
  • Matt McLain — OUT (shoulder surgery)
  • Christian Encarnacion-Strand — OUT (wrist fracture)
  • Nick Lodolo — Healthy (expected to start)
  • Alexis Díaz — Healthy (closer available)

Team Records & Recent Form

Washington Nationals (19–22)

  • Last 10: 4–6
  • Road Record: 8–11
  • Run Differential: -22
  • Recent Form:
    • Offense averaging 4.0 runs over last 10
    • Bullpen inconsistent but improving
    • Rotation thin without Gray

Cincinnati Reds (22–19)

  • Last 10: 6–4
  • Home Record: 12–8
  • Run Differential: +15
  • Recent Form:
    • Offense heating up: 5.2 runs per game over last 10
    • Bullpen strong late with Díaz anchoring
    • Rotation stabilizing with Lodolo back

Probable Starting Pitchers

Washington — RHP Jake Irvin (2–3, 4.12 ERA)

  • WHIP: 1.28
  • K/BB: 34/11
  • Strengths:
    • Good fastball/curveball combo
    • Keeps ball in park when command is sharp
  • Weaknesses:
    • Struggles vs LHB
    • Road ERA significantly higher
  • Matchup Outlook:
    • Reds’ lefties (Friedl, Benson) and switch-hitters (De La Cruz) are dangerous
    • Weather + park dimensions increase HR risk

Cincinnati — LHP Nick Lodolo (3–1, 3.33 ERA)

  • WHIP: 1.14
  • K/BB: 41/9
  • Strengths:
    • Elite strikeout ability
    • Dominant vs LHB
  • Weaknesses:
    • Occasional HR issues vs RH hitters
  • Matchup Outlook:
    • Nationals’ RH bats (Meneses, Ruiz, Thomas if active) match up well
    • Wind blowing out to right slightly helps RH opposite-field power

Key Player Matchups

Elly De La Cruz (CIN) vs. Jake Irvin

  • De La Cruz hitting .298 vs RHP
  • Irvin allows .274 average to switch-hitters
  • Advantage: De La Cruz

CJ Abrams (WSH) vs. Nick Lodolo

  • Abrams hitting .305 vs LHP
  • Lodolo’s curveball is elite vs lefties
  • Advantage: Even

Joey Meneses (WSH) vs. Reds Bullpen

  • Meneses hitting .321 in late innings
  • Reds bullpen has been strong but allows hard contact
  • Advantage: Meneses

TJ Friedl (CIN) vs. Irvin

  • Friedl’s left-handed power plays extremely well in this weather
  • Irvin struggles vs LHB
  • Advantage: Friedl

Series History

  • 2025 Season: Reds won 4 of 6
  • Last 10 Meetings: Reds lead 7–3
  • At Great American Ball Park: Reds 9–4 vs Nationals since 2018
  • Trend: High-scoring games common in Cincinnati

Betting Trends

Washington

  • 3–7 in last 10 road games
  • Over is 6–3 in last 9 Nationals games
  • Nationals 2–6 in last 8 vs NL Central

Cincinnati

  • 5–1 in last 6 home games
  • Over is 7–3 in last 10 Reds games
  • Reds 6–2 in last 8 vs sub-.500 teams

Head-to-Head

  • Over is 5–1 in last 6 meetings
  • Reds have won 7 of last 10 overall

Game Odds

Washington Nationals                   9.5

Cincinnati Reds                                 – 130

Odds Courtesy of Sports Odds Direct as of Monday, May 11, 2026

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