MLB Game Preview: Los Angeles Dodgers (16-7) vs. San Francisco Giants (10-13)

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Venue, Date & Start Time

Location: Oracle Park, San Francisco, CA

Address: 24 Willie Mays Plaza, San Francisco, CA 94107

First Pitch: 9:45 PM EDT / 6:45 PM PDT

Setting: Chilly Bay Area night — temperatures in the high‑50s, favoring pitchers.

Weather Outlook

Temperature: High‑50s

Impact: Cooler air + marine layer → suppressed carry on fly balls

Handicap: Benefits both starters and two top‑10 bullpens (LAD 3.49 SIERA; SF 3.59).

Injury Report

Los Angeles Dodgers

Notable injuries include:

Mookie Betts (10‑Day IL, back)

Tommy Edman (10‑Day IL, ankle)

Blake Snell (15‑Day IL, shoulder)

Bobby Miller, Evan Phillips, Gavin Stone, Kiké Hernández — all on IL

San Francisco Giants

Key injuries:

Jung Hoo Lee (day‑to‑day, leg)

Harrison Bader (10‑Day IL, hamstring)

Daniel Susac, Jared Oliva, Reiver Sanmartin — IL

Probable Pitching Matchup

Dodgers — RHP Shohei Ohtani (2–0, 0.50 ERA)

WHIP: 0.72

Strikeouts: 18

Notes: Elite run prevention but underlying metrics (94 Location+, .158 BABIP) suggest mild regression ahead.

Giants — RHP Tyler Mahle (0–3, 7.23 ERA)

WHIP: 1.93

Strikeouts: 21

Notes: Poor surface stats, but pitched to a 2.18 ERA last season and historically handles LAD hitters well (6‑for‑29, .207 AVG, 10 K vs Ohtani/Tucker/Muncy).

Pitching Edge: Dodgers on paper, but matchup‑specific data gives Mahle a path to outperform expectations.

Team Records & Recent Form

Los Angeles Dodgers (16–7)

Last 5: L, W, L, L, W

Season: 16–7 overall, 7–4 on the road

13–3 when recording 8+ hits

San Francisco Giants (10–13)

Last 5: W, L, W, W, W (three‑game home win streak)

Season: 10–13 overall, 4–7 at home

Team batting average: .250 (Top‑10 MLB)

Key Player Matchups

Dodgers

Andy Pages: .366 AVG, 5 HR, 21 RBI (red‑hot form)

Freddie Freeman: 12‑for‑37 (.324) last 10 games

Giants

Matt Chapman: .286 AVG, 12 RBI

Jung Hoo Lee: 15‑for‑39 (.385) last 10 games

Series History & Context

Giants won 3–1 in the series opener.

This is the second meeting of the season.

Giants are using this rivalry series as a potential turning point.

Game Odds

Los Angeles Dodgers      – 226

San Francisco Giants      7.5

Odds Courtesy of Sports Odds Direct as of Tuesday, April 21, 2026