TV: NBC (8:20 PM ET): Mike Tirico, Cris Collinsworth, Melissa Stark (field reporter) National Radio: Westwood One (8:20 PM ET): Ryan Radtke, Ross Tucker
All-Time Series History Regular Season: BUF leads series, 7-6 (won past 2)
The Last Time… Regular Season: 12/7/20: BUF 34 at SF 24
HEAD COACHES
Kyle Shanahan vs. Opp. (incl. postseason): 0-1 Reg. Season: 69-57 (.548) Postseason: 8-4 (.667)
Sean McDermott vs. Opp. (incl. postseason): 1-0 Reg. Season: 82-43 (.656) Postseason: 5-6 (.455)
49ERS NOTES
• QB BROCK PURDY has 32 TDs (31 pass, 1 rush) vs. 6 INTs for 113.1 rating in 15 career reg. season road starts. Can become 4th player ever (Tom Brady, Carson Palmer & Russell Wilson) with 100+ rating in 8 straight road starts. • QB BRANDON ALLEN passed for 199 yards & TD vs. INT in 1st start of season in Week 12. HadsTD pass in 8 of his 10 career starts. • RB CHRISTIAN MCCAFFREY had 68 scrimmage yards (37 rec., 31 rush) in Week 12 & has 50+ scrimmage yards in 25 straight games, longest active streak in NFL. Has 15 TDs (10 rush, 5 rec.) in 15 road games with SF. • TE GEORGE KITTLE had 6 catches for 82 yards & 8th rec. TD of season last week, most rec. TD among TEs in 2024. Aims for his 4th in row overall & 5th in row on road with TD catch. Has 509 receptions & 6,916 rec. yards & can become 3rd TE ever (Antonio Gates & Travis Kelce) with 500+ catches & 7,000+ rec. yards in 1st 8 career seasons. • WR DEEBO SAMUEL has 511 rec. yards in 2024, his 5th-career season with 500+ rec. yards. Has 60+ rec. yards in 3 of his 4 road games this season. • WR JAUAN JENNINGS had 5 catches last week & aims for his 4th in row with 5+ catches. Has career highs in catches (47) & rec. yards (628) in 2024. • LB FRED WARNER has 84 tackles in 2024 & is 1 of 6 with 80+ tackles in each of past 7 seasons. Had FR in last meeting. • DL NICK BOSA aims for his 4th in row with sack. • DL LEONARD FLOYD had 2 sacks last week & aims for his 3rd in row with 1.5 sacks. Has 10.5 sacks & 9 TFL in 2023 with Buf. • CB RENARDO GREEN (rookie) aims for his 4th in row with PD. • S MALIK MUSTAPHA (rookie) had 2nd TFL of season last week & aims for his 6th in row with 5+ tackles.
BILLS NOTES
• BILLS can win 7 straight reg. season games in single season for 5th time in franchise history (2022, 1990, 1988, 1964). • QB JOSH ALLEN totaled 317 yards (262 pass, 55 rush) & 2 TDs (1 pass, 1 rush) in Week 11, 39th-career game with both pass & rush TD, 2nd-most all-time. Aims for 3rd in row with 250+ pass yards & 50+ rush yards. Has 2+ TD passes & 95+ rating in 4 of 5 home games this season. Passed for 375 yards & 4 TDs vs. 0 INTs with 139.1 rating in last meeting. Is 6-2 in 8 career starts on SNF. • RB JAMES COOK had 2 rush TDs in Week 11 & is 1 of 4 RBs with 2+ rush TDs in 3+ games this season. Has rush TD in 5 of his past 6. Aims for 5th in row vs. NFC with 100+ scrimmage yards. Has 4 TDs (3 rush, 1 rec.) in his past 3 in primetime. Ranks tied-4th in NFL with 10 rush TDs & is 1st Buf. RB with 10+ rush TDs in season since LeSean McCoy (13 in 2016). • WR KHALIL SHAKIR led team with 8 catches for 70 yards in Week 11. Aims for 6th in row with 6+ catches & 50+ rec. yards. • WR AMARI COOPER had 55 rec. yards in Week 11. Had 108 rec. yards in his last game vs. SF (10/15/23 w/ Cle.). Aims for his 3rd in row on SNF with rec. TD. • WR CURTIS SAMUEL set season highs in catches (5) & rec. yards (58) & had 1st rec. TD of season in Week 11. Aims for 3rd in row with 4+ catches. • LB TERREL BERNARD had 8 tackles & 1st sack & 2nd INT of season in Week 11. Aims for his 5th in row with 8+ tackles & 3rd in row with PD. • LB VON MILLER had 4th sack of season in Week 11. Has 7 TFL & 4 sacks in 4 career games vs. SF. Has 15 sacks in 21 career games on SNF. • LB DORIAN WILLIAMS has 9+ tackles in 2 of past 3. • S TAYLOR RAPP had 6 tackles & INT in Week 11. Aims for 7th in row with 5+ tackles & 3rd in row with INT. Has 7+ tackles in 4 of his past 5 vs. SF.