Venue & Game Details
Kickoff Time: 1:00 PM EDT
Venue: MetLife Stadium, East Rutherford, New Jersey
Capacity: ~82,500
Broadcast: CBS: Kevin Harlan, Trent Green, Melanie Collins (field reporter)
Weather Forecast (East Rutherford, NJ)
Kickoff Temperature: ~71°F (22°C)
Conditions: Partly cloudy, mild
Wind: 10–13 mph from the west
Precipitation: ~15% chance of light showers
Impact: Comfortable fall weather; no major disruptions expected.
Injury Report
Los Angeles Chargers:
QB Justin Herbert – healthy, 860 yards, 6 TDs, 1 INT through 3 games.
RB Najee Harris – out (ankle); rookie Omarion Hampton expected to start.
WR Keenan Allen – healthy, averaging 80+ ypg.
DE Joey Bosa – questionable (groin).
S Derwin James – healthy, anchors secondary.
New York Giants:
QB Russell Wilson – benched; rookie Jaxson Dart to start.
RB Tyrone Tracy – doubtful (shoulder).
WR Darius Slayton – healthy, leads team in receiving.
OT Joshua Ezeudu – IR (undisclosed).
K Graham Gano – questionable (groin).
Key Player Matchups
Justin Herbert (LAC QB) vs. Giants Secondary
Herbert has been sharp, completing 66% of passes with a 6–1 TD-INT ratio.
Giants’ secondary has allowed 8 passing TDs in 3 games.
Jaxson Dart (NYG QB) vs. Chargers Defense
Rookie making his first NFL start.
Chargers rank top-10 in points allowed and red-zone defense.
Omarion Hampton (LAC RB) vs. Giants Front Seven
Hampton steps into starting role with Harris out.
Giants allowing 128 rushing ypg.
Keenan Allen (LAC WR) vs. Giants CBs
Allen remains Herbert’s go-to target.
Giants’ CB group has struggled in man coverage.
Recent Team Form
Los Angeles Chargers (3–0)
W 27–24 vs. Chiefs (Week 1)
W 31–20 vs. Raiders (Week 2)
W 23–20 vs. Broncos (Week 3, last-second FG)
Strengths: Balanced offense, top-10 defense.
Weaknesses: Run game inconsistent without Harris.
New York Giants (0–3)
L 17–34 vs. Cowboys (Week 1)
L 20–27 vs. Commanders (Week 2)
L 13–31 vs. Chiefs (Week 3)
Strengths: Defensive line flashes.
Weaknesses: QB instability, offense averaging just 16.7 ppg.
Conference vs. Conference
Chargers: AFC West
Giants: NFC East
Cross-conference matchup; rare meeting with no direct playoff tiebreaker impact, but momentum is critical for both.
Series History
All-time series: Giants lead 7–6.
Last meeting: Chargers won 37–21 in Los Angeles (Dec. 12, 2021).
Trend: Chargers have won 2 straight.
Betting Trends
Los Angeles Chargers:
3–0 ATS in 2025.
5–1 ATS in last 6 road games.
2 of 3 games have gone Under.
New York Giants:
0–3 ATS in 2025.
1–6 ATS in last 7 home games.
2 of 3 games have gone Over.
Historical Betting Results
2021: Chargers -9.5 covered in 37–21 win (Over cashed).
2017: Chargers -3 covered in 27–22 win (Over cashed).
2013: Chargers -3 covered in 37–14 win (Over cashed).
CHARGERS NOTES
• CHARGERS are 3-0 for 1st time since 2002, when they began season 4-0. • QB JUSTIN HERBERT passed for 300 yards & TD last week. Is only player in NFL with 300+ pass yards in 2 games this season. Has 2+ TD passes & 120+ rating in 2 of 3 games this season. Can become 1st player in NFL history with 0 INTs in 10 straight road games, min. 15 atts. in each game. Aims for 5th in row on road with 100+ rating. Passed for 275 yards & 3 TDs vs. 0 INTs with 133.1 rating in last meeting. Leads NFL with 860 pass yards in 2025. • RB OMARION HAMPTON led team with season-high 129 scrimmage yards (70 rush, 59 rec.) with 6 catches & 1st-career rush TD last week, most yards by any rookie in a game this season. Ranks 2nd among rookies with 215 scrimmage yards (142 rush, 73 rec.) in 2025. • WR KEENAN ALLEN aims for 4th in row with 5+ catches, 60+ rec. yards & rec. TD. Is 1 of 2 in NFL (Rome Odunze) with TD catch in each of 1st 3 weeks of season. Has 55+ rec. yards in each of 2 career games vs. NYG. • WR QUENTIN JOHNSTON had season highs in catches (6) & rec. yards (89) last week. Is 1 of 3 in NFL with 70+ rec. yards in each of 1st 3 weeks of season. Has TD catch in 2 of 3 games this season. • WR LADD MCCONKEY aims for his 11th in row with 4+ catches. • LB DAIYAN HENLEY has sack in 2 of 3 games this season. • LB TROY DYE had 1st sack of season in Week 3. • DT DA’SHAWN HAND had 1st PD of season last week. • CB TARHEEB STILL aims for his 3rd in row on road with 7+ tackles & TFL. • CB BENJAMIN ST-JUSTE had 1st PD of season in Week 3. • S DERWIN JAMES led team with season-high 12 tackles & career-high 4 TFL & had 1st sack of season last week. Aims for 4th in row with 7+ tackles. Has TFL in 4 of his past 5. • S TONY JEFFERSON has PD in each of his 2 games this season.
GIANTS NOTES
• QB RUSSELL WILSON has 10 TDs vs. 3 INTs for 99.2 rating in 5 career starts vs. Chargers, incl. 2+ TD passes in 4 of 5 starts. Has 353 career reg. season TD passes, 12th-most in NFL history. • QB JAXSON DART (rookie) can make 1st career start. • RB CAM SKATTEBO (rookie) had 6 receptions, career-high 121 scrimmage yards (61 rec., 60 rush) & rush TD in Week 3. Aims for his 3rd in row with 50+ scrimmage yards & rush TD. • RB DEVIN SINGLETARY had 102 scrimmage yards (82 rush, 20 rec.) in his only career game vs. LAC (11/29/20 w/ Buf.). • WR MALIK NABERS has 5+ catches & 50+ rec. yards in 16 of his 18 career games, incl. 5 of his past 6 at home. Has 125 catches in 18 career games & can surpass Brock Bowers (126) for 2nd-most by player in 1st 20 career games all-time. • WR WAN’DALE ROBINSON has 5+ catches in 5 of his past 6. • LB BRIAN BURNS had sack, FF & 2 PD last week in his 100th career game, his 11th-career FF. Aims for his 4th in row with sack. Had sack & FF in his only career game vs. LAC (9/27/20 w/ Car.). • LB KAYVON THIBODEAUX has TFL in 4 of his past 5. • LB ADBUL CARTER (rookie) had 1st-career TFL last week. • LB BOBBY OKEREKE leads NFL with 34 tackles in 2025. Aims for his 15th in row with 5+ tackles. • DT DEXTER LAWRENCE had 7 tackles & sack in last meeting. • CB PAULSON ADEBO aims for his 4th in row with 7+ tackles & PD. • CB DRU PHILLIPS aims for his 3rd in row with TFL & 2+ PD. • S JEVON HOLLAND had career-high 14 tackles in his last game vs. LAC (9/10/23 w/ Mia.). • S TYLER NUBIN aims for his 3rd in row with TFL.
Game Odds
Los Angeles Chargers – 6
New York Giants 43.5
Odds Courtesy of Sports Odd Direct as of Saturday, September 27, 2025
