NBA Game Preview: Cleveland Cavaliers (37-23) vs. Detroit Pistons (43-14)

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Tipoff is scheduled for 7:00 PM ET
TV: ESPN (national), FanDuel Sports Network Detroit (FDSDET), FanDuel Sports Network Ohio (FDSOH)
Streaming: Fubo, NBA League Pass (blackout restrictions apply)

This is a marquee late-February matchup between two of the East’s top teams. The Pistons sit atop the Eastern Conference with the league’s best record, while the Cavaliers are fighting for homecourt advantage in the playoffs. Detroit is 22-7 at home this season and has won 8 of its last 10 games overall. Cleveland has also been hot (8-2 in its last 10) but enters severely shorthanded on the road (17-12 away record).

Injury Report
Cleveland Cavaliers – Heavily depleted

  • Out: Donovan Mitchell (right groin strain), Max Strus (left foot – Jones fracture surgery), Riley Minix (G League two-way)
  • Questionable: Keon Ellis (left index finger fracture), James Harden (right thumb fracture), Dennis Schroder (right ankle sprain), Dean Wade (right ankle sprain)

Detroit Pistons

  • Out: Bobi Klintman (G League assignment), Chaz Lanier (G League assignment), Wendell Moore Jr. (G League two-way), Isaiah Stewart (league suspension)
    No other major injuries; core rotation intact.

Recent Form
Pistons (43-14):
Red-hot at home. Most recent: W 124-116 vs. Oklahoma City (Feb 25) – Cade Cunningham 29 pts/13 ast, Jalen Duren 29 pts/15 reb. They are 5-2 ATS in their last 7 and have the East’s best net rating (+7.9). Defense ranks top-5 (109.5 PPG allowed).

Cavaliers (37-23): 4th in East. Most recent: L 116-118 @ Milwaukee (Feb 25), W 109-94 vs. New York (Feb 24). They average a scorching 119.5 PPG (3rd in NBA) but are vulnerable defensively (115.1 allowed, 15th). Road struggles are amplified without Mitchell.

Head-to-Head / Series History
2025-26 season (1-1):

  • Oct 27, 2025: CLE @ DET → Cavaliers 116-95
  • Jan 4, 2026: DET @ CLE → Pistons 114-110

Historically Pistons lead all-time 134-109, but Cleveland dominated recent seasons (won 12 straight from 2022-early 2025). Detroit has now won 2 of the last 3 meetings and covered the spread in both 2025-26 wins. The Under has hit in 8 of the past 10 head-to-head games.

Key Player Matchups

  • Cade Cunningham (DET, ~25.4 PPG, elite playmaking) vs. Cleveland backcourt (Darius Garland + Schroder/Harden if active): Cunningham has been unstoppable at home. Cleveland’s guard defense is stretched thin without Mitchell.
  • Jalen Duren (DET, dominant interior) vs. Evan Mobley / Jarrett Allen: Duren is averaging a double-double and feasts on second-chance points. Cleveland’s bigs are excellent but will be worked on the glass.
  • Tobias Harris / Ausar Thompson (DET wings) vs. James Harden (if plays) / Dean Wade or Keon Ellis: Detroit’s length and athleticism on the perimeter should bother a banged-up Cavs attack.
  • Bench edge: Pistons depth holds up better; Cleveland’s rotation is decimated if multiple questionables sit.

Betting Trends & Advanced Stats

  • Pistons are 19-9 ATS overall and 33-13 as moneyline favorites (22-2 when -249 or shorter).
  • Cleveland is 24-26 ATS and just 6-6 as underdogs.
  • Pistons average 117.4 PPG scored vs. Cleveland’s 115.1 allowed → Detroit projects ~118 points.
  • Cleveland averages 119.5 PPG but faces Detroit’s top-5 defense.
  • Over/Under trends favor the Under (hit in 4 of Pistons’ last 7 and 8 of last 10 H2H). Average combined total in recent meetings ~220-225.
  • Home favorite trends: Pistons cover ~65% at home vs. teams missing star players.

Game Odds

Cleveland Cavaliers        227.5

Detroit Pistons                 – 6.5

Odds Courtesy of Sports Odds Direct as of Thursday, February 26, 2026