Venue & Game Details
Location: Mercedes-Benz Stadium, 441 Martin Luther King Jr. Drive NW, Atlanta, GA 30313
Kickoff: 7:15 p.m. ET / 4:15 p.m. PT
Broadcast: ESPN: Chris Fowler, Louis Riddick, Dan Orlovsky, Katie George (field reporter), Peter Schrager (field reporter)
Westwood One: Kevin Kugler, Derek Rackley
Weather Forecast
Conditions: Game is indoors under the retractable roof → no weather impact.
Outside Atlanta: ~73°F, clear skies, light 7 mph NE winds
Injury Report
Buffalo Bills
LB Matt Milano (pectoral) – Out (re-aggravated injury)
DT Ed Oliver (ankle) – Questionable, trending toward return
LB Dorian Williams (knee) – Questionable
DT T.J. Sanders (knee) – Questionable
OT Dion Dawkins (thumb) – Limited, expected to play
K Tyler Bass (hip) – IR
CB Maxwell Hairston, S Wande Owens, DT DeWayne Carter – IR
Atlanta Falcons
WR Darnell Mooney (hamstring) – Questionable
CB A.J. Terrell (hamstring) – Expected to return
CB Clark Phillips III (triceps) – Questionable
CB Natrone Brooks (concussion/shoulder) – Questionable
WR KhaDarel Hodge (groin) – Questionable
RB Nathan Carter (hamstring) – Full participant, expected to play
DT Ta’Quon Graham (calf) – Designated to return from IR
Player Matchups
Josh Allen (BUF QB) vs. Falcons Secondary: Allen has 964 yards, 7 TDs, 3 INTs. Atlanta ranks #1 in total defense and #1 in pass defense (135 YPG allowed).
James Cook (BUF RB) vs. Falcons Run Defense: Cook has 401 yards, 5 TDs. Falcons allow 109 rush YPG (14th).
Dalton Kincaid (BUF TE) vs. Falcons Safeties: Kincaid leads Buffalo with 287 yards, 3 TDs.
Michael Penix Jr. (ATL QB) vs. Bills Pass Rush: Penix has 918 yards, 3 TDs. Bills allow just 125 pass YPG (best in NFL).
Bijan Robinson (ATL RB) vs. Bills Run Defense: Robinson has 314 rush yards, 270 receiving yards. Bills allow 164 rush YPG (31st).
Team Records & Recent Form
Buffalo Bills (4-1)
Last 5: L vs NE (23-20), W vs NO (31-19), W @ NYJ (30-10), W @ TB (23-19), W vs BAL (41-40)
Strengths: #1 rushing offense (163 YPG), #2 scoring offense (33.3 PPG)
Weakness: Run defense (31st, 164 YPG allowed)
Atlanta Falcons (2-2)
Last 5: W vs WSH (34-27), L @ CAR (30-0), L vs TB (23-20), W @ MIN (22-6)
Strengths: #1 total defense (244 YPG allowed), #1 pass defense (135 YPG allowed)
Weakness: Inconsistent QB play, scoring just 19 PPG (25th)
Series History
All-time: Falcons lead 7-6
Last meeting: Bills 29, Falcons 15 (Jan 2, 2022, in Buffalo)
Betting Trends
Bills: 2-3 ATS, 5-2 O/U in last 7 games
Falcons: 2-2 ATS, Under is 9-4 in last 13 games
Bills are 6-1 SU in last 7 vs NFC opponents
Falcons are 3-8-1 ATS in last 12 overall
BILLS NOTES:
• QB JOSH ALLEN completed 22 of 31 atts. (71 pct.) for 253 yards & 2 TDs vs. INT with 103.3 rating & had 53 rush yards last week. Is 5th QB ever with 70+ comp. pct. & 2+ TD passes in 4 of team’s 1st 5 games of season. Aims for his 5th in row on road with 0 INTs. Rushed for 81 yards & 2 TDs in last meeting. Aims for his 6th in row in primetime with 70+ comp. pct., 2+ TD passes & 100+ rating. • RB JAMES COOK has rush TD in 8 of his past 9 & 100+ scrimmage yards in 4 of past 5. Has 100+ scrimmage yards in 7 of his past 8 vs. NFC. Ranks 2nd in NFL with 450 rush yards & tied-2nd with 5 rush TDs this season. • WR KHALIL SHAKIR had 6 catches for 45 yards last week. Aims for 3rd in row with 5+ catches. Has rec. TD in 2 of past 3 on road. • WR KEON COLEMAN had 2nd TD catch of season in Week 5. Has rec. TD in 2 of 3 primetime games this season. • WR CURTIS SAMUEL had 1st TD catch of season last week. Had rec. TD in his last game vs. Atl. (10/15/23 w/ Was.). • TE DALTON KINCAID led team with season highs in catches (6) & rec. yards (career-high 108) last week. Has TD catch in 2 of past 3. • DE JOEY BOSA leads NFL with 4 FFs this season. Has 6 sacks & 2 FFs in 7 career games on MNF. • DE GREG ROUSSEAU had season-high 6 tackles & 2 TFL with 1st full sack of season last week. Aims for his 3rd in row on road with 0.5+ sacks. Had sack & FF in last meeting. Has TFL in 5 of his past 6 on MNF. • LB TERREL BERNARD had 6 tackles TFL & 2nd FR of season in Week 5. Aims for 4th in row with 6+ tackles. Has TFL in 2 of past 3. • LB SHAQ THOMPSON had 5 tackles & 1st sack & FF of season last week. Has 5+ tackles & TFL in 2 of past 3. Has 0.5+ sacks in 3 of his past 4 vs. Atl. • CB TRE’DAVIOUS WHITE has TFL in each of his 4 games this season. • S COLE BISHOP had 2nd sack of season last week. Has 5 tackles in 3 of past 4.
FALCONS NOTES:
• QB MICHAEL PENIX set career highs as starter in comp. pct. (76.9), pass yards (313) & rating (126) with 2 TD passes in Week 4. Has 300+ pass yards & 2 TD passes in 2 of past 3 at home. • RB BIJAN ROBINSON led team with career-high 181 scrimmage (career-high 106 rec., 75 rush) & had rush TD in Week 4. Is 1 of 2 (Christian McCaffrey) with 110+ scrimmage yards in 4 games this season & is 5th RB in SB era with 100+ rec. yards in 2 of his team’s 1st 4 games of season. Aims for his 11th in row overall with 95+ scrimmage yards & 8th in row at home with 100+ scrimmage yards. Has 120+ scrimmage yards in each of 2 career games on MNF & has 652 scrimmage yards (108.7 per game) in 6 career games in primetime. • RB TYLER ALLGEIER rushed for 51 yards & TD in Week 4 & has 50+ rush yards & rush TD in 2 of past 3. • WR DRAKE LONDON led team with season-high 110 yards & 1st TD of season in Week 4. Has 5+ catches & 55+ rec. yards in 6 of his past 7. Has 110+ rec. yards & TD catch in 2 of his past 3 at home. Has TD catch in 5 of 7 career games in primetime, incl. both on MNF. • TE KYLE PITTS had 5 catches for season-high 70 yards & 1st TD of season in Week 4. Aims for 5th in row with 4+ catches. Had 69 rec. yards in last meeting. • LB KADEN ELLIS aims for 3rd in row with 5+ tackles & 0.5+ sacks. Had sack in only career game vs. Buf. (11/25/21 w/ NO). • ED LEONARD FLOYD had season-high 4 tackles & half sack in Week 4. Has 0.5+ sacks in 2 of past 3. Totaled 10.5 sacks with Buf. in 2023. • DL ZACH HARRISON had sack in Week 4 & has sack in 2 of past 3. • S JESSIE BATES led team with 7 tackles in Week 4 & has 7 tackles in 3 of 4 games this season. Had 8 tackles in his last game vs. Buf. (9/22/19 w/ Cin.). • S XAVIER WATTS had 5 tackles & INT in Week 4 & is only rookie with 2+ INTs this season. Has 5+ tackles in 3 of 4 games.
Game Odds
Buffalo Bills – 4.5
Atlanta Falcons 49.5
Odds Courtesy of Sports Odd Direct as of Sunday, October 12, 2025
