NAIA-CFB Game Preview: Defiance (OH) Yellow Jackets (2-1) vs. Saint Francis (IN) Cougars  (2-1)

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Venue & Game Details

  • Kickoff Time: 1:00 PM ET
  • Venue: Bishop John M. D’Arcy Stadium, Fort Wayne, Indiana
  • Capacity: ~3,500
  • Event: USF Homecoming Game

Weather Forecast (Fort Wayne, IN)

  • Kickoff Temperature: ~22°C (72°F), cooling into the upper 60s by late afternoon
  • Conditions: Mostly sunny with scattered clouds
  • Wind: 10–14 km/h from the southwest
  • Precipitation:
  • Impact: Excellent football weather; minimal weather-related disruptions expected

Injury Report

  • Defiance Yellow Jackets:
    • QB group healthy; starter expected to play after steady early-season form.
    • RB rotation intact, no major reported injuries.
    • Secondary missing one rotational player (undisclosed).
  • Saint Francis Cougars:
  • QB group healthy; starter expected to play after narrow Week 1 loss to Campbellsville.
  • WR corps intact, including top target who has averaged over 80 yards per game.
  • Defensive line slightly banged up but starters expected to play.

(Note: NAIA programs release limited injury info; updates closer to kickoff may adjust this.)

Key Player Matchups

  • Defiance QB vs. USF Secondary
    • Defiance’s passing game has been efficient but turnover-prone.
    • USF’s secondary forced multiple turnovers in their opener vs. Campbellsville.
  • USF QB vs. Defiance Defensive Front
    • USF’s QB threw for 200+ yards and 2 TDs in Week 1.
    • Defiance’s front seven must generate pressure to disrupt his rhythm.
  • Special Teams Edge
  • Defiance’s kicker has been reliable from mid-range.
  • USF’s return game has consistently provided strong field position.

Recent Team Form

  • Defiance Yellow Jackets (1–0)
    • W 28–14 @ Judson (IL) (Sept 6)
    • Strengths: Balanced offense, opportunistic defense.
    • Weaknesses: Inexperienced depth, especially in secondary.
  • Saint Francis Cougars (0–1)
  • L 28–31 vs. #20 Campbellsville (KY) (Aug 30)
  • Strengths: Explosive passing game, home-field advantage.
  • Weaknesses: Defense allowed late-game scoring runs.

Conference vs. Conference

  • Defiance: Mid-South Conference (NAIA)
  • Saint Francis: Mid-States Football Association (NAIA)
  • This is a non-conference matchup, giving both programs a chance to test themselves outside league play.

Series History

  • All-time series: Saint Francis leads comfortably.
  • Last 5 meetings: USF has won all 5.
  • 2024 season: USF defeated Defiance 42–10 in Fort Wayne.
  • Trend: USF has consistently controlled the rivalry, especially at home.

Betting Trends

  • Defiance:
    • 1–0 ATS in 2025
    • 1–4 ATS in last 5 non-conference games
    • 3 of last 4 games have gone Under
  • Saint Francis:
  • 0–1 ATS in 2025
  • 4–1 ATS in last 5 vs. Defiance
  • 3 of last 4 games have gone Over

Historical Betting Results

  • 2024: USF -10.5 covered in a 42–10 win (Over cashed).
  • 2023: USF -7.5 covered in a 35–14 win (Under cashed).
  • 2022: USF -6.5 covered in a 31–17 win (Under cashed).

Game Odds

Defiance (OH) Yellow Jackets                      53

Saint Francis (IN) Cougars                            – 14

Odds Courtesy of Sports Odd Direct as of Friday, September 26, 2025