First Pitch is scheduled for 10:10 PM ET
Venue: Dodger Stadium (UNIQLO Field at Dodger Stadium), Los Angeles, California
TV: SportsNet LA, MLB.TV | Radio: Guardians Radio Network (WTAM 1100 / 92.3 FM), AM 570 / KTNQ 1020 AM (LAD)

Game Overview

This early-season interleague series opener pits the visiting Cleveland Guardians (2-2, 2nd in AL Central) against the host Los Angeles Dodgers (3-0, 1st in NL West). The Guardians split a four-game set with the Mariners to open the year, showing resilience in extra-inning play but still searching for offensive consistency. The Dodgers opened with a dominant three-game sweep of the Diamondbacks and now host the first three games of the 2026 series at Dodger Stadium, leveraging home-field momentum and one of the league’s most talented (albeit injury-depleted) lineups.

Recent Team Forms

Guardians (2-2): Cleveland went 2-2 in their season-opening road series against Seattle, including an extra-inning win and a shutout loss. Offense has been solid but streaky; the bullpen has held up well despite early tests. They enter this road series with a balanced but unproven attack.

Dodgers (3-0): Los Angeles has looked elite out of the gate, posting strong run production and pitching depth in limited action while sweeping Arizona. They’re 3-0 straight up and riding high at home to begin the year.

Probable Pitchers & Player Matchups

Guardians: LHP Parker Messick (0-0, strong spring: 2.72 ERA) vs. Dodgers: RHP Roki Sasaki (0-0, 2026 MLB debut)

Messick, the young left-hander, impressed in spring with command, a solid fastball-slider-changeup mix, and ground-ball tendencies (limited innings in 2025 rookie action but elite 3.06 xERA). He’ll face a star-studded Dodgers lineup featuring Mookie Betts (SS/RF), Shohei Ohtani (DH), Freddie Freeman (1B), Will Smith (C), and emerging threats like Miguel Rojas or Teoscar Hernández.

Sasaki, the highly touted Japanese right-hander making his season debut, brings elite velocity, a devastating splitter, and strikeout stuff (rocked in limited spring action but with ace upside). He’ll square off against the Guardians’ core, including José Ramírez (3B, .321 AVG / .897 OPS in 13 career games vs. LAD), Steven Kwan (LF), and power/speed from Chase DeLauter (RF) and others.

Key matchup edges: Messick’s command and lefty profile versus Los Angeles’ patient, power-heavy approach; Sasaki’s swing-and-miss arsenal versus Cleveland’s contact-oriented, high-OBP lineup. Dodger Stadium’s pitcher-friendly dimensions should favor a low-scoring, high-strikeout affair.

Injury Report

Guardians

Hunter Gaddis (RP): 15-Day IL (right forearm strain) – out until early April.

George Valera (OF): 10-Day IL (left calf strain) – out until early April.

Tanner Bibee (SP): Day-to-day (right shoulder inflammation) – played catch recently but status uncertain for next turn.
Cleveland’s bullpen and outfield depth are thinned early, forcing reliance on call-ups.

Dodgers

Tommy Edman (IF/OF): 10-Day IL (right ankle surgery) – out until late May.

Blake Snell (SP): 15-Day IL (left shoulder fatigue) – out until late May.

Gavin Stone (SP): 15-Day IL (right shoulder inflammation).

Brusdar Graterol (RP): 15-Day IL (right shoulder/labrum surgery).

Brock Stewart (RP): 15-Day IL (right shoulder surgery).

Landon Knack (SP): 15-Day IL (intercostal strain).

Bobby Miller (SP): 60-Day IL (right shoulder soreness).

Kiké Hernández (INF/OF): 60-Day IL (left elbow surgery).

Longer-term: Evan Phillips (RP, Tommy John – midseason).
Los Angeles is significantly thin in the rotation and high-leverage bullpen but has promoted depth arms to cover.

Series History

The clubs have been competitive in recent interleague play, with tight games often decided late. José Ramírez has historically feasted on Dodgers pitching (.321 AVG, .897 OPS in 13 career games). This marks the 2026 opener of the three-game set, with the Dodgers hosting all three at Dodger Stadium.

Weather Updates

Game-time conditions at Dodger Stadium: ~65–70°F (cooling from daytime highs near 78°F), pleasant with times of clouds and sun, light winds ~5–8 mph, humidity ~50–60%, precipitation chance near 0%. Ideal early-season evening baseball weather—comfortable temperatures with neutral park effects and no rain or wind concerns expected.

Game Odds

Cleveland Guardians      9

Los Angeles Dodgers      – 194

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 0:10 PM ET
Venue: Chase Field, Phoenix, Arizona
TV: D-backs.TV, Detroit SportsNet (DSN), MLB.TV | Radio: 97.1 The Ticket (DET), Arizona Sports 98.7 FM / 620 AM (ARI)

Game Overview

This interleague series opener highlights a sharp contrast in early momentum: the visiting Detroit Tigers (2-1, 1st in AL Central) carry a strong start into Chase Field, while the host Arizona Diamondbacks (0-3, 3rd in NL West) open their 2026 home schedule winless after a tough road trip against the Dodgers. The Tigers have shown balance early, while Arizona is searching for its first victory amid pitching depth concerns and a thin lineup. This marks the first 2026 meeting between the clubs, with the Diamondbacks hosting the three-game set.

Recent Team Forms

Tigers (2-1): Detroit has looked sharp out of the gate with solid run production, timely hitting, and a competitive bullpen. They’re 2-1 straight up (including road success) and enter with positive momentum after a balanced opening stretch.

Diamondbacks (0-3): Arizona has struggled early, posting low scoring output and allowing runs at a concerning clip while going 0-3 SU. The bullpen has been tested, and they’re 0-3 at home to begin the year as they try to halt a three-game skid.

Probable Pitchers & Player Matchups

Tigers: RHP Justin Verlander (0-0, veteran ace profile) vs. Diamondbacks: RHP Michael Soroka (0-0, ~4.52 ERA career recent form)

Verlander, returning to the Tigers for his first start with the club since 2017, brings elite command, a fastball-cutter-curve mix, and proven big-game experience at age 43. He’ll face a Diamondbacks lineup missing key pieces but still featuring Ketel Marte (2B), Corbin Carroll (CF), and power threats like Eugenio Suárez and Josh Bell.

Soroka, making his D-backs home-opener start after signing in the offseason, relies on sinker-slider-changeup to induce ground balls but has shown command issues in recent limited action. He’ll square off against the Tigers’ young core, including Riley Greene (OF), Colt Keith (2B/INF), and veterans like Javier Báez and Mark Canha.

Key matchup edges: Verlander’s veteran pedigree and strike-throwing versus Soroka’s contact management against Detroit’s patient, high-contact approach; Soroka’s ground-ball tendencies versus Chase Field’s neutral dimensions. Expect a competitive, potentially low-scoring affair with Verlander’s experience giving Detroit the early edge.

Injury Report

Tigers

Beau Brieske (RP): 60-Day IL (left adductor/groin strain) – out until late May.

Reese Olson (SP): 60-Day IL (right shoulder labrum surgery) – out until mid-May.

Sawyer Gipson-Long (SP): 15-Day IL (left oblique strain) – out until early April.

Bailey Horn (LHP/RP): 15-Day IL (left elbow arthroscopy) – out until mid-April.

Trey Sweeney (SS): 10-Day IL (right shoulder strain) – out until early April.

Jackson Jobe (SP): 60-Day IL (Tommy John recovery) – out until late May.
Detroit’s rotation and bullpen depth are tested early, but the lineup remains largely intact with recent positive updates on position players like Riley Greene.

Diamondbacks

Lourdes Gurriel Jr. (OF): 10-Day IL (right knee/ACL recovery) – out until early May.

Adrian Del Castillo (C): 10-Day IL (left calf strain) – out until early April.

Tyler Locklear (1B): 10-Day IL (elbow/shoulder surgeries) – out until mid-May.

Merrill Kelly (SP): 15-Day IL (back issue) – out until mid-April.

A.J. Puk (RP): 60-Day IL (elbow surgery) – out until mid-season.

Blake Walston (SP): 60-Day IL (elbow/Tommy John) – out until July.

Corbin Burnes (SP): 60-Day IL (UCL/Tommy John) – out until July.

Cristian Mena (SP): 60-Day IL (right shoulder strain) – out until late May.
Arizona’s rotation and outfield/catching depth are significantly thinned, forcing heavy reliance on call-ups and bullpen usage.

Series History

The clubs have been competitive in recent interleague play, with no dominant trend but tight games often decided by pitching. This marks the 2026 opener of the three-game set at Chase Field, where Arizona has historically performed solidly in home openers against AL clubs.

Game Odds

Detroit Tigers                    9

Arizona Diamondbacks – 118

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 9:40 PM ET
Venue: T-Mobile Park, Seattle, Washington
TV: YES Network, MLB.TV, Root Sports NW | Radio: WFAN 660 AM / 101.9 FM (NYY), Seattle Sports 710 AM (SEA)

Game Overview

This early-season interleague series opener sends the red-hot visiting New York Yankees (3-0, 2nd in AL East) to T-Mobile Park to face the host Seattle Mariners (2-2, 4th in AL West). The Yankees have stormed out of the gate with a perfect start after sweeping their opening series, while Seattle has shown competitive play but sits .500 after four games. The Mariners host the three-game set, looking to slow down New York’s momentum in what figures to be a classic AL East vs. AL West pitching duel.

Recent Team Forms

Yankees (3-0): New York has looked dominant early, averaging solid run production while posting a strong team ERA and capitalizing on timely hitting. They enter this road series 3-0 straight up with offensive momentum and a deep (though injury-hit) lineup.

Mariners (2-2): Seattle has been competitive with flashes of strong pitching and power but has shown some inconsistency offensively. They’re 2-2 SU at home to begin the year and will rely on their ace to steady the ship in this series opener.

Probable Pitchers & Player Matchups

Yankees: LHP Ryan Weathers (0-0, making Yankees debut; career 4.94 ERA) vs. Mariners: RHP Luis Castillo (0-0, veteran ace with 3.55 career ERA)

Weathers, acquired in the offseason and making his club debut, brings a solid two-pitch mix (primarily fastball/changeup) with ground-ball tendencies but has shown command issues in past samples. He’ll face a Mariners lineup featuring Randy Arozarena (LF), Cole Bliss (2B), Dominic Canzone (RF), and speed/power threats like Julio Rodríguez and Cal Raleigh.

Castillo, Seattle’s longtime ace, relies on elite velocity, a devastating changeup, and slider to generate strikeouts and weak contact. He’ll square off against the Yankees’ star-studded core, including Aaron Judge (RF/DH), Juan Soto (LF), Giancarlo Stanton (DH/OF), and young contributors like Jasson Domínguez.

Key matchup edges: Castillo’s swing-and-miss arsenal and home dominance versus Weathers’ efficiency against Seattle’s patient, high-contact approach; Weathers’ ground-ball profile versus T-Mobile Park’s pitcher-friendly dimensions. Expect a low-scoring, high-strikeout affair.

Injury Report

Yankees

Anthony Volpe (SS): 10-Day IL (left shoulder surgery recovery) – out until early May.

Carlos Rodón (SP): 15-Day IL (left elbow surgery recovery) – out until late April/early May.

Gerrit Cole (SP): 15-Day IL (Tommy John surgery recovery) – out until mid-May.

Clarke Schmidt (SP): 60-Day IL (right elbow/internal brace surgery) – out until late May.
New York’s rotation and infield depth are significantly impacted early, forcing reliance on call-ups and bullpen games if needed.

Mariners

J.P. Crawford (SS): 10-Day IL (right shoulder soreness) – out until early April.

Miles Mastrobuoni (3B/INF): 10-Day IL (right calf strain) – out until early April.

Bryce Miller (SP): 15-Day IL (left oblique inflammation) – out until late April.

Carlos Vargas (RP): 15-Day IL (right lat strain) – out until early April.

Logan Evans (SP): 60-Day IL (arm) – long-term.
Seattle is thin in the infield and rotation but has promoted depth arms to cover short-term absences.

Series History

The Yankees have owned recent head-to-head play, going 5-1 against the Mariners in 2025 and holding a 13-6 edge over the last three seasons. All-time, the clubs remain competitive in interleague action, but New York has performed well on the road in these matchups. This marks the 2026 opener of the three-game series at T-Mobile Park.

Weather Updates

Game-time conditions at T-Mobile Park (retractable roof — status TBD but mild forecast favors open or partially open): ~49–50°F, mostly cloudy, light wind 4–7 mph (NNE), humidity ~54%, precipitation chance ~0–9% (no delays expected). Cool early-season evening weather with neutral park effects — no extreme wind or carry anticipated, favoring pitchers.

Game Odds

New York Yankees           – 115

Seattle Mariners              7.5

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 9:40 PM ET
Venue: Petco Park, San Diego, California
TV: FS1, Padres.TV, NBCS-BA | Radio: KNBR 680 / 1510 AM (SF), 97.3 The Fan / KWFN (SD)

Game Overview

This NL West divisional series opener features the visiting San Francisco Giants (0-3, 5th in NL West) looking to snap a three-game skid against the host San Diego Padres (1-2, 2nd in NL West). The Giants dropped their first three contests (including a tough series against the Tigers), while the Padres split early results and now host the first three games of the 2026 season series at Petco Park. Both clubs are still shaking off Opening Week rust in what figures to be a tightly contested rivalry matchup.

Recent Team Forms

Giants (0-3): San Francisco has struggled to generate consistent offense and has leaned heavily on the bullpen early, posting low run totals and a shaky 0-3 start both straight up and on the road.

Padres (1-2): San Diego has shown flashes of strong pitching and timely hitting in limited action, going 1-2 SU but remaining competitive at home and looking to build momentum in their first divisional series of the year.

Probable Pitchers & Player Matchups

Giants: RHP Landen Roupp (0-0, 7-7 with 3.80 ERA in 2025) vs. Padres: RHP Walker Buehler (0-0, 10-7 with 4.93 ERA in 2025)

Roupp, a young right-hander with solid command and a multi-pitch mix (fastball/slider/changeup), makes an early-season road start. He’ll face a Padres lineup featuring Fernando Tatis Jr. (RF), Manny Machado (3B), Jackson Merrill (CF/OF), Xander Bogaerts (SS/2B), and Luis Arraez (1B/INF) — a group that ranked 11th in wRC+ vs. righties last season and remains dangerous when healthy.

Buehler makes his highly anticipated Padres debut after a solid but injury-marred 2025. His fastball-curveball-slider arsenal and veteran experience will be tested by the Giants’ contact-oriented attack, including key contributors like Heliot Ramos (OF), Matt Chapman (3B/INF), and Jung Hoo Lee (OF).

Key matchup edges: Buehler’s big-stage pedigree and strikeout stuff versus Roupp’s efficiency against San Diego’s patient, power-heavy lineup; Roupp’s ground-ball tendencies versus Petco’s spacious outfield. Expect a low-scoring, pitcher-friendly game in the early-season conditions.

Injury Report

Giants

Hayden Birdsong (RHP): 60-Day IL (Grade 2 right forearm/UCL sprain — Tommy John surgery, out until 2027).

Sam Hentges (LHP): 15-Day IL (left shoulder/knee surgery).

Joel Peguero (RP): 15-Day IL (hamstring) — out until ~April 10.

Reiver Sanmartin (RP): 60-Day IL (strained right hip flexor).

Jason Foley (RP): 60-Day IL (right shoulder).

Randy Rodriguez (RP): 60-Day IL (right elbow).

Parks Harber (3B): OUT (expected return ~April 27).
San Francisco’s bullpen and rotation depth are significantly thinned, forcing heavy reliance on call-ups and high-leverage arms.

Padres

Joe Musgrove (RHP): 15-Day IL (elbow).

Yuki Matsui (LHP): 15-Day IL (left groin strain).

Griffin Canning (RHP): 15-Day IL (Achilles).

Matt Waldron (RHP): 15-Day IL (medical procedure/lower body).

Will Wagner (3B/INF): 10-Day IL (oblique).

Sung-Mun Song (INF): 10-Day IL (right oblique tightness).

Jason Adam (RP): 15-Day IL (quadricep).

Blake Hunt (C): Day-to-Day.
San Diego is thin in the rotation and bullpen but has promoted depth pieces to cover; no major changes expected for today’s active roster.

Series History

The Padres have dominated recent head-to-head play, going 10-3 against the Giants in 2025. All-time, the Giants hold a slight road edge (234-246), but San Diego has performed well at Petco in divisional matchups. This marks the 2026 opener of the three-game set, with the Padres hosting the first three contests.

Weather Updates

Game-time conditions at Petco Park: ~67–69°F, mostly cloudy to partly clear skies, light wind 6–8 mph, humidity ~82–84%, precipitation chance ~1–9% (no delays expected). Mild and comfortable early-season evening weather with neutral park effects — no extreme wind or carry issues anticipated.

Game Odds

San Francisco Giants      8.5

San Diego Padres             – 118

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 8:10 PM ET
Venue: Daikin Park, Houston, Texas
TV: NESN, Space City Home Network (SCHN) | Radio: WEEI 93.7 FM / WCCM 1490 AM (BOS), SportsTalk 790 (HOU)

Game Overview

This early-season interleague series opener features the visiting Boston Red Sox (1-2, 4th in AL East) traveling to face the host Houston Astros (2-2, 2nd/3rd in AL West) at Daikin Park. The Red Sox opened with a mixed 1-2 start, while Houston has shown early competitiveness in its first four games. The Astros host the three-game set, looking to leverage home-field advantage and bounce back from a subpar 2025 campaign.

Recent Team Forms

Red Sox (1-2): Boston has been competitive but inconsistent early, with solid offensive flashes tempered by starting pitching questions and bullpen usage. They enter this road series 1-2 straight up after a split in their opening games.

Astros (2-2): Houston has looked steady out of the gate with balanced contributions across the lineup and pitching staff. They’re 2-2 SU and will rely on home momentum to build on their early results.

Probable Pitchers & Player Matchups

Red Sox: LHP Ranger Suárez (0-0, 3.20 ERA in 2025) vs. Astros: RHP Lance McCullers Jr. (0-0, 6.51 ERA in 2025)

Suárez, the Red Sox’s big offseason acquisition from the Phillies, brings elite command, a fastball-changeup-cutter mix, and ground-ball tendencies after posting a 12-8 record and 3.20 ERA last season. He’ll face an Astros lineup featuring Jose Altuve (LF/2B), Yordan Alvarez (LF/DH), Alex Bregman (3B), and Christian Walker or similar depth pieces.

McCullers Jr., the veteran right-hander, relies on his signature curveball, fastball, and changeup to generate swings-and-misses but is coming off a tough 2025 (2-5, 6.51 ERA). He’ll square off against the Red Sox core, including Rafael Devers (3B), Jarren Duran (CF/OF), and emerging threats like Ceddanne Rafaela and Wilyer Abreu.

Key matchup edges: Suárez’s strike-throwing and weak-contact profile versus Houston’s patient, power-oriented approach; McCullers’ experience and curveball against Boston’s disciplined, lefty-heavy lineup. Daikin Park’s dimensions should play neutral-to-slightly hitter-friendly if the roof stays open.

Injury Report

Red Sox

Triston Casas (1B): 10-Day IL (left patellar tendon repair/knee) – out until early April at earliest.

Kutter Crawford (SP): 15-Day IL (right wrist subsheath tear/surgery) – out until late April/early May.

Patrick Sandoval (SP): 15-Day IL (left UCL repair/elbow) – out until early April.

Anthony Seigler (INF/C): 10-Day IL (left knee patellar tendinopathy).

Longer-term: Tanner Houck (SP, 60-Day IL – Tommy John) and Romy Gonzalez (1B/INF, 60-Day IL – shoulder).
Boston’s rotation and infield depth are tested early, forcing reliance on call-ups.

Astros

Josh Hader (RP): 15-Day IL (left biceps tendinitis) – out until late April/early May.

Zach Dezenzo (INF/OF): 10-Day IL (right elbow soreness).

Enyel De Los Santos (RP): 15-Day IL (right knee strain).

Additional: Hayden Wesneski (RP/SP, elbow), Ronel Blanco (SP, long-term Tommy John), and others on IL.
Houston is thin in the bullpen and has positional depth concerns but has managed early with promotions.

Series History

The clubs have been competitive in recent seasons, with Boston holding a 4-2 edge in 2025 head-to-head matchups. All-time, the Astros lead slightly in interleague play, but recent trends favor the visitor in low-scoring affairs at Daikin Park. This marks the 2026 opener of the three-game series.

Weather Updates

Game-time conditions at Daikin Park (retractable roof — status TBD but likely open or partially open given mild forecast): 77–78°F, partly cloudy skies, light winds ~5–10 mph, humidity ~60–70%, precipitation chance low (10%) with no delays expected. Mild and comfortable early-season weather—neutral park effects with minimal wind impact.

Game Odds

Boston Red Sox                 – 118

Houston Astros                 8.5

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 7:45 PM ET
Venue: Busch Stadium, St. Louis, Missouri
TV: SNY, Cardinals.TV | Radio: Audacy Mets Radio WHSQ 880AM / 92.3 HD2 (NYM), KMOX 1120 / 99.1 FM (STL)

Game Overview

This early-season interleague series opener sends the visiting New York Mets (2-1, 3rd in NL East) on the road to face the host St. Louis Cardinals (2-1, 2nd in NL Central) at Busch Stadium. The Mets opened with a strong 2-1 home series against the Pirates (including an 11-7 Opening Day win), while the Cardinals have shown early resilience in their first three contests. This marks the first 2026 meeting between the clubs, with St. Louis hosting the three-game set.

Recent Team Forms

Mets (2-1): New York posted an explosive 11-7 win on Opening Day and took a marathon extra-inning victory before dropping the series finale 4-3 in 10 innings. Offense has shown early pop (led by Juan Soto, Francisco Lindor, and Luis Robert Jr.), but the bullpen was taxed; they’re 2-1 straight up at home to start the year and now hit the road.

Cardinals (2-1): St. Louis has looked competitive early with solid run production and pitching depth in limited action. They’re 2-1 SU after a mixed opening stretch (including a high-scoring loss in the finale) and will lean on home-field momentum in this series opener.

Probable Pitchers & Player Matchups

Mets: RHP Clay Holmes (0-0, strong relief-to-starter transition profile) vs. Cardinals: RHP Kyle Leahy (0-0, ~4.00-ish early metrics)

Holmes, converted to a starting role with elite command and a sinker-slider-cutter arsenal, brings high-leverage experience but limited big-league starts. He’ll face a Cardinals lineup featuring Nolan Gorman (3B), Jordan Walker (RF), Pedro Pages (C), and young contributors like JJ Wetherholt (INF) and Masyn Winn (SS).

Leahy relies on a fastball-slider-changeup mix to induce weak contact and ground balls. He’ll square off against the Mets’ star-studded core, including Juan Soto (LF/DH), Francisco Lindor (SS), Luis Robert Jr. (CF), and emerging bats like Brett Baty and Carson Benge.

Key matchup edges: Holmes’ strike-throwing and swing-and-miss vs. St. Louis’ patient, power-oriented approach; Leahy’s contact management against New York’s disciplined, high-OBP lineup. Expect a competitive, potentially low-scoring game with Busch’s neutral-to-slightly pitcher-friendly dimensions in play.

Injury Report

Mets

A.J. Minter (RP): 15-Day IL (left lat surgery) – out until early May.

Dedniel Núñez (RP): 60-Day IL (elbow/Tommy John).

Tylor Megill (SP): 60-Day IL (elbow/Tommy John).

Justin Hagenman (SP): 60-Day IL (rib fracture).

Mike Tauchman (OF): OUT (left meniscus tear) – out until mid-May.
New York’s bullpen and rotation depth are tested early, relying on call-ups and high-leverage arms.

Cardinals

Hunter Dobbins (SP): 15-Day IL (knee) – out until early April.

Lars Nootbaar (LF): 60-Day IL (heels) – out until late May.

Additional depth arms noted on short-term IL. St. Louis is thin in the outfield and rotation but has promoted young talent to cover. No changes expected for today’s active roster.

Series History

The Mets hold a recent edge, winning 5-2 in the 2025 season series. All-time, the clubs have been competitive, but New York has performed well on the road in recent interleague play. This is the 2026 opener of the three-game set at Busch Stadium.

Weather Updates

Game-time conditions at Busch Stadium: ~81–84°F, mostly clear skies, wind 12–14 mph (south/southwest), humidity ~36–39%, precipitation chance ~1–10% (no delays expected). Unseasonably warm and ideal early-season baseball weather—comfortable temperatures with a light breeze that could play neutral-to-slightly hitter-friendly toward right/center but remains manageable.

Game Odds

New York Mets                 – 156

St. Louis Cardinals           8.5

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 7:40 PM ET
Venue: American Family Field, Milwaukee, Wisconsin
TV: Brewers.TV, Rays.TV | Radio: WTMJ 620 (MIL), WDAE 95.7 FM / WQBN 1300 AM (TB)

Game Overview

This interleague series opener pits the visiting Tampa Bay Rays (1-2, 4th in AL East) against the host Milwaukee Brewers (3-0, 1st in NL Central). The Rays split their season-opening series in St. Louis (winning the finale 11-7) but enter with offensive inconsistency and bullpen strain. The Brewers have dominated early, sweeping the White Sox with strong pitching and timely power. Milwaukee hosts the three-game set at American Family Field, where the retractable roof will likely be closed for comfortable early-season conditions.

Recent Team Forms

Rays (1-2): Tampa Bay showed late offensive life with an 11-7 win Sunday but dropped the first two games in extra innings and blowout fashion. Team ERA sits high (~6.84), and the bullpen has been overworked; they’re 1-2 on the road to start the year.

Brewers (3-0): Milwaukee has looked elite out of the gate, posting a sub-3.50 team ERA, .337 BA, and 29 runs scored. They’re 3-0 straight up and ATS with dominant home pitching and timely hitting.

Probable Pitchers & Player Matchups

Rays: RHP Nick Martinez (0-0, ~4.45 ERA career profile) vs. Brewers: LHP Kyle Harrison (0-0, ~4.04 ERA in limited 2025 action)

Martinez, in his Rays debut after a veteran campaign elsewhere, brings durability, a sinker-slider-changeup mix, and ground-ball tendencies but showed command issues in spring. He’ll face a Brewers lineup clicking early, led by Christian Yelich (LF, .600 AVG, 5 RBI, 1 HR), Jake Bauers, Brice Turang (2B), and power threats like William Contreras (C).

Harrison, the young lefty with strikeout upside and a fastball-changeup-curve arsenal, relies on command and inducing weak contact. He’ll square off against the Rays’ veteran core, including Yandy Díaz (1B, .563 AVG, 5 RBI, 4 hits Sunday), Jonathan Aranda (1B/INF), and speed/power from players like Jonny DeLuca.

Key matchup edges: Harrison’s lefty stuff vs. Tampa Bay’s patient, contact-heavy approach (especially Díaz); Martinez’s experience against Milwaukee’s aggressive, high-OBP lineup (.452). Expect a low-scoring, pitcher-friendly affair in the dome.

Injury Report

Rays

Taylor Walls (SS/INF): 10-Day IL (strained right oblique).

Gavin Lux (OF/INF): 10-Day IL (right shoulder impingement).

Edwin Uceta (RP): 15-Day IL (right shoulder impingement).

Manuel Rodríguez (RP): 60-Day IL (right elbow surgery – out for season).

Steven Wilson (RP): 60-Day IL (lumbar disc inflammation).

Ryan Pepiot (SP): 15-Day IL (right hip inflammation – out until ~April 6).

Jake Fraley (RF): Day-to-Day (undisclosed – scratched recently).
Tampa Bay’s infield, outfield depth, and bullpen are significantly thinned, forcing heavy reliance on call-ups.

Brewers

Andrew Vaughn (1B): 10-Day IL (hand).

Jackson Chourio (CF): 10-Day IL (hand – out until ~April 10).

Rob Zastryzny (RP): 15-Day IL (strained left shoulder).

Quinn Priester (SP): 15-Day IL (wrist).

Craig Yoho (RP): 15-Day IL (calf).

Eduardo Garcia (OF): Day-to-Day (undisclosed).
Milwaukee is missing key positional and bullpen depth but has covered well with strong early results and call-up flexibility. No changes expected for today’s active roster.

Series History

The Brewers hold a slight all-time edge at 13-12 (.520 winning percentage) across 25 meetings. Recent interleague play has been tightly contested (Brewers went 2-1 in 2024, 1-2 in 2025). This marks the 2026 opener of the three-game set, with Milwaukee hosting all three at American Family Field.

Weather Updates

Game-time conditions at American Family Field (retractable roof expected closed): 55–63°F (cooling into the low 50s by late evening), mostly cloudy, light winds ~10 mph, humidity ~70%, precipitation chance low (10–15%) with no delays expected. Dome closure eliminates any outdoor impact—neutral park factors with no wind or rain concerns.

Betting Trends

Early trends (small sample): Brewers are 3-0 SU/ATS with elite home pitching; Rays are 1-2 ATS as road underdogs. Totals have stayed under in Milwaukee’s wins. Home favorites off hot starts have performed well historically in interleague play.

Game Odds

Tampa Bay Rays                8

Milwaukee Brewers       – 163

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 7:40 PM ET
Venue: Wrigley Field, Chicago, Illinois
TV: MARQ Sports Network, FanDuel Sports Network West | Radio: 670 The Score (CHC), KLAA 830 AM (LAA)

Game Overview

This early-season interleague series opener brings the visiting Los Angeles Angels (2-2, 3rd in AL West) to Wrigley Field to face the host Chicago Cubs (1-2, 4th/5th in NL Central). The Angels have shown some offensive spark in their first four games, while the Cubs are still searching for consistency after a slow start. The Cubs host the three-game set, looking to leverage home-field advantage and Wrigley’s early-season quirks against an Angels club that’s split its road games so far.

Recent Team Forms

Angels (2-2): Los Angeles has been competitive, posting balanced scoring and solid bullpen work in limited action. They enter this road series 2-2 straight up with momentum from a recent split, though the starting rotation has been inconsistent.

Cubs (1-2): Chicago has struggled offensively early while showing flashes of strong pitching. They’re 1-2 SU at home to begin the year and will rely on timely hitting to bounce back in this series opener.

Probable Pitchers & Player Matchups

Angels: RHP Ryan Johnson (0-0, ~7.36 ERA in limited 2025 action) vs. Cubs: RHP Edward Cabrera (0-0, ~3.53 ERA career profile)

Johnson, a young right-hander with strikeout upside, relies on a fastball-slider-changeup mix but has shown command issues in small samples. He’ll face a Cubs lineup missing key pieces but still featuring Cody Bellinger (1B/OF), Ian Happ (LF), and emerging threats like Pete Crow-Armstrong (CF).

Cabrera brings elite velocity and swing-and-miss stuff with his fastball-slider-cutter arsenal. He’ll square off against the Angels’ veteran core, including Mike Trout (RF/DH), Alex Bregman (3B), and power bats like Taylor Ward and Logan O’Hoppe.

Key matchup edges: Cabrera’s strikeout ability versus Los Angeles’ patient, veteran approach; Johnson’s stuff against Chicago’s contact-oriented but currently depleted lineup. Expect a competitive game with potential for strikeouts and Wrigley wind playing a factor.

Injury Report

Angels

Robert Stephenson (RP): 60-Day IL (elbow) – out until at least late May.

Grayson Rodriguez (SP): 15-Day IL (shoulder inflammation) – out until ~April 6.

Vaughn Grissom (INF): 10-Day IL (left wrist sprain) – out until ~April 1–3.

Kirby Yates (RP): 15-Day IL (knee inflammation) – out until ~April 6.

Alek Manoah (SP): 15-Day IL (middle finger contusion) – out until ~April 6.

Anthony Rendon (3B): 60-Day IL (hip) – long-term absence.

Additional: Ben Joyce (RP) shoulder concerns noted earlier. Angels’ rotation and bullpen depth are tested early.

Cubs

Seiya Suzuki (RF/OF): 10-Day IL (right knee) – out until ~April 1–10.

Jordan Wicks (SP): 15-Day IL (elbow/forearm irritation) – out until ~April 15.

Porter Hodge (RP): 15-Day IL (elbow strain) – out until ~April 6.

Justin Steele (SP): 60-Day IL (elbow UCL revision) – out until late May.

Additional long-term: Shelby Miller (RP) and others on 60-Day IL. Cubs are thin in the outfield and rotation but have called up depth arms.

Series History

The Cubs hold the all-time edge 16-10 against the Angels. Recent interleague meetings have been competitive, but Chicago has performed well at home in these cross-league clashes. This marks the first 2026 series between the clubs, with the Cubs hosting all three games at Wrigley Field.

Weather Updates

Game-time conditions at Wrigley Field: 68–70°F (high near 70°, cooling into the mid-50s), partly cloudy skies, wind 15–16 mph southwest, humidity ~49–55%, precipitation chance low (10–20%) with no delays expected. Classic early-season Wrigley weather—mild temperatures with a breeze that could play slightly hitter-friendly toward the ivy but remains manageable.

Betting Trends

Early trends (small sample): Cubs are 1-2 SU but favored at home; Angels are 2-2 ATS as road underdogs. Totals have hovered around 9–10 in early Cubs contests. Home favorites in interleague openers have hit solidly historically.

Game Odds

Los Angeles Angels         10

Chicago Cubs                     – 194

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 7:15 PM ET
Venue: Truist Park, Atlanta, Georgia
TV: MLB.TV, NBCSCA (ATH), Bally Sports South / Bally Sports Southeast (ATL) | Radio: 650 KSTE / A’s Cast (OAK), 680 The Fan / 93.7 FM (ATL)

Game Overview

This interleague series opener features the visiting Athletics (0-3, 5th in AL West) looking to snap a winless start against the host Atlanta Braves (2-1, 4th in NL East). The A’s have dropped their first three games of the season, while Atlanta picked up a series win to open the year. The Braves host the three-game set at Truist Park, where they’ll look to capitalize on home-field advantage and early momentum.

Recent Team Forms

Athletics (0-3): Oakland has struggled offensively and with consistency early, posting low scoring output and facing bullpen strain. They’re 0-3 on the road to begin 2026 and enter this series still hunting their first victory.

Braves (2-1): Atlanta has shown solid early form with a series victory, displaying better run production and pitching depth in limited action. They’re 2-1 straight up and have looked competitive at home despite some roster challenges.

Probable Pitchers & Player Matchups

Athletics: LHP Jacob Lopez (0-0, strong strikeout profile ~10.9 K/9 in recent action) vs. Braves: RHP Bryce Elder (0-0, ~4.73 ERA career/home splits noted)

Lopez brings swing-and-miss stuff with a fastball-changeup-slider mix but can be prone to command issues. He’ll face a Braves lineup featuring Ronald Acuña Jr. (RF), Ozzie Albies (2B), and power threats like Matt Olson (1B) and emerging contributors such as Drake Baldwin (C).

Elder relies on a sinker-cutter-changeup arsenal to generate ground balls and weak contact. He’ll square off against the Athletics’ core, including Brent Rooker (DH/OF), Shea Langeliers (C), and hitters like Luis Urias or JJ Bleday looking to spark the offense.

Key matchup edges: Lopez’s strikeout upside versus Atlanta’s patient, power-oriented approach; Elder’s home-ground-ball tendencies against Oakland’s early-season contact struggles. Expect a competitive game with Truist Park’s dimensions playing neutral-to-slightly pitcher-friendly in mild conditions.

Injury Report

Athletics

Gunnar Hoglund (SP): 15-Day IL (knee) – out until at least early April.

Additional depth arms noted on short-term IL (one P expected out until ~April 10). Oakland’s rotation and bullpen depth are impacted early, relying on call-ups.

Braves

Spencer Strider (SP): 15-Day IL (left oblique strain) – out until ~April 6.

Sean Murphy (C): 10/60-Day IL (right hip labral tear) – out until at least May.

Ha-Seong Kim (SS): 10-Day IL (torn tendon in right finger).

Longer-term: Spencer Schwellenbach (SP, elbow), Hurston Waldrep (SP, elbow), Daysbel Hernández (RP, shoulder), Joe Jimenez (RP, knee), and others on IL.
Atlanta recently selected the contract of LHP Martin Perez and optioned Didier Fuentes to Triple-A to help cover rotation/bullpen depth. No changes expected for today’s active roster.

Series History

The Braves hold a strong historical edge: 15-5 in the last 20 meetings and 18-7 all-time against the Athletics franchise in select samples. Recent interleague play has favored Atlanta at home. This marks the 2026 opener of the three-game series.

Weather Updates

Game-time conditions at Truist Park: ~72°F, mostly clear/mild skies, light wind ~5–6 mph, humidity ~55%, precipitation chance ~6%. Excellent early-season baseball weather with no rain concerns—comfortable temperatures and minimal wind impact expected throughout the evening.

Betting Trends

Early trends (small sample): Braves are 2-1 SU with solid home trends; Athletics are 0-3 ATS as road underdogs. Totals have been manageable in Atlanta’s early games. Home favorites in interleague openers have performed well historically.

Game Odds

Athletics                              9

Atlanta Braves                  – 136

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026

First Pitch is scheduled for 7:07 PM ET
Venue: Rogers Centre, Toronto, Ontario
TV: Sportsnet (SNET), Rockies.TV, MLB.TV | Radio: Sportsnet 590 The Fan (TOR), KOA 850 AM / 94.1 FM (COL)

Game Overview

This interleague series opener highlights a tale of two very different early-season starts. The visiting Colorado Rockies (0-3, last in NL West) have been outscored and outplayed in their first three games, while the host Toronto Blue Jays (3-0, atop AL East) have looked sharp with strong pitching and timely offense. The Blue Jays are hosting the three-game set at Rogers Centre, looking to extend their perfect start against a Rockies club still searching for its first win of 2026.

Recent Team Forms

Rockies (0-3): Colorado has struggled across the board, posting a low batting average and allowing runs at a concerning clip early. Offense has been stagnant, and they enter this road series 0-3 straight up with no momentum.

Blue Jays (3-0): Toronto has been dominant out of the gate, boasting excellent team ERA, solid run production, and a perfect record both straight up and in early trends. They’re 3-0 at home and riding high after a strong opening stretch.

Probable Pitchers & Player Matchups

Rockies: RHP Tomoyuki Sugano (0-0, MLB debut) vs. Blue Jays: RHP Cody Ponce (0-0)

Sugano, the former KBO MVP making his highly anticipated Rockies (and MLB) debut, brings elite command, a deep pitch mix, and proven durability from overseas. He’ll face a Blue Jays lineup featuring George Springer (RF), Vladimir Guerrero Jr. (1B), and emerging threats like Bo Bichette and Daulton Varsho.

Ponce, returning to an MLB mound after time away, relies on his fastball-slider-cutter arsenal to generate weak contact and strikeouts. He’ll square off against the Rockies’ young core, including Ezequiel Tovar (SS), Hunter Goodman (C), and power bats looking to spark the offense.

Key matchup edges: Sugano’s international pedigree and strike-throwing versus Toronto’s patient, power-heavy lineup; Ponce’s experience against Colorado’s contact-oriented but currently slumping attack. Rogers Centre’s dimensions and early-season conditions should favor pitchers if both arms locate early.

Injury Report

Rockies

Zac Veen (OF): 10-Day IL (knee) – out until early April.

Mickey Moniak (RF): 10-Day IL (sprained right ring finger) – out until early April.

Tyler Freeman (OF/INF): 10-Day IL (lower back inflammation) – out until early April.

Blaine Crim (1B): 10-Day IL (oblique) – out until early April.

RJ Petit (RP): 60-Day IL (elbow).

Case Williams (SP): Day-to-day.
Colorado’s outfield and depth are thinned, forcing heavy reliance on call-ups and bullpen usage.

Blue Jays

Mason Fluharty (RP): Day-to-day (knee).

José Berríos (SP): 15-Day IL (elbow stress fracture) – out until late April.

Yimi García (RP): 15-Day IL (elbow).

Trey Yesavage (P): 15-Day IL (shoulder).

Bowden Francis (SP): 60-Day IL (elbow/UCL).

Shane Bieber (SP): 15-Day IL (elbow).

Anthony Santander (OF): 10-Day IL (shoulder).
Toronto is missing key rotation and bullpen arms but has managed depth well in the first three games. No major changes expected for today’s roster.

Series History

The Blue Jays have performed well in recent interleague matchups against the Rockies, including strong home results in prior seasons. This marks the 2026 opener of the three-game set, with Toronto hosting all three. Historical trends favor the home team in these cross-league early-season clashes.

Weather Updates

Game-time conditions at Rogers Centre (retractable roof — expected to be open or partially open): Mid-to-upper 40s°F (around 45–48°F at first pitch, cooling into the low 40s), mostly cloudy, wind 10–16 mph (west/southwest), humidity ~80–88%, precipitation chance ~10–15% (light showers possible but no delays expected). Cool early-season weather with a breeze that could slightly suppress fly balls; dome flexibility keeps conditions playable.

Betting Trends

Early trends (small sample): Blue Jays are 3-0 SU/ATS with dominant home pitching; Rockies are 0-3 ATS as road underdogs. Totals have stayed manageable in Toronto’s wins. Home favorites off strong starts have hit well historically.

Game Odds

Colorado Rockies             8.5

Toronto Blue Jays             – 293

Odds Courtesy of Sports Odds Direct as of Sunday, March 29, 2026