MLB Game Preview: Cincinnati Reds (20-13) vs. Pittsburgh Pirates (18-16)

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Pittsburgh Pirates logo

Venue: PNC Park — Pittsburgh, Pennsylvania

First Pitch: 1:35 PM ET / 10:35 AM PT

Surface: Natural grass

Broadcast: SportsNet Pittsburgh, Bally Sports Ohio, MLB.TV

WEATHER REPORT — PNC PARK

Temperature: 64–67°F at first pitch

Wind: Blowing out to left at 6–10 mph — slight boost for right‑handed pull hitters

Humidity: 52%

Precipitation: <10% chance

Ballpark Impact:

PNC plays neutral‑to‑slightly pitcher‑friendly

Wind out to left increases HR probability by 8–12%

Expect moderate scoring with potential for early offense

INJURY REPORT

Cincinnati Reds

Elly De La Cruz (SS)Probable, minor quad tightness; expected to play

TJ Friedl (OF)Out, wrist fracture

Hunter Greene (SP)Out, shoulder fatigue

Alexis Díaz (CL)Probable, light workload management

Pittsburgh Pirates

Oneil Cruz (SS)Probable, minor ankle soreness

Ke’Bryan Hayes (3B)Questionable, back tightness

David Bednar (CL)Out, forearm strain (10‑day IL)

Marco Gonzales (SP)Out, elbow inflammation

TEAM RECORDS & PERFORMANCE

Cincinnati Reds (20–13)

Run Differential: +27

Road Record: 10–7

Last 10 Games: 6–4

Offense: 4.98 runs/game

Pitching: 4.09 ERA

Bullpen: 3.88 ERA (top‑12 MLB)

Pittsburgh Pirates (18–16)

Run Differential: +6

Home Record: 9–8

Last 10 Games: 5–5

Offense: 4.21 runs/game

Pitching: 4.18 ERA

Bullpen: 4.44 ERA (bottom‑third MLB, worsened without Bednar)

RECENT TEAM FORM

Cincinnati Reds

Offense surging: 5.4 runs/game over last 7

De La Cruz and India driving top‑of‑order production

Rotation inconsistent but bullpen strong late

Excellent situational hitting: .292 AVG w/ RISP last 10 games

Pittsburgh Pirates

Offense streaky: big innings followed by long droughts

Bullpen struggling without Bednar

Starting pitching keeping them competitive

Cruz and Reynolds carrying most of the load

PROBABLE STARTING PITCHERS

Cincinnati — Nick Lodolo (LHP)

2026 Season: 3–1, 3.62 ERA, 1.18 WHIP

Strengths: Strikeouts, vertical movement, tough on lefties

Weaknesses: HR susceptibility when fastball leaks up

Vs. Pirates: 3.95 career ERA

Pittsburgh — Mitch Keller (RHP)

2026 Season: 4–2, 3.44 ERA, 1.16 WHIP

Strengths: Cutter/slider combo, induces weak contact

Weaknesses: Occasional command lapses early in games

Vs. Reds: 4.12 career ERA

KEY PLAYER MATCHUPS

1. Elly De La Cruz (CIN) vs. Mitch Keller (PIT)

De La Cruz crushes elevated fastballs

Keller must keep the ball down and mix cutter/slider Edge: Reds

2. Bryan Reynolds (PIT) vs. Nick Lodolo (CIN)

Reynolds handles left‑handed pitching extremely well

Lodolo’s curveball is the equalizer Edge: Even

3. Spencer Steer (CIN) vs. PNC Park Dimensions

Steer’s gap‑to‑gap power plays well in Pittsburgh

Wind out to left boosts his HR potential Edge: Reds

4. Bullpen Battle

Cincinnati: more reliable late‑inning arms

Pittsburgh: missing Bednar, struggling to close games Edge: Reds

SERIES HISTORY

2025–26 Season Series: Reds lead 3–2 entering this game

Last 10 Meetings: Reds lead 6–4

At PNC Park: Reds have won 5 of last 7

Cincinnati has consistently hit Pittsburgh’s bullpen well.

BETTING TRENDS

Cincinnati Reds

7–3 in last 10 vs. NL Central

Over is 5–2 in last 7 road games

6–1 in last 7 day games

Pittsburgh Pirates

3–6 in last 9 home games

Under is 7–3 in last 10 at PNC

2–5 in last 7 vs. teams above .500

Game Odds

Cincinnati Reds                 7.5

Pittsburgh Pirates            – 120

Odds Courtesy of Sports Odds Direct as of Saturday, May 2, 2026