NFL Game Preview: Arizona Cardinals (3-8) vs. Tampa Bay Buccaneers (6-5)

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Venue & Game Details

Location: Raymond James Stadium, Tampa, FL

Date & Time: Thursday, November 27, 2025, 1:00 PM ET

Broadcast: FOX: Kevin Kugler, Daryl Johnston, Allison Williams (field reporter)

Weather Forecast

High/Low: 78°F / 66°F

Conditions: Partly cloudy, humid

Winds: 10 mph from the southeast

Precipitation: 15% chance of showers — warm Florida conditions, minimal weather impact

Injury Report

Arizona Cardinals:

QB Kyler Murray (hamstring) – Questionable

WR Michael Wilson (ankle) – OUT

RB James Conner (shoulder) – Questionable

CB Garrett Williams (concussion) – OUT

LT Paris Johnson Jr. (knee) – Questionable

Tampa Bay Buccaneers:

QB Baker Mayfield (shoulder) – Questionable

WR Mike Evans (groin) – Questionable

RB Rachaad White (ankle) – Questionable

CB Carlton Davis (hamstring) – OUT

LB Lavonte David (foot) – Questionable

Team Recent Form

Arizona Cardinals: Lost 4 of last 5; offense averaging 18.1 points per game.

Tampa Bay Buccaneers: Won 3 of last 4; defense allowing 20.7 points per game.

Player Matchups

QB Battle: Kyler Murray (if active) vs Baker Mayfield. Both mobile QBs, but Mayfield has been steadier in 2025.

WRs: Marquise “Hollywood” Brown vs Mike Evans. Evans is nursing a groin injury but remains Tampa’s top red-zone threat.

RBs: James Conner vs Rachaad White. Both questionable, but White has been more consistent in recent weeks.

Defense: Cardinals’ Budda Baker vs Buccaneers’ Antoine Winfield Jr. — two elite safeties anchoring their units.

Series History

All-time: Buccaneers lead 12–11

Recent: Cardinals won last meeting 27–23 (Nov 2022)

Trend: Buccaneers have won 3 of last 5 in Tampa

Betting Trends

ATS Records: Cardinals 4–7 ATS; Buccaneers 7–4 ATS

Totals: Cardinals UNDER 7–4; Buccaneers OVER 6–5

Home/Away Trends: Buccaneers 4–2 at home; Cardinals 1–4 on road

Bottom Line

This game features two teams trending in opposite directions. The Buccaneers are fighting for playoff positioning, while the Cardinals are in rebuilding mode. Tampa Bay’s defense and home-field edge make them favorites, but Kyler Murray’s potential return adds volatility. Expect a physical, lower-scoring contest with Tampa Bay likely to grind out a win.

CARDINALS NOTES:

• QB JACOBY BRISSETT passed for 317 yards & TD in Week 12. Has 250+ pass yards & TD in all 6 starts this season. Ranks 1st in NFL with 175 comp. & 1,985 pass yards since Week 6. Passed for 210 yards & TD in last game vs. TB (11/27/22 w/ Cle.). Aims for 4th in row on road with 2+ TD passes. • RB BAM KNIGHT had rush TD in Week 12 & aims for 3rd in row with rush TD. Has 40+ scrimmage yards in 2 of his past 3 on road. • WR GREG DORTCH had TD catch last week & aims for 4th in row with scrimmage TD. Has scrimmage TD in 2 of his past 3 road games. • WR MICHAEL WILSON led team with 10 catches for 118 yards last week & aims for 3rd in row with 100+ rec. yards. Has 40+ rec. yards in 5 of his past 6 games. • TE TREY MCBRIDE had 9 receptions for 79 yards in Week 12. Has 301 receptions since entering the NFL in 2021, tied with Jimmy Graham for most catches by TE in his 1st 4 seasons in NFL history. Leads TEs with 80 receptions & 797 rec. yards & ranks tied-1st with 7 TDs in 2025. • LB JOSH SWEAT has sack in 3 of his past 4 & ranks tied-7th with 9 sacks this season. Had sack in last game vs. TB (09/29/24, w/ Phi.). • LB JORDAN BURCH had 1st sack of season & PD last week. • LB AKEEM DAVIS-GAITHER had 1st INT of season in Week 12. • DL CALAIS CAMPBELL had half sack & PD last week. Ranks 4th in NFL with 116 sacks since entering the league in 2008. • DL WALTER NOLEN had FR-TD in Week 12, the only rookie to do so in 2025. • CB GARRETT WILLIAMS had 1st INT of season last week. • S JALEN THOMPSON tied for team-high 9 tackles & had sack, PD & FF in Week 12. Aims for 3rd in row with PD & 8th in row on road with 5+ tackles. Had 10 tackles & PD in last meeting. • S BUDDA BAKER co-led team with 9 tackles & had 10th career sack, INT & PD last week. Has 5+ tackles in all 11 games this season. Had 9 tackles & PD in last meeting

BUCCANEERS NOTES:

• QB BAKER MAYFIELD has TD pass in 10 of 11 games this season. Ranks 5th in NFC with 18 TD passes in 2025. • QB TEDDY BRIDGEWATER has 15,182 pass yards & 75 TD passes in 83 career games (65 starts) since entering the NFL in 2014. Had 276 pass yards & 2 TDs in last game vs. Phi. (10/4/20 w/ Car.) • RB SEAN TUCKER led team with 42 rush yards in Week 12. Has 50+ scrimmage yards in 2 of his past 3 games. • RB RACHAAD WHITE aims for 3rd in row at home with 50+ scrimmage yards. Aims for 2,500 career rush yards (2,498) & 15th career rush TD (14). • RB BUCKY IRVING had 165 scrimmage yards (102 rec., 63 rush) & rec. TD in last game (Week 4). • WR EMEKA EGBUKA ranks 1st among rookies in TD catches (6) & 2nd in rec. yards (749) this season. Has 100+ rec. yards & TD in 2 of his past 3 games at home. Aims for 6th in row with 3+ receptions. • WR STERLING SHEPHERD aims for 25th in row with reception. • TE TEZ JOHNSON had 5th TD catch in 2025 last week, tied for 2nd-most among rookies this season. Aims for 3rd in row at home with TD reception. • LB LAVONTE DAVID co-led team with 8 tackles & TFL in Week 12. Has 6+ tackles in 6 of his past 7. Has TFL in 3 of his past 4 at home. Has 176 TFL since entering the NFL in 2012, tied for 2nd-most during that span. Had 10 tackles & TFL in last meeting. • LB YAYA DIABY had 5th sack of season in Week 12. • LB SIRVOCEA DENNIS had 7 tackles last week. Has PD in 2 of his past 3. • CB ZYON MCCOLLUM has PD in 3 of his past 4. • S ANTOINE WINFIELD JR. tied for team-high 8 tackles last week. Has 6+ tackles in 3 of his past 4 & PD in 3 of his past 4. • S TYKEE SMITH aims for 5th in row with PD. Has 5+ tackles in all 11 games this season

Game Odds

Arizona Cardinals                            44.5

Tampa Bay Buccaneers                  – 3.5

Odds Courtesy of Sports Odd Direct as of Saturday, November 29, 2025