Venue & Game Details
Kickoff Time: 1:00 PM EDT / 12:00 PM CDT
Venue: NRG Stadium, Houston, Texas
Capacity: ~72,200 (retractable roof)
Broadcast: CBS: Tom McCarthy, Ross Tucker, Tiffany Blackmon & Amanda Balionis (field reporters)
Injury Report
Tennessee Titans:
QB Cam Ward – healthy, but sacked 15 times in 3 games.
RB Tyjae Spears – healthy, leads team in rushing.
WR Treylon Burks – questionable (hamstring).
LT Nicholas Petit-Frere – questionable (ankle).
CB Roger McCreary – questionable (shoulder).
Houston Texans:
QB C.J. Stroud – healthy, but struggling (2 TDs, 3 INTs through 3 games).
WR Christian Kirk – expected to return from groin injury.
OT Laremy Tunsil – questionable (knee).
CB Derek Stingley Jr. – questionable (hamstring).
LB Christian Harris – questionable (shoulder).
Key Player Matchups
Cam Ward (TEN QB) vs. Texans Pass Rush
Ward has been pressured heavily, completing just 54.5% of passes.
Houston’s front seven has 8 sacks but has struggled against mobile QBs.
C.J. Stroud (HOU QB) vs. Titans Secondary
Stroud has 599 yards, 2 TDs, 3 INTs.
Titans’ defense has allowed 94 points in 3 games, ranking bottom-5.
Tyjae Spears (TEN RB) vs. Texans Run Defense
Spears averaging 4.2 ypc.
Texans allowing 118 rushing ypg.
Christian Kirk (HOU WR) vs. Titans CBs
Kirk’s return gives Stroud a reliable target.
Titans’ secondary has allowed 7 passing TDs already.
Recent Team Form
Tennessee Titans (0–3)
L 17–27 vs. Colts (Week 3)
L 20–27 @ Chargers (Week 2)
L 14–28 @ Broncos (Week 1)
Strengths: Young QB flashes, Spears emerging as RB1.
Weaknesses: Offensive line protection, defense allowing 31.3 ppg.
Houston Texans (0–3)
L 15–16 vs. 49ers (Week 3)
L 20–27 @ Commanders (Week 2)
L 17–24 vs. Buccaneers (Week 1)
Strengths: Defensive front, WR depth.
Weaknesses: Offensive line injuries, scoring just 12.7 ppg (last in NFL).
Conference vs. Conference
Both teams are AFC South rivals.
This is a divisional matchup with both teams desperate for their first win.
Early-season divisional games often swing playoff tiebreakers.
Series History
All-time series: Titans lead 23–20.
Last meeting: Texans beat Titans 23–14 in Week 18 of 2024.
Trend: Houston has won 3 of the last 4 meetings.
Betting Trends
Tennessee Titans:
1–2 ATS in 2025.
1–0 ATS as road underdogs this season.
2 of 3 games have gone Over.
Houston Texans:
0–3 ATS in 2025.
0–3 ATS as favorites since 2024.
All 3 games have gone Under.
Historical Betting Results
2024 (Week 18): Texans -2.5 covered in 23–14 win (Under cashed).
2024 (Week 12): Titans +7 covered in 32–27 win (Over cashed).
2023 (Week 15): Texans -3 covered in 19–16 win (Under cashed).
TITANS NOTES
• QB CAM WARD (rookie) completed 23 of 38 atts. (60.5 pct.) for 219 yards & TD last week. Has TD pass in each of past 2 games. • RB TONY POLLARD had 59 scrimmage yards (45 rush, 14 rec.) & rush TD in Week 3. Aims for his 5th in row with 55+ scrimmage yards. Had 129 scrimmage yards (119 rush, 10 rec.) & rush TD in last game at Hou. (11/24/24). • WR ELIC AYOMANOR (rookie) had TD catch last week. Aims for his 3rd in row with TD catch. Is 1 of 3 rookies (Emeka Egbuka & Tory Horton) with TD catch in 2 games this season. • WR CALVIN RIDLEY has 75+ rec. yards in each of his past 3 vs. Hou. Had 3 catches for 76 yards in last meeting. • WR TYLER LOCKETT has 5+ catches & 120+ rec. yards in each of his two career games vs. Hou. Had 5 catches for 142 yards & TD in his last game vs. Hou. (12/12/21 w/ Sea.). • TE CHIG OKONKWO led team with 5 catches & 66 yards in Week 3. Aims for his 3rd in row with 4+ catches. Had 70-yard TD catch in last game at Hou. (11/24/24). Has 55+ scrimmage yards in 3 of his past 4 vs. division. • DT JEFFERY SIMMONS has sack in each of his past 3 at Hou. Had PD in last game at Hou. (11/24/24). • LB CODY BARTON led team with 6 tackles last week. Aims for his 4th in row with 5+ tackles. • S AMANI HOOKER led team with 2 PD & had 5 tackles in Week 3. Has PD in 3 of his past 4. Aims for his 8th in row with 5+ tackles. • S XAVIER WOODS had 5 tackles & PD last week. Has PD in 3 of his past 4. Had 8 tackles & FR in his last game vs. Hou (10/29/23 w/ Car.). Had 5 tackles & 15- yard INT return in his only career game at Hou. (10/7/18 w/ Dal.). • CB JARVIS BROWNLEE had 4 tackles, FR & PD in last meeting. Has 31 tackles (5.2 per game) & 6 PD in 6 games vs. division.
TEXANS NOTES
• QB C.J. STROUD completed 25 of 38 atts. (65.8 pct.) for 204 yards & TD & had 22 rush yards last week. Is 8-4 with 3,052 pass yards (254.3 per game), 20 TDs (19 pass, 1 rush) & 103.9 rating in 12 career starts vs. divison. • RB NICK CHUBB led team with 38 rush yards in Week 3. Had 106 scrimmage yards (80 rush, 26 rec.) & rush TD in his last game vs. Ten. (12/6/20 w/ Cle.). • WR NICO COLLINS led team with 8 catches & 104 rec. yards & had TD catch last week. Has TD catch in 3 of his past 4. Aims for his 3rd in row vs. Ten. with TD catch. • WR CHRISTIAN KIRK has 60+ rec. yards in 3 of his past 4 vs. division. • TE DALTON SCHULTZ had 5 catches in Week 3. Has 5 catches in 2 of his past 3 vs. division. • LB AZEEZ AL-SHAAIR led team with 8 tackles last week. Aims for his 3rd in row with 8+ tackles. Had sack in last home game vs. Ten. (11/24/24). • DE DANIELLE HUNTER has 1.5+ sacks in 3 of his past 4 at home in reg. season. Has 4 sacks in 3 career games vs. Ten. • DE WILL ANDERSON has sack in Week 3. Aims for his 7th in row at home with 0.5+ sack, incl. playoffs. Has 2 sacks in both career games vs. Ten. • LB HENRY TO’OTO’O has TFL in 2 of his past 3. Aims for his 10th in row at home with 5+ tackles, incl. playoffs. • S JALEN PITRE led team with 3 PD & had INT last week. Has PD in 4 of his past 5 vs. division. • CB TREMON SMITH had career-high 4 tackles & 1st-career TFL in Week 3. • CB KAMARI LASSITER had 5 tackles last week. Aims for his 4th in row with 5+ tackles. • CB DEREK STINGLEY had PD in Week 3. Aims for his 3rd in row with PD. Has 2 PD in 2 of his past 3 at home.
Game Odds
Tennessee Titans 38.5
Houston Texans – 7
Odds Courtesy of Sports Odd Direct as of Saturday, September 27, 2025
