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MLB Game Preview: Toronto Blue Jays (12-11) vs. Houston Astros (11-11)

The Toronto Blue Jays (12-11) and Houston Astros (11-11) are set to face off in the second game of their three-game series on Tuesday, April 22, 2025, at Daikin Park in Houston. The Astros dominated the series opener with a 7-0 shutout victory, led by Hunter Brown’s stellar pitching performance.

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Game Details

  • Date: Tuesday, April 22, 2025
  • Time: 8:10 PM ET
  • Venue: Daikin Park, Houston, TX
  • TV Broadcast: Sportsnet, AT&T SportsNet Southwest
  • Series Status: Astros lead 1-0

Team Overview & Key Players

Houston Astros (11-11, 4th in AL West)

The Astros bounced back to .500 with their dominant win on Monday, shutting out the Blue Jays behind Hunter Brown’s seven-inning gem. Houston’s offense came alive in the fifth inning, scoring four runs, followed by three more in the seventh and eighth innings.

Key Players

  • José Altuve (2B) – Went 1-for-3 with two RBIs in Game 1.
  • Yordan Álvarez (OF) – Added an RBI, continuing his strong offensive presence.
  • Ronel Blanco (SP) – Set to start; holds a 1-2 record with a 6.48 ERA, looking to rebound after a rough start against St. Louis.

Toronto Blue Jays (12-11, 3rd in AL East)

The Blue Jays have lost three straight games, struggling offensively in their series opener, managing just two hits against Houston’s pitching staff. They’ll look to bounce back with Chris Bassitt on the mound, who has been dominant this season.

Key Players

  • Vladimir Guerrero Jr. (1B) – Needs to spark the offense after going hitless in Game 1.
  • Bo Bichette (SS) – Also struggled, grounding out in his final at-bat.
  • Chris Bassitt (SP) – Set to start; holds a 2-0 record with a stellar 0.77 ERA, looking to continue his dominance.

Game 2 Pitching Matchup

PitcherTeamRecordERALast Start
Ronel BlancoAstros1-26.485.0 IP, 3 ER vs. Cardinals
Chris BassittBlue Jays2-00.776.0 IP, 1 ER vs. Yankees

Blanco has struggled, allowing three earned runs in his last start, while Bassitt has been dominant, allowing just one earned run in his last outing.

Game Outlook & Predictions

  • Astros’ Strategy: Expect Houston to rely on early offense, using Altuve and Álvarez to set the tone.
  • Blue Jays’ Adjustments: Toronto must capitalize on scoring opportunities and limit strikeouts against Blanco.
  • X-Factor: Chris Bassitt’s ability to control Houston’s lineup could be the difference-maker.

Game Odds

Toronto Blue Jays                             8

Houston Astros                                 – 112

Odds Courtesy of Sports Odds Direct as of Monday, April 21, 2025

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