NBA Game Preview: Boston Celtics (5-6) vs. Philadelphia Sixers (6-4)

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Venue & Game Information

Location: Xfinity Mobile Arena, Philadelphia, PA

Tip-off: 8:00 p.m. ET

Broadcast: NBC Sports Philadelphia / Peacock / NBA League Pass

Injury Report

Philadelphia 76ers:

OUT: Paul George (knee surgery recovery)

OUT: Dominick Barlow (elbow laceration)

OUT: Johni Broome (ankle sprain)

AVAILABLE: Jared McCain (brace/splint, cleared for limited minutes)

Boston Celtics:

OUT: Jayson Tatum (Achilles repair)

PROBABLE: Sam Hauser (wrist sprain)

Team Recent Form

Boston Celtics:

Won 111–107 vs. Orlando Magic on Nov. 9

Jaylen Brown scored 27 points; Anfernee Simons added 25

Averaging 112.5 points per game, allowing 114.8 points per game

Philadelphia 76ers:

Lost 111–108 vs. Detroit Pistons on Nov. 9

Tyrese Maxey scored 33 points, 7 assists; Andre Drummond posted 17 points, 12 rebounds

Averaging 118.2 points per game, allowing 113.1 points per game

Player Matchups

Celtics:

Jaylen Brown – 27 PPG over last two games, primary scorer with Tatum out

Derrick White – floor general, defensive anchor

Neemias Queta – rim protection, rebounding presence

76ers:

Tyrese Maxey – averaging 33.2 PPG this season, All-Star level play

Joel Embiid – dominant interior presence, matchup nightmare for Queta

VJ Edgecombe – rookie standout, consistent scoring support

Series History

All-time regular-season meetings: Boston leads 274–199

Last 10 matchups: Celtics lead 7–3

2025 season series: tied 1–1; last meeting Oct. 31, Celtics won 109–108

Betting Trends

Celtics: 2–3 in last 5 games; 3–6 ATS this season

Sixers: Lost 3 of last 4; 3–6 ATS overall

Over has hit in 5 of Sixers’ 10 games; Celtics trending Under in 3 of last 5

Predicted Score: Philadelphia 116 – Boston 108

Summary: This Eastern Conference clash pits a short-handed Celtics squad against a Sixers team leaning heavily on Tyrese Maxey’s scoring. With Jayson Tatum sidelined, Boston relies on Jaylen Brown and Simons, but Philadelphia’s combination of Embiid and Maxey plus home-court advantage makes them the safer bet. The suggested wagering model favors Sixers -2.5 and the Under.

Game Odds

Boston Celtics                   230.5

Philadelphia Sixers         – 1.5

Odds Courtesy of Sports Odds Direct as of Monday, November 10, 2025