NFL Game Preview: New York Jets (3-13) vs. Buffalo Bills (11-5)

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The AFC East rivals close out the 2025 NFL regular season in Week 18, with the Bills locked into a playoff spot and potentially resting starters for health ahead of the postseason, while the Jets, amid a dismal year, seek to end on a high note and improve draft positioning. Buffalo has dominated the division, riding a potent offense led by Josh Allen, against a New York squad plagued by injuries and inefficiencies. This matchup at Highmark Stadium could see lopsided play if the Bills go full throttle, in a rivalry where Buffalo has won recent encounters but New York has historical upset potential.

Venue Location

Highmark Stadium, Orchard Park, New York. This outdoor venue, opened in 1973 with recent renovations, seats approximately 71,608 fans and is known for its passionate “Bills Mafia” crowd and challenging winter conditions.

Kickoff is scheduled for 4:25 p.m. ET (3:25 p.m. CT / 1:25 p.m. PT).

Broadcast: CBS: Andrew Catalon, Charles Davis, Jason McCourty, AJ Ross (field reporter)

Streaming available via Paramount+ or NFL+.

Weather Updates

As an outdoor stadium, weather could significantly impact gameplay, especially passing and special teams. Forecasts indicate cold conditions with highs around 18-25°F, lows near 21°F, winds from the west at 10-20 mph, and a 40% chance of snow showers. Heavy snow is possible, with accumulations of 3-7 cm in some predictions, potentially leading to slippery fields and favoring run-heavy strategies.

Injury Report

Both teams are dealing with extensive injury lists in the finale, with the Bills likely to rest key players given their playoff berth, and the Jets thinned across multiple positions.

New York Jets Injuries:

DE Micheal Clemons: Ankle (DNP).

RB Isaiah Davis: Concussion (DNP).

RB Breece Hall: Knee (DNP).

OL Xavier Newman: Knee (DNP).

CB Qwan’tez Stiggers: Status TBD.

QB Justin Fields: Knee (questionable).

LB Jermaine Johnson: Neck/Calf (questionable).

Others: DB Tony Adams (groin), RB Braelon Allen (IR, knee, out 8-12 weeks); total 10+ players listed, impacting run game and defense.

Buffalo Bills Injuries:

QB Josh Allen: Foot (DNP).

TE Dalton Kincaid: Knee (DNP).

TE Dawson Knox: Knee (DNP).

DB Cam Lewis: Hamstring (DNP).

DT Jordan Phillips: Ankle (DNP).

LB Terrel Bernard: Calf (DNP).

DE Joey Bosa: Hamstring (DNP).

Others: T Dion Dawkins (questionable), DT DaQuan Jones (questionable); 11 players listed, with rest decisions looming.

Player Matchups

Injuries and potential rest for Buffalo add uncertainty, but these battles could define the game’s flow, especially in inclement weather favoring defenses.

Jets RB Breece Hall vs. Bills Rushing Defense: Hall (knee injury) tests Buffalo’s stout front (allowing ~95 rushing YPG), but his status and snow could limit explosiveness.

Bills QB Josh Allen vs. Jets Secondary: Allen (foot) faces a vulnerable New York pass D; if playing limited snaps, expect quick throws, but rest might elevate Mitchell Trubisky.

Jets QB Justin Fields vs. Bills Pass Rush: Fields (knee) exploits Buffalo’s edges if Bosa is out, but weather and Johnson’s status could pressure him.

Giants EDGE Abdul Carter vs. Cowboys O-Line: Wait, wrong; for this: Jets DE Jermaine Johnson vs. Bills OL (e.g., Dawkins questionable), key for containing Buffalo’s run if active.

Recent Team Forms

The Bills have won 4 of their last 5 games, including a 13-12 victory over Philadelphia in Week 17, averaging 27.9 PPG (6th in NFL) with strong home play (6-2).

The Jets have lost 4 of their last 5, falling 42-10 to New England in Week 17, averaging just 18.3 PPG (28th) amid offensive struggles.

Series History

The Bills lead the all-time series 72-58, including a 1-0 postseason edge, dating back to 1960.

footballdb.com +4

Buffalo has won 9 of the last 10 meetings, including a 30-10 victory in Week 2 of 2025.

Betting Trends

Bills: 7-9 ATS overall; 6-2 ATS at home; 3-1 over in last 4.

Jets: 8-8 ATS; 4-1 over in last 5; 1-3 ATS as away underdogs.

Head-to-Head: Bills 9-1 SU in last 10; 4-1 ATS in last 5; overs in 6 of last 10.

JETS NOTES:

• QB BRADY COOK (rookie) passed for 152 yards in Week 17. Aims for his 5th in row with 150+ pass yards. • RB BREECE HALL led team with 129 scrimmage yards (111 rush, 18 rec.) & had rush TD last week. Has 60+ scrimmage yards in 5 of his past 6 on road & has 50+ scrimmage yards in 4 of his 5 career games vs. Buf. • WR JOHN METCHIE had 41 rec. yards last week. • WR ISAIAH WILLIAMS had 35 scrimmage yards (30 rec., 5 rush) in Week 17 Aims for his 4th in row with 4+ catches. • WR ADONAI MITCHELL had 22 rec. yards last week. Aims for his 4th in row on road with 40+ rec. yards. Had 6 catches for 71 yards in his only career game vs. Buf. (11/10/24 w/ Ind.). • LB QUINCY WILLIAMS had 6 tackles in Week 17. Has 6+ tackles in 8 of his past 9. Had 5 tackles & PD in Week 2 meeting. • LB JERMAINE JOHNSON had 2 tackles, TFL & PD last week. Had 4 tackles & PD in Week 2 meeting. • LB JAMIEN SHERWOOD had 7 tackles in Week 17. Aims for his 5th in row with 7+ tackles. Had 13 tackles & 2 TFL in Week 2 meeting. • DT KHALEN SAUNDERS had sack last week. • DT HARRISON PHILLIPS had 5 tackles in Week 17. Aims for his 3rd in row with 5+ tackles. Had 4 tackles in Week 2 meeting. • DT PAYTON PAGE (rookie) had 5 tackles & TFL last week. • DE JOWON BRIGGS had 5 tackles in Week 17. Has sack in 2 of his past 3. Had 5 tackles, sack & FF in Week 2 meeting. • CB BRANDON STEPHENS has 5+ tackles in 3 of his past 4 on road. • CB QWAN’TEZ STIGGERS led team with 10 tackles & had TFL last week. Has PD in 2 of his past 3. • S MALACHI MOORE (rookie) had 7 tackles, TFL & PD in Week 17.

BILLS NOTES:

• BILLS clinched 7th-consecutive playoff berth. • QB JOSH ALLEN completed 23 of 35 atts. (65.7 pct.) for 262 yards & had 2 rush TDs in Week 17. Became youngest in age (29 years, 221 days) & fastest in games (127) to reach 300+ offensive TDs (301). Has 65+ comp. pct., 200+ pass yards & 2+ TDs in each of his 8 home starts this season. • RB JAMES COOK rushed for 74 yards last week. Leads NFL with career-high 1,606 rush yards in 2025. Aims for his 12th in row with 75+ scrimmage yards. Has 2+ TDs in 2 of his past 3. Rushed for 132 yards & 2 TDs in Week 2 meeting. • RB TY JOHNSON had 48 scrimmage yards (33 rec., 15 rush) in Week 17. Aims for his 4th in row at home with 35+ scrimmage yards. • WR BRANDIN COOKS had 4 catches for 101 yards last week. Aims for his 3rd in row vs. NYJ with TD catch. • TE DAWSON KNOX had 5 receptions in Week 17. Aims for his 3rd in row at home with 5+ catches. • DE GREG ROUSSEAU had 3 tackles & half sack last week. Aims for his 4th in row with half sack. Had PD & half sack in Week 2 meeting. • DE JOEY BOSA had 2 tackles & TFL in Week 17. Has PD in 2 of his past 3. Had 2 tackles, 2 FF & sack in Week 2 meeting. • DT DEONE WALKER (rookie) had 3 tackles & TFL last week. • LB MATT MILANO had 7 tackles & half sack in Week 17. Aims for his 4th in row with TFL. Had 5 tackles & TFL in Week 2 meeting. • LB SHAQ THOMPSON had 3 tackles & TFL last week. Has TFL in 3 of his past 4. Had 10 tackles, 2 PD, sack & INT in his last game vs. NYJ (9/12/21 w/ Car.). • CB CHRISTIAN BENFORD had 3 tackles & 2 PD in Week 17. Has PD in 3 of his past 4. Had 4 tackles & TFL in Week 2 meeting. • S COLE BISHOP had 5+ tackles in 3 of his past 4. Aims for his 3rd in row vs. NYJ with 5+ tackles. Had 5 tackles & sack in Week 2 meeting.

Game Odds

New York Jets                    37.5

Buffalo Bills                        – 7.5

Odds Courtesy of Sports Odd Direct as of Saturday, January 3, 2026